Poster Keyword Tables

Abstract #	Authors	Affiliation	Title / Session	Products
50	Emmanuel S. Spanos, Meng Wang, Amin Sabet, Esther Redin, Charles M. Rudin, Joseph Chan	Physiology, Biophysics, and Systems Biology, Weill Cornell Grad. School of Medical Sci., New York, NY | Memorial Sloan Kettering Cancer Center, New York, NY	Spatial transcriptomics uncovers patterns of transcriptional reprogramming and immune evasion in small cell lung cancer 4/19/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 1 Open abstract	Xenium
667	Maxim Norkin, Jonathan Bac, Louis McConnel, Sylvie Andre, Marina Alexandra Gaveta, Joerg Huelsken, Marianna Rapsomaniki, Raphael Gottardo, Krisztian Homicsko	Oncology, CHUV, Centre hospitalier universitaire vaudois, Lausanne, Switzerland | EPFL, Lausanne, Switzerland	Mapping and targeting spatial heterogeneity in CRC through patient-derived organoids 4/19/2026 2:00:00 PM | Ex Vivo Systems: Patient-Derived, Patient-Specific Tumor Cultures Open abstract	Xenium
795	Atefeh Khakpoor, Qanber Raza, Merrin Mary Eapen, Dina Kazemi, Erin Coll, Liang Lim, Christina Loh, Nick Zabinyakov, Ling Qiao, Anna Di Bartolomeo, Helen McGuire, Jacob George, Ankur Sharma	Garvan Institute, Sydney, Australia | Standard BioTools, Markham, ON, Canada | University of Sydney, Sydney, Australia | Storr Liver Centre, Sydney, Australia | The University of Sydney, Sydney, Australia	Integrating spatial transcriptomics and Imaging Mass Cytometry™ for multi-omic mapping of hepatocellular carcinoma 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	Xenium
802	Thao Tran, Máikel L. Colli, Nathan H. Patterson, Qanber Raza, Liang Lim, Lauren Tracey, Alice Ly, Sanja Bajovic, James Mansfield, Christina Loh, Marc Claesen	Aspect Analytics NV, Genk, Belgium | Standard BioTools, Markham, ON, Canada	Multi-omic profiling maps the immune multicellular environment of renal cell carcinoma 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	Xenium
898	Nicole Mavingire, Abdulrahman M. Dwead, Joy Solomon, Janelle Moore, Moyinoluwa Adeniyi, Odunayo Oluokun, Jabril R. Johnson, Estefania Labanca, Peter Shepherd, Mya Walker, Isaiah Sailors, Serene Dowiri, Greisha L. Ortiz Hernandez, Jillian C. McDonough, Diana LeVasseur, Jazlyn Farlough, Justin Tran, Frank Myers, Fornati Bedell, Zhirong Yin, Rachel Martini, Melissa B. Davis, Clayton C. Yates, K. Sean Kimbro, Rick A. Kittles, Tanya Dorff, Cristina Magi-Galluzzi, Soroush Rais-Bahrami, Firas Kobeissy, Yehia Mechref, Leanne Woods-Burnham	Morehouse School of Medicine, Atlanta, GA | Texas Tech University, Lubbock, TX | UT MD Anderson Cancer Center, Houston, TX | City of Hope National Medical Center, Duarte, CA | Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD | The University of Alabama at Birmingham, Birmingham, AL | Wake Forest University School of Medicine, Winston-Salem, NC	HER2 as a therapeutic target in prostate cancer: Multi-omic and spatial insights across genetic ancestries 4/19/2026 2:00:00 PM | Survivorship Research Addressing Cancer Disparities Open abstract	Xenium
1028	Michael Wegert-Verhoeven, Mathea Fransisca, Sylvia Martin, Attila Jady, Daniela Richter, Malgorzata Oles, Timon A. Blindauer, Jan-Philipp Mallm, Jasmina Paluncic, Claudia Dagostino, Olga Ermakova, Annika Schneider, Matthew The, Annika Baude-Müller, Katja Beck, Maximilian Bullemer, Victor Didier Perez Meza, Vivek Venkataramani, Ralf C. Bargou, Heiko Becker, Melanie Boerries, Armin Tuchscherer, DKFZ/NCT/DKTK MASTER consortium, Martin Wermke, Andreas Brunschweiger, Mohammed Al-Saeedi, Dirk Jäger, Olaf Witt, Denis Schapiro, Bernhard Küster, Andreas Hartig, Michael Allgaeuer, Alexander Brobeil, Christoph E. Heilig, Maria Veronica Teleanu, Simon Kreutzfeldt, Peter Horak, Daniel Hübschmann, Wolfgang Hartmann, Marcel Trautmann, Ina Oehme, Claudia R. Ball, Stefan Fröhling, Stefan M. Pfister, Hanno Glimm, Sebastian M. Dieter	Section Translational Precision Oncology, Division of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), Translational Functional Cancer Genomics, NCT Heidelberg and DKFZ, Heidelberg, Germany | Department for Translational Medical Oncology, NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany | Department for Translational Medical Oncology, NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden and Helmholtz-Zentrum Dresden-Rossendorf (HZDR); German Cancer Consortium (DKTK), Partner Site Dresden, Dresden, Germany | Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), NCT Heidelberg and DKFZ, Heidelberg Germany, Heidelberg, Germany | Institute for Computational Biomedicine, Faculty of Medicine, University Hospital Heidelberg, Heidelberg University; Translational Spatial Profiling Center (TSPC), Heidelberg; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany | Single-cell Open Lab, DKFZ, Heidelberg, Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), Heidelberg University, Heidelberg, Germany | Division of Pediatric Neurooncology, DKFZ, Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany | School of Life Sciences, Technical University of Munich, Freising, Germany | Division of Translational Medical Oncology, DKFZ, Heidelberg, National Center for Tumor Diseases (NCT), NCT Heidelberg, A Partnership Between DKFZ, The University Hospital Heidelberg (UKHD), The Heidelberg Medical Faculty of the Heidelberg University, and The Thorax Clinic Heidelberg, Heidelberg, Germany | Division of Translational Medical Oncology, DKFZ, Heidelberg, National Center for Tumor Diseases (NCT), NCT Heidelberg, A Partnership Between DKFZ, The University Hospital Heidelberg (UKHD), The Heidelberg Medical Faculty of the Heidelberg University, and The Thorax Clinic Heidelberg; DKTK, Core Center Heidelberg,, Heidelberg, Germany | Institute for Computational Biomedicine, Faculty of Medicine, University Hospital Heidelberg, Heidelberg University, Heidelberg, Germany | Comprehensive Cancer Center Mainfranken, NCT WERA, University Hospital Würzburg, Würzburg, Germany | Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany | Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg; DKTK, Partner site Freiburg, a partnership between DKFZ and Medical Center - University of Freiburg, Freiburg, Germany | Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Faculty of Medicine and University Hospital, Cologne, Heidelberg, Germany | Molecularly Aided Stratification for Tumor Eradication Research Program, NCT Berlin, NCT Dresden, NCT Heidelberg, NCT SüdWest, NCT WERA, NCT West, DKFZ; DKTK sites: Berlin, Dresden, Essen/Düsseldorf, Frankfurt/Mainz, Freiburg, Heidelberg, München, Tübingen, One NCT, Germany | TU Dresden, NCT/UCC Early Clinical Trial Unit and Medical Clinic and Poliklinik I, University of Technology Dresden (TUD), Dresden, Germany | Institute of Pharmacy and Food Chemistry, Julius-Maximilians-Universität Würzburg, Am Hubland, Würzburg, Germany | Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany | Department of Medical Oncology, NCT Heidelberg and Heidelberg University Hospital, Heidelberg, Germany | Clinical Cooperation Unit Pediatric Oncology, DKFZ and DKTK, Hopp Children's Cancer Center Heidelberg (KiTZ); Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany | School of Life Sciences, Technical University of Munich, German Cancer Consortium (DKTK), partner site Munich a partnership between DKFZ and Technical University of Munich (TUM), Munich, Germany | Institute of Pathology, Carl Gustav Carus University Hospital, Dresden, Germany | Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany | Institute of Pathology, University Hospital Heidelberg, Tissue Bank of the NCT, Heidelberg, Heidelberg, Germany | Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), NCT Heidelberg and DKFZ; DKTK, Core Center Heidelberg, Heidelberg, Germany | West German Cancer Center, University Hospital Münster, Münster, Germany | Clinical Cooperation Unit Pediatric Oncology, NCT and DKFZ Heidelberg and DKTK Heidelberg, Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany | Department for Translational Medical Oncology, NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden and Helmholtz-Zentrum Dresden-Rossendorf (HZDR); TUD Dresden University of Technology, Faculty of Biology, Dresden, Germany | Division of Translational Medical Oncology, DKFZ, Heidelberg, National Center for Tumor Diseases (NCT), NCT Heidelberg, A Partnership Between DKFZ, The University Hospital Heidelberg (UKHD), The Heidelberg Medical Faculty of the Heidelberg University, and The Thorax Clinic Heidelberg; DKTK, Core Center Heidelberg, Heidelberg, Germany | Division of Pediatric Neurooncology, DKFZ, Heidelberg, Hopp Children's Cancer Center Heidelberg (KiTZ); Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany | Department for Translational Medical Oncology, NCT/UCC Dresden, Translational Functional Cancer Genomics, NCT Heidelberg and DKFZ; German Cancer Consortium (DKTK), Partner Site Dresden, Dresden, Germany | Section Translational Precision Oncology, Division of Translational Medical Oncology, NCT and DKFZ Heidelberg; Department of Medical Oncology, NCT Heidelberg and Heidelberg University Hospital, Heidelberg, Germany	A tumor-agnostic YAP/TAZ score predicts TEAD inhibitor sensitivity independent of Hippo alterations 4/19/2026 2:00:00 PM | Biomarkers Predictive of Therapeutic Benefit 1 Open abstract	Xenium
1098	Jeremy L. Davis, Amber Famiglietti, Yunhe Liu, Rachael Belcher, Sun A Kim, Baktiar O. Karim, Donna Butcher, Linghua Wang	University of Maryland School of Medicine, Baltimore, MD | Department of Surgery, Georgetown University, Washington, DC | UT MD Anderson Cancer Center, Houston, TX | Laboratory of Pathology, National Cancer Institute, Baltimore, MD | Frederick National Laboratory for Cancer Research, Frederick, MD	Discrete precancer subtypes and biomarkers of cancer progression identified with spatiotemporal analysis of CDH1-driven diffuse gastric cancer 4/19/2026 2:00:00 PM | Early Detection Biomarkers 1 Open abstract	Xenium
1154	Eun Seop Seo, JI WON LEE, In Woo Hwang, Woong-Yang Park, Jun Sun Kim, Ki Woong Sung	Samsung Medical Center, Seoul, Korea, Republic of | Geninus, Seoul, Korea, Republic of	Multi-omic profiling of cellular heterogeneity and microenvironmental remodeling underlying treatment resistance in neuroblastoma 4/19/2026 2:00:00 PM | Mechanistic Insights for Targeted Therapies in Pediatric Cancer Open abstract	Xenium
1201	Yunhe Liu, Idania Carolina Lubo Julio, Wei Lu, Alejandra G. Serrano, Jean R. Clemenceau, Amber Famiglietti, Karen Colbert, Yibo Dai, Yang Liu, Jun Wang, Jeremy L. Davis, Mingyao Li, Paul F. Mansfield, Tae Hyun Hwang, Luisa M. Solis-Soto, Linghua Wang	Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Surgery, Vanderbilt University Medical Center, Nashville, TN | National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD | Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX | BioChemistry&Molecular Biology, University of Maryland School of Medicine, Baltimore, MD | University of Pennsylvania, Philadelphia, PA | Vice President, Acute Care Services, UT MD Anderson Cancer Ctr., Houston, TX | Department of Translational Molecular Pathology, the university of MD Anderson cancer center, Houston, TX	Spatial 3D and multi-omics mapping of diffuse gastric cancer evolution from preinvasive to invasive lesions in CDH1 mutation carriers 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium; CosMx; GeoMx; G4X
1203	Tian Chu, Jimin Min, Yunhe Liu, Yang Liu, Yibo Dai, Kyung Serk Cho, Xueshuai Han, Kai Yu, Fuduan Peng, Anirban Maitra, Humam Kadara, Linghua Wang	Genomic Medicine, UT MD Anderson Cancer Center, Houston, TX | Medicine, New York University Grossman School of Medicine, New York, NY | UT MD Anderson Cancer Center, Houston, TX | Department of Pathology, New York University Grossman School of Medicine, New York, NY	Spatial archetypes of conserved and cancer-specific immune-stromal niches 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium
1204	Adam Thiesen, Sema Akkurt, Javad Noorbakhsh, Te-Chia Wu, Andrew Salner, Peter Yu, Susan Airhart, Olga Anczukow, Ron Korstanje, Karolina Palucka, Jeffrey H. Chuang	The Jackson Laboratory for Genomic Medicine, Farmington, CT | Jackson Laboratory, Farmington, CT | | The Jackson Laboratory, Bar Harbor, ME | The Jackson Laboratory, Farmington, CT	Spatial multiomic characterization of spontaneous lung tumors in aged mice 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium
1205	Junyan Liu, Md Tauhidul Islam, Lei Xing	Stanford University, Palo Alto, CA	Trajectory-aware spatial transcriptomics deconvolution via image representation of RNA-seq data 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium
1206	Domenico Calafato, Yiheng Tang, Gleb Rukhovich, Elyas Heidari, Leonille Schweizer, Michael Weller, Christine Haberler, Till Acker, Bhuvic Patel, Abigail Suwala, Felix Sahm, Felix Hartmann, Moritz Gerstung	Division of Artificial Intelligence in Oncology, DKFZ German Cancer Research Center, Heidelberg, Germany | Institute of Neurology (Edinger Institute), University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany | Department of Neurology, Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland | Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria | Institute of Neuropathology, University hospital Giessen, Giessen, Germany | Department of Neurosurgery, Washington University School of Medicine, St. Louis, MO | Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany | Division of Systems Immunology and Single cell Biology, DKFZ German Cancer Research Center, Heidelberg, Germany	Large-scale spatial molecular profiling uncovers distinct macrophage activation states across meningioma methylation classes 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium
1208	Mitsuho Imai, Eun Seop Seo, Jiyeon Hyeon, Shingo Sakashita, Yuka Nakamura, Tadayoshi Hashimoto, Shin Kobayashi, Jun Yuda, Riu Yamashita, Taro Shibuki, Takao Fujisawa, Masataka Amisaki, Kensuke Matsuda, Shun-ichiro Kageyama, Michiko Nagamine, Takeshi Kuwata, Hideaki Bando, Woong-Yang Park, Takayuki Yoshino	National Cancer Center Hospital East, Kahsiwashi, Japan | GxD Inc, Seoul, Korea, Republic of | GxD Inc, Kashiwashi, Japan | National Cancer Center Hospital East, Kashiwashi, Japan | National Cancer Center Hospital East, Kashiwanoha, Japan | Pathology, NCCHE, Kashiwa, Japan | National Cancer Center Hospital East, Kashiwa, Japan	The MONSTAR-SCREEN-3 Spatial Atlas: Pan-cancer TME archetypes and clinically relevant tumor-immune ecosystems 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium
1210	Kazutaka Otsuji, Tomo Osako, Yoko Takahashi, Chikako Shibata, Sumito Saeki, Asumi Iesato, Tetsuo Noda, Kengo Takeuchi, Takayuki Ueno, Reo Maruyama	NEXT-Ganken Program, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Division of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Breast Oncology Center, Cancer Institute Hospital of JFCR, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Division of Cancer Epigenomics, Cancer Institute, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Director's room, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan	Integrated spatial and single-cell profiling uncovers a pre-existing, treatment-resistant subclone that drives early local relapse in luminal breast cancer 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium
1223	Nicholas E. Bingham, Julie R. Boiko, Daniel C. Jones, Daniel Wong, Tiffany Khong, Sridurga Mithraprabhu, Kathleen S. Ensbey, Anna E. Elz, Evan W. Newell, Andrew Spencer, Geoffrey R. Hill	Australian Centre for Blood Diseases, Alfred Health - Monash University, Melbourne, Australia | Translational Science and Therapeutics Division, Fred Hutchison Cancer Centre, Seattle, WA | Vaccine and Infectious Diseases Division, Fred Hutchison Cancer Centre, Seattle, WA | Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Centre, Seattle, WA	Spatial transcriptomics identifies a suppressive T-cell excluded tumour microenvironment in extramedullary multiple myeloma 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium
1293	J. Louw, T. N. Nandi, E. Calabrese, R. E. Mclendon, Y. Sun, J. Hickey, J. Jepson, A. Corcoran, K. Zhang, R. K. Madduri, M. Khasraw; Duke University, Durham, NC, US Department of Energy, Chicago, IL, Duke University Medical Center, Durham, NC, Duke Cancer Institute, Durham, NC		A multimodal AI framework integrating spatial omics and radiomics for recurrence prediction in glioblastoma 4/19/2026 3:20:00 PM | Integrative Computational Approaches Open abstract	Xenium
1419	Bohyeon Yu, Emanuele Filiberto Rosatti, Jangham Jung, Abhinav Jain, Joanna Phillips, Aaron Antonio Diaz	Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA | Department of Cellular, Computational and Integrative Biology, University of Trento, Trentino, Italy	Integrated spatial and genetic lineage tracing uncovers cell state plasticity underlying recurrence in group3 and group4 medulloblastoma 4/20/2026 9:00:00 AM | Application of Bioinformatics to Cancer Biology 2 Open abstract	Xenium; Visium
1476	Steven Yan, Limin Jiang, Yan Guo	University of Miami Miller School of Medicine, Miami, FL | University of Miami, Miami, FL	Improve spatial transcriptomic data with integrated hybrid transformer and graph convolutional networks 4/20/2026 9:00:00 AM | Integrative Computational Approaches 1 Open abstract	Xenium; Visium; CosMx
1484	Yongjoon Jin, Jeong-Yeon Ji, Hyojung Lee, Na-yeon Kim, Eun-Jae Chung, Jong-Il Kim	Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Korea, Republic of | Department of Otorhinolaryngology-Head and Neck Surgerys, Seoul National University Bundang Hospital, Gyeonggi-do, Korea, Republic of | Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Korea, Republic of | SNU Medicine, Seoul, Korea, Republic of	p-EMT transitional hub and its DC2-macrophage niche define recurrence in oral squamous cell carcinoma 4/20/2026 9:00:00 AM | Integrative Computational Approaches 1 Open abstract	Xenium
1487	Raymond Yan, Brian Falkenstein, A. Burak Tosun, Filippo Pullara, S. Chakra Chennubhotla	PredxBio, Inc., Pittsburgh, PA | PredxBio, Inc. / University of Pittsburgh, Pittsburgh, PA	Spatial microdomains from histology reveal multi-omic biomarkers for enhanced idiopathic pulmonary fibrosis diagnosis 4/20/2026 9:00:00 AM | Integrative Computational Approaches 1 Open abstract	Xenium; Visium
2218	Zizhou Wang, Hiroaki Kasashima, Yukina Kusunoki, Yasuhiro Fukui, Iguru Omori, Nobuhiro Naito, Hideki Tanda, Yuki Seki, Kenji Kuroda, Yuichiro Miki, Mami Yoshii, Tatsuro Tamura, Masatsune Shibutani, Takahiro Toyokawa, Yu Muta, Yuki Nakanishi, Masakazu Yashiro, Kiyoshi Maeda	Department of Gastroenterological Surgery, Osaka Metropolitan University, Osaka, Japan | Department of Pathophysiology, Osaka Metropolitan University, Osaka, Japan | Department of Gastroenterology and Hepatology, Kyoto University, Japan, Kyoto, Japan | Department of Molecular Oncology and Therapeutics, Osaka Metropolitan University, Osaka, Japan	Tertiary lymphoid structures in colorectal cancer: Clinical significance and their interaction with CAFs and the immune microenvironment 4/20/2026 9:00:00 AM | Tertiary Lymphoid Structures in Cancer Open abstract	Xenium
2253	Fushun Chen, Lorena Isabel Gomez, Tieling Zhou, Yuejiang Liu, Inti C. Tarifa Reischle, Sujuan Yang, Manvi Sharma, ,Jiping Feng, Jaafar Hadi, Fuduan Peng, Yibo Dai, Mhenaz Hossain, Ratna Veeramachaneni, Ansam Sinjab, Sean Anderson, Dhrishit Mangrolia, Deborah Rodriguez, Nadim Ajami, Jennifer Wargo, Adel El-Naggar, Roberto Rangel, Nadarajah Vigneswaran, Linghua Wang, Jeffrey N. Myers, Humam Kadara	UT MD Anderson Cancer Center, Houston, TX | UT Health School of Dentistry, Houston, TX	Multimodal and multikingdom spatial transcriptomics identify bacterial niches implicated in oral cancer development 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2255	Yibo Dai, Fuduan Peng, Ansam Sinjab, Yunhe Liu, Sujuan Yang, Lorena I Gomez Bolanos, Tieling Zhou, Minyue Chen, Alejandra G Serrano, Jianlong Liao, Guangsheng Pei, Yang Liu, Jiahui Jiang, Kyung Serk Cho, Kai Yu, Jiping Feng, Zahraa Rahal, Naoe Jimbo, Takuo Hayashi, Satsuki Kishikawa, Kazuya Takamochi, Avrum Spira, Steven M. Dubinett, Tomoo Itoh, Takashi Yao, Kenji Suzuki, Stephen G. Swisher, Mingyao Li, Junya Fujimoto, Ignacio Wistuba, Jared K. Burks, Kadir Caner Akdemir, Hind Rafei, Katayoun Rezvani, Jeffrey N. Myers, Humam Kadara, Linghua Wang	UT MD Anderson Cancer Center, Houston, TX | Kobe University Hospital, Kobe, Japan | Juntendo University Graduate School of Medicine, Tokyo, Japan | Lung Cancer Initiative at Johnson and Johnson, Boston, MA | UCLA David Geffen School of Medicine, Los Angeles, CA | University of Pennsylvania, Philadelphia, PA | Hiroshima University Hospital, Hiroshima, Japan | Moffitt Cancer Center & Research Institute, Tampa, FL	Spatial transcriptomics reveals evolving tumor microenvironmental archetype along the lung premalignancy-adenocarcinoma continuum 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2259	Siyuan He, Aatish Thennavan, Runmin Wei, Shanshan Bai, Jianzhuo Li, Chante Bethell, Emi Sei, Mitchell Rao, Tapsi Kumar, Chenling Tang, Ivan Marin, Jessica Montalvan, Chandandeep Nagi, Bora Lim, Savitri Krishnamurthy, Alastair Thompson, Nicholas E. Navin	UT MD Anderson Cancer Center, Houston, TX | Baylor College of Medicine, Houston, TX | Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, TX	Reprogramming of the stromal and immune microenvironment in preinvasive breast cancer 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2272	Akifumi Mochizuki, Ayako Suzuki, Kouya Shiraishi, Masahiro Torasawa, Takayuki Honda, Susumu Kirimura, Yasunari Miyazaki, Kenichi Okubo, Syuzo Kaneko, Yukihiro Yoshida, Shun-ichi Watanabe, Masahiro Tsuboi, Genichiro Ishii, Issei Imoto, Ryuji Hamamoto, Yasushi Yatabe, Yutaka Suzuki, Takashi Kohno	Department of Respiratory Medicine, Institute of Science Tokyo, Tokyo, Japan | Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan | National Cancer Center Research Institute, Tokyo, Japan | Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan | Division of Pathology, Institute of Science Tokyo, Tokyo, Japan | Department of Thoracic Surgery, Institute of Science Tokyo, Tokyo, Japan | Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan | Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan | Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan | Department of Pathology and Clinical laboratories, National Cancer Center Hospital East, Kashiwa, Japan | Dept. of Human Genetics, Inst. of Health Biosciences, Aichi Cancer Center Research Institute, Nagoya, Japan | Associate Professor, National Cancer Center Japan, Tokyo, Japan | Chief, Dept. of Pathology & Molec. Diagnostics, National Cancer Center, Nagoya, Japan	Dichotomous immunogenetic landscape of lung adenocarcinoma associated with usual interstitial pneumonia 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2708	Robert F. Gruener, Weijie Zhang, Lilin Wang, Adam M. Lee, R. Stephanie Huang	University of Minnesota, College of Pharmacy, Minneapolis, MN | University of Minnesota, Minneapolis, MN | Asst. Professor, Dept. of Medicine, University of Minnesota, Minneapolis, MN	Revealing fibroblast-mediated impacts to therapy response through spatially resolved drug response prediction in lung cancer 4/20/2026 2:00:00 PM | Integration of Clinical and Research Data Open abstract	Xenium; CosMx
2711	Daria Buszta, Jonathan Bac, Maxim Norkin, Arsh Shaikh, Bernd Illing, Adriano Martinelli, Isinsu Katircioglu, Melissa Ensmenger, Sylvie Andre, Marina Alexandre-Gaveta, Sanjay Popat, Anthony Pope, Riyaz Shah, Toby Talbot, Julia Giner, Janthur Wold-Dieter, Ernst Nadal, Annamaria Catino, David Gilligan, Amy Roy, Georgia Dimopoulou, Rosita Kammler, Stephen P. Finn, Zoi Tsourti, Enriqueta Felip, Patrick Vagenknecht, Solange Peters, Rolf A. Stahel, Marianna Rapsomaniki, Raphael Gottardo, Krisztian Homicsko	Biomedical Data Science Center, Lausanne University Hospital; University of Lausanne, Lausanne, Switzerland | Department of Oncology, Lausanne University Hospital; Swiss Cancer Center Leman, Lausanne, Switzerland | Department of Medicine, The Royal Marsden Hospital - NHS Foundation Trust, London, United Kingdom | Department of Oncology, Clatterbridge Cancer Centre NHS, Liverpool, United Kingdom | Department of Medical Oncology, Kent Oncology Centre Maidstone, Kent, United Kingdom | Department of Medical Oncology, Royal Cornwall Hospital, Turuto, United Kingdom | Department of Medical Oncology, Parc Tauli Hospital Sabadell, Sabadell, Spain | Department of Medical Oncology, Kantonsspital Aarau, Aarau, Switzerland | Department of Medical Oncology, ICO Hospitalet (Bellvitge), Barcelona, Spain | Department of Medical Oncology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy | Department of Medical Oncology, Addenbrooke’s Hospital, Cambridge, United Kingdom | Department of Medical Oncology, University Hospital Plymouth, Plymouth, United Kingdom | ETOP Statistical Center, Frontier Science Foundation – Hellas, Athens, Greece | Translational Research Coordination, ETOP IBCSG Partners Foundation, Bern, Switzerland | Pathologist, University of Dublin and St. James's Hospital, Dublin 8, Ireland | VHIO Vall D'Hebron Institute of Oncology, Barcelona, Spain | CHUV Lausanne University Hospital, Lausanne, Switzerland | University Hospital Zürich, Zürich, Switzerland	Large-scale integration of single-nuclei and spatial transcriptomics from the ETOP BEAT-meso trial reveals clinically relevant heterogeneity in malignant pleural mesothelioma 4/20/2026 2:00:00 PM | Integration of Clinical and Research Data Open abstract	Xenium
2754	Haenara Shin, Dongjoo Lee, Jeongbin Park, Hongyoon Choi	Portrai, Inc., Seoul, Korea, Republic of	VGL: Vision-Gene-Language multimodal LLM integrating histopathology and gene expression for cell type classification in lung cancer 4/20/2026 2:00:00 PM | Large Language Models in the Clinic Open abstract	Xenium; Visium
3326	Kazuaki Okamoto, Yalda Naeini, Anton Bilchik, Dave Hoon	Department of Translational Molecular Medicine, St. John’s Cancer Institute (SJCI), Providence St. John's Health Center (PSJHC), Santa Monica, CA | Department of Surgical Pathology, PSJHC, Santa Monica, CA | Department of Gastrointestinal and Hepatobiliary Surgery, PSJHC, Santa Monica, CA	C-myc driven by differentiation factors in early-onset colorectal cancer (EOCRC) 4/20/2026 2:00:00 PM | Tumorigenesis Drivers Open abstract	Xenium
3527	Kang Wang, Ioannis Zerdes, Emmanouil G. Sifakis, Dimitrios Salgkamis, Jonas Bergh, Thomas Hatschek, Alexios Matikas, Theodoros Foukakis	Karolinska Institutet, Stockholm, Sweden	Clonal evolutionary trajectory of HER2-positive breast cancer with ERBB2 or PIK3CA mutations under neoadjuvant treatment 4/20/2026 2:00:00 PM | Tumor Evolution Open abstract	Xenium
3950	Jacob Alltucker, Yiling Shen, Suhyeon Choi, Pavithra Nedumaran, Andrew Martinez, Joseph Lownik, Huihui Ye, Hideki Furuya, Dan Theodorescu, Simon Knott	Cedars-Sinai Medical Center, Los Angeles, CA | Tsinghua University, Beijing, China | University of Arizona, Tucson, AZ	Spatial transcriptomic dissection of microenvironmental drivers of NMIBC progression 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	Xenium
3955	Hassan Brim, Khushi Desai, Shweta Dixi, Justin Hong, Colles Price, Jonathan H. Chen, Nicolas Fernandez, Sara Sim, Sami Farhi, Rabia Zafar, Elham Azizi, Hassan Ashktorab	Howard University, Dist. of Columbia, DC | Columbia, New York, NY | Takeda Pharmaceutical Company Ltd., Deerfield, IN | | Broad, New York, NY	Spatial characterization of tumor-immune interactions in MMR-p and MMR-d among African American colorectal cancer patients using attention-based modeling 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	Xenium
4021	Y.-C. Kao, S. X. Tan, X. Tan, H. Oey, K. J. Lee, T. Vallius, R. Pelletier, A. Causer, C. Zhou, D. Smit, J. O'Neill, A. Xiong, B. O'Brien, A. Collins, P. K. Sorger, H. Soyer, K. Khosrotehrani, Q. Nguyen, M. S. Stark; Frazer Institute, The University of Queensland, Dermatology Research Centre, Brisbane, Australia, QIMR Berghofer Medical Research Institute, Brisbane, Australia, Harvard Medical School, Brookline, MA, Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, Institute for Molecular Bioscience, the University of Queensland, Brisbane, Australia, QIMR Medical Research Institute, Queensland, Australia, Brisbane, Australia, Sullivan Nicolaides Pathology, Brisbane, Australia, Harvard Medical School, Winchester, MA		Precision diagnostics for early melanoma detection using spatial biology and AI guided image analysis 4/20/2026 4:05:00 PM | Biomarkers That Change Management: Predicting Therapy Benefit, Progression, and Metastatic Risk Open abstract	Xenium; Visium
4026	Y. Jiang, W. Yu, S. Pedersen, J. Eagles, A. Thadi, A. Naranjo, N. B. Collins, S. DuBois, R. Bagatell, B. D. Crompton, K. Tan, T. J. Pugh; UHN Princess Margaret Cancer Centre, Toronto, ON, Canada, Children's Hospital of Philadelphia, Philadelphia, PA, University of Florida, Gainesville, FL, Dana-Farber Cancer Institute, Boston, MA, Dana-Farber Cancer Inst., Boston, MA		Spatial T-cell receptor profiling uncovers barriers to T-cell engagement and shared tumor-reactive clonotypes in high-risk neuroblastoma 4/20/2026 3:05:00 PM | Pediatric Cancer from Mechanism to Translation Open abstract	Xenium
4129	Kyungsoo Kim, Soong June Bae, Yoonjin Cha, Yoonwon Kook, Ah Yoon Kim, Jee Hung Kim, Sung Gwe Ahn, Joon Jeong	Yonsei University, Seoul, Korea, Republic of | Gangnam Severance Hospital, Seoul, Korea, Republic of	Spatial single-cell transcriptomic profiling reveals distinct immune and stromal landscapes across TIL/PD-L1-defined TNBC subtypes 4/21/2026 9:00:00 AM | Application of Bioinformatics to Cancer Biology 4 Open abstract	Xenium
4873	Toshio Suzuki, Harry Choi, Erik Johansson, Tetsuharu Nagamoto, Ayako Suzuki, Takuji Suzuki, Katsuya Tsuchihara, Yutaka Suzuki, Yuki Yamamoto	Department of Respirology, Chiba University, Chiba, Japan | HiLung Inc., Kyoto, Japan | Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan | Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan	Reconstructing drug-tolerant persister (DTP) niches in iPSC-derived alveolar lung cancer organoids for spatio-temporal dissection of cell-cell interactions and ligand-receptor targets 4/21/2026 9:00:00 AM | In Vitro Models 2: 2D, 3D, Organoids, and Spheroids Open abstract	Xenium
4945	Ji Hye Choi, Yeong Hak Bang, Kyung Yeon Han, Woong-Yang Park	Sungkyunkwan University, Seoul, Korea, Republic of | University of Ulsan College of Medicine, Seoul | Translational Genomics Center, Seoul, Korea, Republic of | GENINUS, Seoul, Korea, Republic of	Distinct colorectal cancer tumor cell subtypes revealed by single-cell and spatial transcriptomics 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium; Visium
4951	Sanha Hwang	Seoul National University, Seoul, Korea, Republic of	Unraveling the role of APOE/APOC1/SPP1/TREM2‑positive lipid‑Associated macrophages in destructive venous invasion and metastasis of colorectal cancer 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium; GeoMx
4953	Anna Mathioudaki, Zaira Seferbekova, Samuel P. Rutz, Michael Ritter, Domenico Calafato, Gleb Rukhovich, Felix Hinz, Philipp Mahlknecht, Franziska M. Ippen, Ekaterina Popova, Sophia Schinkewitsch, Nela Runa Koeberer, Nina Wilhelm, Pooja Sant, Jan-Philipp Malm, Sascha Dietrich, Christel Herold-Mende, Nima Etminan, Antje Wick, Sandro Krieg, Michael Platten, Andreas von Deimling, Felix Sahm, Abigail Suwala, Moritz Gerstung	AI in Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany | Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany | Department of Hematology, Oncology and Clinical Immunology, Medical Faculty and University Hospital Düsseldorf, Düsseldorf, Germany | Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany | Single Cell Open Lab, German Cancer Research Center (DKFZ), Heidelberg, Germany | Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany | Department of Neurosurgery, University Hospital Mannheim, Medical Faculty Mannheim (UMM), University of Heidelberg, Mannheim, Germany | Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany | Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany | Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Consortium for Translat, German Cancer Research Center (DKFZ), Heidelberg, Germany	Spatial tissue architecture as a unifying principle of tumor and microenvironmental states in adult gliomas 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4956	Jodie Jepson, Kenan Zhang, Anna Corcoran, Elizabeth Owens, Kelly M. Hotchkiss, Beth H. Shaz, Kyra Van Batavia, Jose R. Conejo-Garcia, John Hickey, Mustafa Khasraw	Duke University School of Medicine, Durham, NC | Duke University, Durham, NC | Duke Cancer Institute, Durham, NC	Spatial and vascular microenvironmental features predict tumor-infiltrating lymphocyte expansion in glioblastoma 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4957	Jiayi Fan, Jeffrey Quinn, Wesley Tansey	Computational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY	Spatially resolved profiling of the tumor microenvironment and therapeutic response in SMARCB1-deficient epithelioid sarcoma 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4958	Elana Sverdlik, Jeffrey Quinn, Jiayi Fan, Christopher Tosh, Tamar Feinberg, Melania Franchini, Jovana Pavisic, Shanita Li, Andoyo Ndengu, Glorymar Ibanez Sanchez, Emily Stockfisch, Filemon Dela Cruz, Andrew L. Kung, Joshua Honeyman, Emily Slotkin, Wesley Tansey	Gerstner Sloan Kettering - Graduate School of Biomedical Sciences, New York, NY | Memorial Sloan Kettering Cancer Center, New York, NY | Herbert Irving Comprehensive Cancer Ctr., New York, NY | Chief, Division of Pediatric Hematology/, Memorial Sloan Kettering Cancer Center, New York, NY	Spatial transcriptomic profiling reveals heterogeneity in desmoplastic small round cell tumor 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4960	Bryan Bell, Cedric Uytingco, Alec Barrett, Bryant Ngo, Jonathan Sakkos, Diksha Kool, Wanxin Wang, Melissa del Rosario, Christina Chang, Christina Fan, Andrew Farmer	Takara Bio USA, San Jose, CA	Cross-platform comparison of spatial transcriptomics technologies in an FFPE lung squamous cell carcinoma sample 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium; Visium
4963	Zeinab Mokhtari, Mint Htun, Debayan Mukherjee, Nima Vakili, Deon Hildebrand, Crysthiane Ishiy, Anna Pasto, Sue Griffin, Paul Barber, Tony NG	GSK, Heidelberg, Germany | GSK, Stevenage, United Kingdom	Cross platform validation of spatial domain identification reveals concordant tumor microenvironment architecture in NSCLC using integrated spatial transcriptomics and multiplex immunofluorescence 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4965	Wafaa Bzeih, Yan Tang, Tiegang Han, Andrew J. Sedgewick, Nathan D. Maulding, Carmen Priolo, Katrina Collins, Hadi Mansour, Joelle Chami, Michelle M. Stein, Justin Guinney, Michel Alchoueiry, Jessica F. Williams, Michelle S. Hirsch, Pavlos Msaouel, Elizabeth P. Henske	Department of Medicine, Harvard Medical School/Brigham and Women's Hospital, Boston, MA | Tempus AI, Inc., Chigaco, IL | Indiana University School of Medicine, Indianapolis, IN | Department of Pathology, Harvard Medical School / Brigham and Women's Hospital, Boston, MA | Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX	Sarcomatoid transformation rewires the immune spatial landscape and checkpoint regulation in chromophobe renal cell carcinoma 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4968	Wendell Smith, Elim Cheung, JingHao Tian, Qanber Raza, Toby Astill, Daniel Zangrando, Nina Lane, Tommy Tran, Rikita Gakhar, Vidyodhaya Sundaram	Standard BioTools Inc., South San Francisco, CA | BioChain Institute Inc., Newark, CA	Comprehensive multi-omic profiling of the tumor-immune microenvironment using Xenium transcriptomics and Hyperion XTi Imaging Mass Cytometry 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4986	Sowon Choi, Hee Jin Lee, Byung-Kwan Jeong, Hyun Je Kim	Seoul National University, Seoul, Korea, Republic of | Asan Medical Center, Seoul, Korea, Republic of	Identification of tumor microenvironment for high infiltration of lymphocytes in triple negative breast cancer 4/21/2026 9:00:00 AM | Tumor-Immune Crosstalk Open abstract	Xenium
4995	Yulong Wei, David Alexander Braun, Ya-Chi Ho	Microbial Pathogenesis, Yale School of Medicine, New Haven, CT | Medical Oncology and Hematology, Yale School of Medicine, New Haven, CT	LAMP3+ migratory dendritic cells establish immune-accessible tumor microenvironment in non-Hodgkin lymphoma 4/21/2026 9:00:00 AM | Tumor-Immune Crosstalk Open abstract	Xenium
5265	Yanxia Ma, Nhat Nguyen, Xuehong Gui, Edgardo Aguilar, Luke Connell, Denae Neill, Emil Schüler, Chibawanye I. Ene	Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX	FLASH radiotherapy improves survival in mouse glioblastoma and spares circulating antigen reactive CD8+T-cells 4/21/2026 9:00:00 AM | Effects of Ionizing Radiation on Normal Tissues and FLASH Radiation Research Open abstract	Xenium
5491	Xiangqi Bai, HoJoon Lee, Xiao Tan, Chaoyi Li, Anuja Sathe, Yan Wang, Quan Nguyen, Hanlee P. Ji	Stanford University, Stanford, CA | The University of Queensland, Queensland, Australia	AI foundation model for single cell annotation from conventional histopathology images of cancer 4/21/2026 2:00:00 PM | Machine Learning for Image Analysis Open abstract	Xenium
5496	Mariia Bilous, Daria Buszta, Jonathan Bac, Senbai Kang, Yixing Dong, Stephanie Renaud-Tissot, Sylvie Andre, Marina Alexandre-Gaveta, Christel Voize, Solange Peters, Krisztian Homicsko, Raphael Gottardo	Biomedical Data Science Center, Lausanne University Hospital; University of Lausanne, Lausanne, Switzerland | Department of Oncology, Lausanne University Hospital; Swiss Cancer Center Leman, Lausanne, Switzerland	From transcripts to cells: Dissecting sensitivity, signal contamination, and specificity in Xenium spatial transcriptomics 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium
5499	Xiyu Peng, James Smithy, Mohammad Yosofvand, Caroline Kostrzewa, Fiona Ehrich, MaryLena Bleile, Jasme Lee, Michael A. Postow, Margaret K. Callahan, Katherine Panageas, Ronglai Shen	Texas A&M University, College Station, TX | Memorial Sloan Kettering Cancer Center, New York, NY | Univ. of Connecticut School of Medicine, Farmington, CT	SpatialTopic exploring tumor ecosystem in 3D multiplexed imaging of melanoma 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; CosMx
5519	Junming Shi, Md Tauhidul Islam	Stanford University School of Medicine, Stanford, CA	SOMaC: An interpretable and generalizable framework for integrating and clustering multimodal spatial omics to resolve cell states and immune niches in cancer 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; Visium
5524	Mary Goldman, Brian Craft, Cally Lin, Jingchun Zhu, David Haussler	UC Santa Cruz Genomics Institute, Santa Cruz, CA | Stanford University, San Francisco, CA | Investigator/Distinguished Professor, Ctr. For Bio. Sci. & Eng., UC Santa Cruz, Santa Cruz, CA	Visualization and analysis of cancer genomics data using UCSC Xena 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; Visium; Chromium; CosMx; MerFISH
6051	Myriam Iliana Ibanez Rios, Maëlle Batardiere, Alexandre Archambault-Marsan, Elham Dianati Ajibisheh, Vincent Quoc-Huy Trinh, David J.H F. Knapp	Institute for Research in Immunology and Cancer (IRIC), Montréal, QC, Canada	Pancreatic tumor expressed growth factors activate a neural-like program in human fibroblasts which is associated with poor prognosis 4/21/2026 2:00:00 PM | Fibroblasts as Architects of the Tumor Microenvironment Open abstract	Xenium
6113	Yufei Wang, Jae-Won Cho, Yasmin Nabil Laimon, Wenxin Xu, Kun Huang, Aseman Bagheri Sheshdeh, Nithyassree Murugan, Hsien-Chi Yuan, Jon Wee, David Alexander Braun, Toni K. Choueiri, Catherine J. Wu, Sabina Signoretti, Gordon J. Freeman, Martin Hemberg, Wayne A. Marasco	Dana-Farber Cancer Institute, Boston, MA | Brigham and Women's Hospital, Boston, MA | Yale School of Medicine, New Haven, CT | Associate Professor, Dana-Farber Cancer Institute, Boston, MA	ccRCC lung metastases harbor cancer associated fibroblast lymphocyte exclusion sites that form a confined TME as revealed by single cell and spatial multi-omics 4/21/2026 2:00:00 PM | Metastasis and Organ-Specific Microenvironmental Evolution Open abstract	Xenium; CosMx
6118	Junghan Oh, Hoyeon Jeong, Yoon La Choi, Donggun Lee, Misook Lee	Samsung Advanced Institute of Technology, Seoul, Korea, Republic of | Samsung Advanced Institute for Health Sciences and Technology, Seoul, Korea, Republic of	Spatially resolved SEED (stromal-enriched metastatic decider) niches integrate tumor, stromal, and immune ecosystems to enable lymph node dissemination in LUAD 4/21/2026 2:00:00 PM | Metastasis and Organ-Specific Microenvironmental Evolution Open abstract	Xenium
6159	Ping Xu, Yuehui Zhao, Yun Yan, Rui Ye, Chenling Tang, Emi Sei, Shanshan Bai, Tuan Tran, Cole Ruoff, Christine Ly, Keyi Zhu, Miao Zhang, Bila A. Siddiqui, Sumit K. Subudhi, Paul Corn, Christopher J. Logothetis, Patricia Troncoso, Amado J. Zurita-Saavedra, Nicholas Navin	Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX | Department of Pathology, UT MD Anderson Cancer Center, Houston, TX | Department of Genitourinary Medical Oncology, UT MD Anderson Cancer Center, Houston, TX	Co-evolution of cancer cells and their microenvironment of primary and lymph node metastatic prostate cancer under androgen deprivation therapy 4/21/2026 2:00:00 PM | Metastatic Niches and Microenvironment Open abstract	Xenium; Visium
6188	Yun Yan, Yiyun Lin, Tapsi Kumar, Shanshan Bai, Aatish Thennavan, Jianzhuo Li, Tuan Tran, Min Hu, Mitchell Rao, Anna Casasent, Elizabeth Ravenberg, Gaiane Margishvili Rauch, Alyson Clayborn, Debu Tripathy, Alastair Thompson, Bora Lim, Lei Huo, Lei Huo, Stacy Moulder, Clinton Yam, Nicholas E. Navin	UT MD Anderson Cancer Center, Houston, TX | Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, TX	Decoding the archetypes and ecotypes of triple-negative breast cancer in responses to chemotherapy 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium; Visium
6189	Nora M. Lawson, Inés Martín-Barrio, Lingqun Ye, Bo Zhao, Thomas Mitchell, Mesut Unal, Chae Yun Cho, Andrew Futreal, Kadir C. Akdemir	Neurosurgery, UT MD Anderson Cancer Center, Houston, TX | Genetics, UT MD Anderson Cancer Center, Houston, TX | Genomic Medicine, UT MD Anderson Cancer Center, Houston, TX	ERBB2 expression and the immune landscape shape the tumor microenvironment and influence prognosis in esophageal adenocarcinoma brain metastases 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium
6194	Harim Chun, Yeoun Eun Sung, Sook Hee Hong, Sangjeong Ahn, Sung Hak Lee	Department of Medical Science, Graduate School, The Catholic University of Korea, Seoul, Korea, Republic of | Department of Hospital Pathology, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea, Republic of | Division of Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of | Department of Pathology, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, Korea, Republic of	Spatial architecture of immunochemotherapy response in pleural mesothelioma 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium
6195	Heng Luo, Clémence Henon, Gleb Rukhovich, Stefanie Kutschmann, Nina Wilhelm, Wolfgang Hartmann, Uta Dirksen, Duncan T. Odom, Thomas G. Grünewald, Moritz Gerstung	Division of Artificial Intelligence in Oncology, DKFZ German Cancer Research Center, Heidelberg, Germany | Division of Translational Pediatric Sarcoma Research, DKFZ German Cancer Research Center, Heidelberg, Germany | Gerhard-Domagk-Institute of Pathology, Münster University Hospital, Muenster, Germany | Pediatrics III, University Hospital Essen, West German Cancer Center, NCT West, Essen, Germany | Division of Regulatory Genomics and Cancer Evolution, DKFZ German Cancer Research Center, Heidelberg, Germany	Spatial transcriptomics analysis reveals tumor cell plasticity and diverse tumor microenvironments in Ewing sarcoma 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium
6205	Tommy Tran, JingHao Tian, Elim Cheung, Rikita Gakhar, Vidyodhaya Sundaram	BioChain Institute, Inc., Newark, CA	Establishing reproducibility standards for Xenium spatial transcriptomics through multi-replicate validation and cross-sectional analysis 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium
6212	Julia Louw, Kenan Zhang, Anna Corcoran, Elizabeth Owens, Jodie Jepson, Jose R. Conejo-Garcia, David M. Ashley, Kanish Mirchia, David R. Raleigh, Mustafa Khasraw	Duke University, Durham, NC | Duke University School of Medicine, Durham, NC | Duke University Medical Center, Durham, NC | UCSF, San Francisco, CA | University of California San Francisco, San Francisco, CA | Duke Cancer Institute, Durham, NC	Spatial immune and vascular remodeling defines recurrence in oligodendroglioma 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium; Visium
6447	Serena Zheng, Jason Link, Alykhan Premji, Michael Srienc, McKensie Hammons, Shineui Kim, David Dawson, Zev Wainberg, Timothy Donahue	Surgery, UCLA Medical Center, Los Angeles, CA | UCLA David Geffen School of Medicine, Los Angeles, CA | Pathology, UCLA Medical Center, Los Angeles, CA | Medicine, UCLA Medical Center, Los Angeles, CA	FOLFIRINOX plus nivolumab promotes plasma cell production from intra-tumoral lymphoid aggregates in borderline resectable pancreatic adenocarcinoma 4/21/2026 2:00:00 PM | Biostatistics in Clinical Trials / Surgical Oncology Open abstract	Xenium
6449	Michael K. Srienc, Serena Zheng, Jason Link, Alykhan Premji, McKensie Hammons, Shineui Kim, Evan Abt, Caius G. Radu, David W. Dawson, Zev A. Wainberg, Timothy R. Donahue	UCLA Health, Los Angeles, CA | UCLA Dept of Surgery, Los Angeles, CA | UCLA David Geffen School of Medicine, Los Angeles, CA | UCLA Medical Center Santa Monica, Santa Monica, CA | Assistant Professor, Dept. of General Surg., UCLA David Geffen School of Medicine, Los Angeles, CA	Adenosine blockade combined with FOLFIRINOX chemotherapy enhances T follicular helper cell function in pancreatic adenocarcinoma draining lymph nodes from mice and humans 4/21/2026 2:00:00 PM | Biostatistics in Clinical Trials / Surgical Oncology Open abstract	Xenium
6478	KyuTae Hwang, Seowoo Kim, Mi Zhou, William Y. Kim, Minyong Kang	Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology (SAIHST), Seoul, Korea, Republic of | UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC | UNC Chapel Hill, Cary, NC | Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology (SAIHST)Samsung Medical Center, Seoul, Korea, Republic of	Temporal dynamics of T cell reprogramming associate with clinical response to ICI-based combination therapy in metastatic renal cell carcinoma 4/21/2026 2:00:00 PM | Clinical Correlates of Immunotherapy Open abstract	Xenium
6573	Paula O. Cooper, Laila N. Scroggins, Sally Elsamanoudi, Amina Ali, Picabo Binette, Beatriz German Falcon, Leigh Ellis, Gregory T. Chesnut, Shyh-Han Tan, Cara C. Schafer	Surgery, Center for Prostate Disease Research, Bethesda, MD	Assessment of the T cell receptor repertoire in racially diverse prostate cancer patients 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	Xenium
6576	Chih-Hung Chung, Han-Hsun Yu, Muh-Hwa Yang	National Yang Ming Chiao Tung University, Taipei, Taiwan	Integrative spatial transcriptomics reveals EMT-driven immune regulatory programs underlying metastasis in HNSCC 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	Xenium; Visium; GeoMx
6662	Maryam Ranjpour, Mohamed Omar	Cedars-Sinai Medical Center, Los Angeles, CA	Spatial genomics reveals microenvironmental programs associated with organ-specific metastatic propensity in prostate cancer 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	Xenium
6663	Qanber Raza, Nick Zabinyakov, Lauren Tracey, Liang Lim, Christina Loh	Standard BioTools, Markham, ON, Canada	Integrated spatial transcriptomic and proteomic profiling reveals tumor-immune niches driving heterogeneity and resistance in clear cell renal cell carcinoma 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	Xenium
6667	Cindy Pamela Ulloa Guerrero, Michele Bortolomeazzi, Pooja Sant, Laura Schütze, Laura Giese, Denise Keitel, Julia Boehl, Robin Reschke, Jan-Philipp Mallm	Single-cell Open Lab, DKFZ German Cancer Research Center, Heidelberg, Germany | Max-Eder Research Group Reschke, University Hospital Heidelberg, Heidelberg, Germany	Integrated spatial transcriptomics and proteomics workflows for high-resolution multiomics analysis 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	Xenium; Visium
6741	M. Li, X. Hoi, J. Deng, J. Zheng, R. Hashmani, R. Bayraktar, W. Qian, J. Zhou, J. Guan, K. Sun, H. Mai, T. Sheu, S. Haley, M. Schwartz, S. Mathur, S. T. Wong, F. Nikolo, K. Chan, P. Niravath, J. C. Chang; Houston Methodist Research Institute, Houston, TX, Houston Methodist Hospital, Houston, TX		Tertiary lymphoid structure (TLS)-associated immune circuits define response to durvalumab, trastuzumab, and pertuzumab (DTP) in HER2-enriched early breast cancer 4/21/2026 2:50:00 PM | Immunotherapy: Mechanisms and Responses Open abstract	Xenium
6759	P. Kerwin, L. Zanella, A. Califano; Columbia University, New York, NY		High-throughput drug screening and single-cell network analysis identify rational combination therapies in IDH-mutant glioma 4/21/2026 2:50:00 PM | Targeted Therapy: Data Driven Approaches and Novel Drugs Open abstract	Xenium
6788	B. Zhu, M. Aminu, Y. Tian, S.-W. Lu, O. Shi, W. Lu, H. Chen, H. Li, Z. Wei, M. B. Nilsson, L. Solis Soto, F. P. Andrew, D. L. Gibbons, J. V. Heymach, C. Cheng, J. Wu, J. Zhang; UT MD Anderson Cancer Center, Houston, TX, The University of Texas MD Anderson Cancer Center, Baylor College of Medicine, Houston, TX		Spatial single-cell analysis reveals stage-dependent mechanisms of anti-IL-1β therapy in lung adenocarcinoma 4/21/2026 3:20:00 PM | Inflammation and Immunity in Cancer Progression Open abstract	Xenium; Visium
6797	M. Wang, A. Sabet, S. Rakhade, E. Spanos, L. Morrill Gavarró, R. Giri, P. Manoj, H. A. Yu, A. Quintanal-Villalonga, J. T. Poirier, E. Redin, D. Pe'er, C. M. Rudin, J. M. Chan; Memorial Sloan Kettering Cancer Center, New York, NY, Herbert Irving Comprehensive Cancer Ctr., New York, NY, NYU Langone Health Perlmutter Cancer Ctr., Brooklyn, NY		Basal-state origins and genotype-specific trajectories of neuroendocrine plasticity in lung cancer 4/21/2026 3:35:00 PM | Genomic Approaches to Understanding Tumor Evolution Open abstract	Xenium
6837	Jeongbin Park, Tingrui Zhang, Cong Ma	University of Michigan, Ann Arbor, MI	Scalable cell type and spatial domain modeling using spatially informed topic inference of cancer niches 4/22/2026 9:00:00 AM | Mathematical Modeling and Statistical Methods Open abstract	Xenium
6853	Xiao Wang, Nan Zhang, Chi Zhang, Sha Cao	Indiana University, Bloomington, IN | Fudan University, Shanghai, China | Knight Cancer Institute, Oregon Health & Science University, Portland, OR | Biomedical Engineering, Oregon Health and Science University, Portland, OR	A segmentation-free method for modeling high-resolution spatial transcriptomics at the molecule level 4/22/2026 9:00:00 AM | Mathematical Modeling and Statistical Methods Open abstract	Xenium; Visium
6858	Luca Zanella, Patrick M. Kerwin, Mikko Turunen, Peter A. Sims, Peter D. Canoll, Andrea Califano	Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, New York, NY | Department of Systems Biology and Department of Biochemistry and Molecular Biophysics, Columbia University Irving Medical Center, New York, NY | Department of Pathology and Cell Biology and Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY | Dept. of Systems Biology and Dept. of Medicine and Dept. of Biomedical Informatics and Dept. of Biochemistry & Molecular Biophysics, and HICCC, Columbia University Irving Medical Center; Chan Zuckerberg Biohub, New York, NY	Single-cell elucidation of molecularly distinct states and therapeutic vulnerabilities in IDH-mutant glioma 4/22/2026 9:00:00 AM | Network Biology and Precision Medicine Open abstract	Xenium
6859	Melania Franchini, Florencia Picech, Cory Abate-Shen, Andrea Califano	Department of Systems Biology, Columbia University, New York, NY | Department of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, NY | Department of Molecular Pharmacology and Therapeutics, Department of Urology, Columbia University Irving Medical Center, New York, NY | Dept. of Systems Biology and Dept. of Medicine and Dept. of Biomedical Informatics and Dept. of Biochemistry & Molecular Biophysics, and HICCC, Columbia University Irving Medical Center; Chan Zuckerberg Biohub, New York, NY	Targeting master regulators to reprogram neutrophils and enhance PD-1 blockade efficacy in castration-resistant prostate cancer 4/22/2026 9:00:00 AM | Network Biology and Precision Medicine Open abstract	Xenium
6895	Yufeng He, Yanping Zhao, Rui Zhang, Heli Yang, Zhaode Bu, Yuan Luo, Deng Pan, Zexian Zeng	Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China | Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China | Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Peking University, Beijing, China | Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL | Tsinghua-Peking Center for Life Sciences, Department of Basic Medical Sciences, Tsinghua University, Beijing, China	DISSECT integrates cytological images and spatial transcriptomics for cell segmentation 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	Xenium; Visium; CosMx
6909	Jinghao Tian, Tommy Tran, Elim Cheung, Rikita Gakhar, Vidyodhaya Sundaram	Johns Hopkins University, Baltimore, MD | BioChain Institute, Inc., Newark, CA	Dimensionless, null-calibrated spatial indices from Xenium RNA and protein in breast IDC and lung adenocarcinoma 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	Xenium
6914	Xinyu Hu, Fengwei Zhan, Lixia C. Wu, Jose Gonzalez, Chuhanwen Sun, Rachel Ofer, Tyler Tran, Michael Verzi, Jiekun Yang	Department of Genetics, Rutgers University, New Brunswick, NJ | Quantitative Biomedicine Program, Rutgers University, New Brunswick, NJ	STCS: Spatial transcriptomics cell segmentation outperforms existing methods on multiple slides 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	Xenium; Visium
6995	Susrutha Puthanmadhom Narayanan, Chien-Wei Peng, Adrienne Visani, Xiangwei Fang, Andre Luiz N. Targino da Costa, Jingxian Liu, Reyka G. Jayasinghe, Ambrose Plante, John M. Herndon, Jacqueline Mudd, Preet Lal, Wagma Caravan, Kapur B. Dhami, Jennifer Ponce, Robert S. Fulton, Michael Heinz, Milan G. Chheda, Feng Chen, Michael Iglesia, Ryan C. Fields, Li Ding	Washington University in St. Louis, St. Louis, MO | Washington University School of Medicine in St. Louis, St. Louis, MO	Spatial immune landscape in metastatic colorectal cancer 4/22/2026 9:00:00 AM | Tumor-induced Immune Suppression Open abstract	Xenium
7436	Kathryn H. Gessner, Jeffrey S. Damrauer, Siyao Liu, Mi Zhou, David Corcoran, Sara E. Wobker, William Kim	UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC	Dissecting the spatial architecture of plasmacytoid urothelial carcinoma to inform therapeutic strategies 4/22/2026 9:00:00 AM | Microenvironmental Determinants of Therapy Response and Resistance 2 Open abstract	Xenium
7514	Yize Li, Wagma Caravan, Xiyi Wei, Kapur B. Dhami, Kazuhito Sato, Xiangwei Fang, Preet Lal, Hongyi Liu, Lijun Chen, Cody Weimholt, Hui Zhang, Li Ding, Feng Chen	Washington University in St. Louis, Saint Louis, MO | Johns Hopkins University, Baltimore, MD	Spatial multimodal and functional dissection reveal a UCHL1-driven malignant program in clear cell renal cell carcinoma 4/22/2026 9:00:00 AM | Tumor Heterogeneity Open abstract	Xenium
7641	Abel Martel-Martel, Nan Deng, Melissa W. Taggart, Araceli Garcia-Gonzalez, Jacklyn V. Thompson, Luigi Ricciardiello, Y. Nancy You, Selvi Thirumurthi, Krishna M. Sinha, Eduardo Vilar	Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX | Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX | Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX | Colorectal Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX	Decoding the spatial architecture of the immune microenvironment in mismatch repair-deficient colorectal carcinogenesis 4/22/2026 9:00:00 AM | Cancer and Cancer Related Alterations, Detection Approaches, and Molecular Characterization Open abstract	Xenium
7743	Maxime Meylan, Ye Tian, Lijian Wu, Alexander L. Ling, Daniel Kovarsky, Graham L. Barlow, Linh D. Nguyen, Jason Pyrdol, Lucas Westphal, Michel Julius, Nicolas L. Gonzalez Castro, Sydney D. Dumont, Andres Santos, Itay Tirosh, Mario L. Suva, E Antonio Chiocca, Kai W. Wucherpfennig	Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA | Harvey Cushing Neuro-oncology Laboratories, Department of Neurosurgery and Center for Tumors of the, Mass General Brigham Cancer Institute, Boston, MA | Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel | Department of Pathology and Krantz Family Center for Cancer Research, Massachusetts General Hospital, Boston, MA	Pre-existing T cells drive durable anti-tumor immunity after oncolytic virus therapy in glioblastoma 4/22/2026 9:00:00 AM | Immune Response to Therapies Open abstract	Xenium
7775	Michelle Kinder, Rui Hong, Chifei Sun, Yunlan Fang, Michael Smith, Cynthia Timmers, Chiara Greggio, Jordi Rodon Ahnert	Incyte Corporation, Wilmington, DE | The University of Texas MD Anderson Cancer Center, Houston, TX	Pharmacodynamic biomarkers of TGFβR2xPD-1 bispecific antibody INCA33890 in patients with MSS metastatic colorectal cancer (mCRC) 4/22/2026 9:00:00 AM | Immunomodulatory Agents and Interventions Open abstract	Xenium
CT188	Moran Amit, Robert Saddawi-Konefka, Shorook Naara, Fred Netto, Fred Netto, Chen F Fushun, Yen Vu, Sophie Li, Tongxin Xie, Shamima Akhter, Hinduja Sathishkumar, Tieling Zhou, Sreyashi Basu, Luana Sousa, Neal Akhave, Theresa Hofstede, Ann Gillenwater, Ed Diaz, Kirsten Pytynia, Lorena Gomez, Michelle Williams, Andrew Sikora, Jeffrey Myers, Humam Kadara, James Allison, Sharma Padmaneee, Mark Chambers	UT MD Anderson Cancer Center, Houston, TX	Intralesional PD-1 blockade for oral cancer prevention: First-in-class phase 1 trial 4/21/2026 9:00:00 AM | Phase I Clinical Trials Open abstract	Xenium
LB123	Anna Vila-Escoda, Marta Piqué-Gili, Marta Casado-Pelaez, Roser Pinyol, Ana Hernández de Sande, Verónica Davalos, Albert Gris-Oliver, Carla Montironi, Judit Peix, Daniela Grases, Ezequiel Mauro, Guillem Cano-Segarra, Sarah Cappuyns, Igor Figueiredo, Giorgio Ioannou, Edgar Gonzalez-Kozlova, Tim Meyer, Anja Lachenmayer, Jens U Marquardt, Helen L Reeves, Julien Edeline, Fabian Finkelmeier, Jörg Trojan, Sacha Gnjatic, Jean-Frederic Blanc, Richard A Hubner, Matthias Pinter, Tom Luedde, Arndt Vogel, Daniela Sia, Vincenzo Mazzaferro, Manel Esteller, Jeroen Dekervel, Eduard Porta-Pardo, Josep M Llovet	Liver Cancer Translational Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona. Mount Sinai Liver Cancer Program, Divisions of Liver Diseases, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY | Cancer Epigenetics Group, Josep Carreras Leukaemia Research Institute (IJC), IJC Building, Germans Trias I Pujol, Barcelona, Spain | Liver Cancer Translational Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona, Spain | Liver Cancer Translational Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic; Pathology Department and Molecular Biology Core, Hospital Clínic of Barcelona, Barcelona, Spain | Josep Carreras Leukemia Research Institute (IJC), Barcelona, Spain | Liver Cancer Translational Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Barcelona, Spain | Digestive Oncology, Department of Gastroenterology, University Hospitals Leuven, Leuven, Belgium | Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY | Research Department of Oncology, UCL Cancer Institute, University College London, Royal Free Hospital, London, United Kingdom | Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland | Department of Medicine I, University Medical Center Schleswig Holstein Campus Lübeck, Lübeck, Germany | Newcastle University Translational Research Institute, Newcastle upon Tyne NHS Foundation Trust, and NIHR Newcastle Biomedical Research Centre, Newcastle, United Kingdom | Department of Medical Oncology, Centre Eugène Marquis, Rennes, France | Department of Gastroenterology, University Liver and Cancer Centre, Frankfurt, Germany | Department of Hepatogastroenterology and Medical Oncology, CHU de Bordeaux Hôpital Haut-Lévêque, Pessac, France | Department of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester, United Kingdom | Division of Gastroenterology and Hepatology, Department of Medicine, Medical University of Vienna, Vienna, Austria | Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Dusseldorf, Medical Faculty at Heinrich Heine University Dusseldorf, Dusseldorf, Germany | Hannover Medical School, Hannover, Austria | Mount Sinai Liver Cancer Program, Divisions of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY | Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy; HPB Surgery, Hepatology and Liver Transplantation, Fondazione IRCCS Istituto Nazionale Tumori di Milano, Milan, Italy | Josep Carreras Leukemia Research Institute (IJC).Centro de Investigacion Biomedica en Red Cancer. Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain | Department of Gastroenterology and Hepatology, University Hospitals KU Leuven, Leuven, Belgium | Josep Carreras Leukemia Research Institute (IJC). Barcelona Supercomputing Center (BSC), Barcelona, Spain	Spatial immune architecture at single-cell resolution predicts response to atezolizumab plus bevacizumab in advanced HCC 4/20/2026 9:00:00 AM | Late-Breaking Research: Clinical Research 2 Open abstract	Xenium
LB199	Praveen Bhoopathi, Khoa L. A. Huynh, Erica J. Peterson, Vashti Bandy, Anna Gibson, Vignesh Vudatha, Arunima Punjala, Dongyu Zhang, Jinze Liu, J Chuck Harrell, Nicholas P. Farrell, Jose G. Trevino	Dept of Surgery, Massey Comprehensive Cancer Center, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Biostatistics, Massey Comprehensive Cancer Center, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Internal Medicine, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Surgery, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Pathalogy, Massey Comprehensive Cancer Center, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Chemistry, Virginia Commonwealth University- VCU, Richmond, VA	High-plex spatial transcriptomics reveals triplatin-induced DNA damage signaling and tumor-fibroblast niche reprogramming in pancreatic cancer PDX models 4/20/2026 2:00:00 PM | Late-Breaking Research: Experimental and Molecular Therapeutics 2 Open abstract	Xenium
LB237	Wei Zhao, Aaron Rozeboom, Phuc H. Hoang, Tam-Anh Tran, Maria Teresa Landi	National Cancer Inst. Div. of Cancer Epidemiology & Genetics, Bethesda, MD | Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD	High-resolution spatial transcriptomics identifies unique spatial programs in lung adenocarcinoma from never smokers 4/20/2026 2:00:00 PM | Late-Breaking Research: Tumor Biology 1 Open abstract	Xenium; Visium
LB302	Eva Zhao, Isam Adam, Angela Lincy Prem Antony Samy, Jacob Insua-Rodríguez, Pascal Naef, Sharmila Mallya, Jenny Wu, Delia F. Tifrea, Robert A. Edwards, Ahmed Mohyeldin, Devon A. Lawson	University of California, Irvine, Irvine, CA	Investigation of the immune microenvironment of breast cancer brain metastasis using single-cell spatial genomics 4/21/2026 9:00:00 AM | Late-Breaking Research: Tumor Biology 2 Open abstract	Xenium
LB423	Marc Hilmi, Wilson Mckerrow, Joshua D. Schoenfeld, Shigeaki Umeda, Nuray Tezcan, Catherine O'Connor, Yuval Elhanati, Charlotte Reiche, Martina Milighetti, Mara Sherman, Elias-Ramzey Karnoub, Roshan Sharma, Vincenzo Nasca, Kevin Soares, Zeynep Tarcan, Jerry Melchor, Olca Basturk, Nadeem Riaz, Nicolas Lecomte, Vinod P. Balachandran, Dana Pe’er, Benjamin D. Greenbaum, Christine A. Iacobuzio-Donahue, Eileen M. O'Reilly, Wungki Park	Memorial Sloan Kettering Cancer Center, New York, NY	Invigorating pre-existing tumor-infiltrating expandable (TIE) T cell clonotypes in exceptional responders with dual PARP-PD-1 blockade in homologous recombination deficient (HRD) pancreatic cancer 4/22/2026 9:00:00 AM | Late-Breaking Research: Clinical Research 4 Open abstract	Xenium

Abstract #	Authors	Affiliation	Title / Session	Products
1201	Yunhe Liu, Idania Carolina Lubo Julio, Wei Lu, Alejandra G. Serrano, Jean R. Clemenceau, Amber Famiglietti, Karen Colbert, Yibo Dai, Yang Liu, Jun Wang, Jeremy L. Davis, Mingyao Li, Paul F. Mansfield, Tae Hyun Hwang, Luisa M. Solis-Soto, Linghua Wang	Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Surgery, Vanderbilt University Medical Center, Nashville, TN | National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD | Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX | BioChemistry&Molecular Biology, University of Maryland School of Medicine, Baltimore, MD | University of Pennsylvania, Philadelphia, PA | Vice President, Acute Care Services, UT MD Anderson Cancer Ctr., Houston, TX | Department of Translational Molecular Pathology, the university of MD Anderson cancer center, Houston, TX	Spatial 3D and multi-omics mapping of diffuse gastric cancer evolution from preinvasive to invasive lesions in CDH1 mutation carriers 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium; CosMx; GeoMx; G4X
1203	Tian Chu, Jimin Min, Yunhe Liu, Yang Liu, Yibo Dai, Kyung Serk Cho, Xueshuai Han, Kai Yu, Fuduan Peng, Anirban Maitra, Humam Kadara, Linghua Wang	Genomic Medicine, UT MD Anderson Cancer Center, Houston, TX | Medicine, New York University Grossman School of Medicine, New York, NY | UT MD Anderson Cancer Center, Houston, TX | Department of Pathology, New York University Grossman School of Medicine, New York, NY	Spatial archetypes of conserved and cancer-specific immune-stromal niches 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium
1208	Mitsuho Imai, Eun Seop Seo, Jiyeon Hyeon, Shingo Sakashita, Yuka Nakamura, Tadayoshi Hashimoto, Shin Kobayashi, Jun Yuda, Riu Yamashita, Taro Shibuki, Takao Fujisawa, Masataka Amisaki, Kensuke Matsuda, Shun-ichiro Kageyama, Michiko Nagamine, Takeshi Kuwata, Hideaki Bando, Woong-Yang Park, Takayuki Yoshino	National Cancer Center Hospital East, Kahsiwashi, Japan | GxD Inc, Seoul, Korea, Republic of | GxD Inc, Kashiwashi, Japan | National Cancer Center Hospital East, Kashiwashi, Japan | National Cancer Center Hospital East, Kashiwanoha, Japan | Pathology, NCCHE, Kashiwa, Japan | National Cancer Center Hospital East, Kashiwa, Japan	The MONSTAR-SCREEN-3 Spatial Atlas: Pan-cancer TME archetypes and clinically relevant tumor-immune ecosystems 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium
1223	Nicholas E. Bingham, Julie R. Boiko, Daniel C. Jones, Daniel Wong, Tiffany Khong, Sridurga Mithraprabhu, Kathleen S. Ensbey, Anna E. Elz, Evan W. Newell, Andrew Spencer, Geoffrey R. Hill	Australian Centre for Blood Diseases, Alfred Health - Monash University, Melbourne, Australia | Translational Science and Therapeutics Division, Fred Hutchison Cancer Centre, Seattle, WA | Vaccine and Infectious Diseases Division, Fred Hutchison Cancer Centre, Seattle, WA | Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Centre, Seattle, WA	Spatial transcriptomics identifies a suppressive T-cell excluded tumour microenvironment in extramedullary multiple myeloma 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium
1484	Yongjoon Jin, Jeong-Yeon Ji, Hyojung Lee, Na-yeon Kim, Eun-Jae Chung, Jong-Il Kim	Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Korea, Republic of | Department of Otorhinolaryngology-Head and Neck Surgerys, Seoul National University Bundang Hospital, Gyeonggi-do, Korea, Republic of | Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Korea, Republic of | SNU Medicine, Seoul, Korea, Republic of	p-EMT transitional hub and its DC2-macrophage niche define recurrence in oral squamous cell carcinoma 4/20/2026 9:00:00 AM | Integrative Computational Approaches 1 Open abstract	Xenium
2253	Fushun Chen, Lorena Isabel Gomez, Tieling Zhou, Yuejiang Liu, Inti C. Tarifa Reischle, Sujuan Yang, Manvi Sharma, ,Jiping Feng, Jaafar Hadi, Fuduan Peng, Yibo Dai, Mhenaz Hossain, Ratna Veeramachaneni, Ansam Sinjab, Sean Anderson, Dhrishit Mangrolia, Deborah Rodriguez, Nadim Ajami, Jennifer Wargo, Adel El-Naggar, Roberto Rangel, Nadarajah Vigneswaran, Linghua Wang, Jeffrey N. Myers, Humam Kadara	UT MD Anderson Cancer Center, Houston, TX | UT Health School of Dentistry, Houston, TX	Multimodal and multikingdom spatial transcriptomics identify bacterial niches implicated in oral cancer development 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2255	Yibo Dai, Fuduan Peng, Ansam Sinjab, Yunhe Liu, Sujuan Yang, Lorena I Gomez Bolanos, Tieling Zhou, Minyue Chen, Alejandra G Serrano, Jianlong Liao, Guangsheng Pei, Yang Liu, Jiahui Jiang, Kyung Serk Cho, Kai Yu, Jiping Feng, Zahraa Rahal, Naoe Jimbo, Takuo Hayashi, Satsuki Kishikawa, Kazuya Takamochi, Avrum Spira, Steven M. Dubinett, Tomoo Itoh, Takashi Yao, Kenji Suzuki, Stephen G. Swisher, Mingyao Li, Junya Fujimoto, Ignacio Wistuba, Jared K. Burks, Kadir Caner Akdemir, Hind Rafei, Katayoun Rezvani, Jeffrey N. Myers, Humam Kadara, Linghua Wang	UT MD Anderson Cancer Center, Houston, TX | Kobe University Hospital, Kobe, Japan | Juntendo University Graduate School of Medicine, Tokyo, Japan | Lung Cancer Initiative at Johnson and Johnson, Boston, MA | UCLA David Geffen School of Medicine, Los Angeles, CA | University of Pennsylvania, Philadelphia, PA | Hiroshima University Hospital, Hiroshima, Japan | Moffitt Cancer Center & Research Institute, Tampa, FL	Spatial transcriptomics reveals evolving tumor microenvironmental archetype along the lung premalignancy-adenocarcinoma continuum 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2272	Akifumi Mochizuki, Ayako Suzuki, Kouya Shiraishi, Masahiro Torasawa, Takayuki Honda, Susumu Kirimura, Yasunari Miyazaki, Kenichi Okubo, Syuzo Kaneko, Yukihiro Yoshida, Shun-ichi Watanabe, Masahiro Tsuboi, Genichiro Ishii, Issei Imoto, Ryuji Hamamoto, Yasushi Yatabe, Yutaka Suzuki, Takashi Kohno	Department of Respiratory Medicine, Institute of Science Tokyo, Tokyo, Japan | Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan | National Cancer Center Research Institute, Tokyo, Japan | Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan | Division of Pathology, Institute of Science Tokyo, Tokyo, Japan | Department of Thoracic Surgery, Institute of Science Tokyo, Tokyo, Japan | Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan | Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan | Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan | Department of Pathology and Clinical laboratories, National Cancer Center Hospital East, Kashiwa, Japan | Dept. of Human Genetics, Inst. of Health Biosciences, Aichi Cancer Center Research Institute, Nagoya, Japan | Associate Professor, National Cancer Center Japan, Tokyo, Japan | Chief, Dept. of Pathology & Molec. Diagnostics, National Cancer Center, Nagoya, Japan	Dichotomous immunogenetic landscape of lung adenocarcinoma associated with usual interstitial pneumonia 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
3527	Kang Wang, Ioannis Zerdes, Emmanouil G. Sifakis, Dimitrios Salgkamis, Jonas Bergh, Thomas Hatschek, Alexios Matikas, Theodoros Foukakis	Karolinska Institutet, Stockholm, Sweden	Clonal evolutionary trajectory of HER2-positive breast cancer with ERBB2 or PIK3CA mutations under neoadjuvant treatment 4/20/2026 2:00:00 PM | Tumor Evolution Open abstract	Xenium
3955	Hassan Brim, Khushi Desai, Shweta Dixi, Justin Hong, Colles Price, Jonathan H. Chen, Nicolas Fernandez, Sara Sim, Sami Farhi, Rabia Zafar, Elham Azizi, Hassan Ashktorab	Howard University, Dist. of Columbia, DC | Columbia, New York, NY | Takeda Pharmaceutical Company Ltd., Deerfield, IN | | Broad, New York, NY	Spatial characterization of tumor-immune interactions in MMR-p and MMR-d among African American colorectal cancer patients using attention-based modeling 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	Xenium
4873	Toshio Suzuki, Harry Choi, Erik Johansson, Tetsuharu Nagamoto, Ayako Suzuki, Takuji Suzuki, Katsuya Tsuchihara, Yutaka Suzuki, Yuki Yamamoto	Department of Respirology, Chiba University, Chiba, Japan | HiLung Inc., Kyoto, Japan | Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan | Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan	Reconstructing drug-tolerant persister (DTP) niches in iPSC-derived alveolar lung cancer organoids for spatio-temporal dissection of cell-cell interactions and ligand-receptor targets 4/21/2026 9:00:00 AM | In Vitro Models 2: 2D, 3D, Organoids, and Spheroids Open abstract	Xenium
4951	Sanha Hwang	Seoul National University, Seoul, Korea, Republic of	Unraveling the role of APOE/APOC1/SPP1/TREM2‑positive lipid‑Associated macrophages in destructive venous invasion and metastasis of colorectal cancer 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium; GeoMx
4957	Jiayi Fan, Jeffrey Quinn, Wesley Tansey	Computational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY	Spatially resolved profiling of the tumor microenvironment and therapeutic response in SMARCB1-deficient epithelioid sarcoma 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4958	Elana Sverdlik, Jeffrey Quinn, Jiayi Fan, Christopher Tosh, Tamar Feinberg, Melania Franchini, Jovana Pavisic, Shanita Li, Andoyo Ndengu, Glorymar Ibanez Sanchez, Emily Stockfisch, Filemon Dela Cruz, Andrew L. Kung, Joshua Honeyman, Emily Slotkin, Wesley Tansey	Gerstner Sloan Kettering - Graduate School of Biomedical Sciences, New York, NY | Memorial Sloan Kettering Cancer Center, New York, NY | Herbert Irving Comprehensive Cancer Ctr., New York, NY | Chief, Division of Pediatric Hematology/, Memorial Sloan Kettering Cancer Center, New York, NY	Spatial transcriptomic profiling reveals heterogeneity in desmoplastic small round cell tumor 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4965	Wafaa Bzeih, Yan Tang, Tiegang Han, Andrew J. Sedgewick, Nathan D. Maulding, Carmen Priolo, Katrina Collins, Hadi Mansour, Joelle Chami, Michelle M. Stein, Justin Guinney, Michel Alchoueiry, Jessica F. Williams, Michelle S. Hirsch, Pavlos Msaouel, Elizabeth P. Henske	Department of Medicine, Harvard Medical School/Brigham and Women's Hospital, Boston, MA | Tempus AI, Inc., Chigaco, IL | Indiana University School of Medicine, Indianapolis, IN | Department of Pathology, Harvard Medical School / Brigham and Women's Hospital, Boston, MA | Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX	Sarcomatoid transformation rewires the immune spatial landscape and checkpoint regulation in chromophobe renal cell carcinoma 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4986	Sowon Choi, Hee Jin Lee, Byung-Kwan Jeong, Hyun Je Kim	Seoul National University, Seoul, Korea, Republic of | Asan Medical Center, Seoul, Korea, Republic of	Identification of tumor microenvironment for high infiltration of lymphocytes in triple negative breast cancer 4/21/2026 9:00:00 AM | Tumor-Immune Crosstalk Open abstract	Xenium
5496	Mariia Bilous, Daria Buszta, Jonathan Bac, Senbai Kang, Yixing Dong, Stephanie Renaud-Tissot, Sylvie Andre, Marina Alexandre-Gaveta, Christel Voize, Solange Peters, Krisztian Homicsko, Raphael Gottardo	Biomedical Data Science Center, Lausanne University Hospital; University of Lausanne, Lausanne, Switzerland | Department of Oncology, Lausanne University Hospital; Swiss Cancer Center Leman, Lausanne, Switzerland	From transcripts to cells: Dissecting sensitivity, signal contamination, and specificity in Xenium spatial transcriptomics 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium
6118	Junghan Oh, Hoyeon Jeong, Yoon La Choi, Donggun Lee, Misook Lee	Samsung Advanced Institute of Technology, Seoul, Korea, Republic of | Samsung Advanced Institute for Health Sciences and Technology, Seoul, Korea, Republic of	Spatially resolved SEED (stromal-enriched metastatic decider) niches integrate tumor, stromal, and immune ecosystems to enable lymph node dissemination in LUAD 4/21/2026 2:00:00 PM | Metastasis and Organ-Specific Microenvironmental Evolution Open abstract	Xenium
6194	Harim Chun, Yeoun Eun Sung, Sook Hee Hong, Sangjeong Ahn, Sung Hak Lee	Department of Medical Science, Graduate School, The Catholic University of Korea, Seoul, Korea, Republic of | Department of Hospital Pathology, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea, Republic of | Division of Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of | Department of Pathology, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, Korea, Republic of	Spatial architecture of immunochemotherapy response in pleural mesothelioma 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium
6478	KyuTae Hwang, Seowoo Kim, Mi Zhou, William Y. Kim, Minyong Kang	Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology (SAIHST), Seoul, Korea, Republic of | UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC | UNC Chapel Hill, Cary, NC | Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology (SAIHST)Samsung Medical Center, Seoul, Korea, Republic of	Temporal dynamics of T cell reprogramming associate with clinical response to ICI-based combination therapy in metastatic renal cell carcinoma 4/21/2026 2:00:00 PM | Clinical Correlates of Immunotherapy Open abstract	Xenium
6663	Qanber Raza, Nick Zabinyakov, Lauren Tracey, Liang Lim, Christina Loh	Standard BioTools, Markham, ON, Canada	Integrated spatial transcriptomic and proteomic profiling reveals tumor-immune niches driving heterogeneity and resistance in clear cell renal cell carcinoma 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	Xenium
6741	M. Li, X. Hoi, J. Deng, J. Zheng, R. Hashmani, R. Bayraktar, W. Qian, J. Zhou, J. Guan, K. Sun, H. Mai, T. Sheu, S. Haley, M. Schwartz, S. Mathur, S. T. Wong, F. Nikolo, K. Chan, P. Niravath, J. C. Chang; Houston Methodist Research Institute, Houston, TX, Houston Methodist Hospital, Houston, TX		Tertiary lymphoid structure (TLS)-associated immune circuits define response to durvalumab, trastuzumab, and pertuzumab (DTP) in HER2-enriched early breast cancer 4/21/2026 2:50:00 PM | Immunotherapy: Mechanisms and Responses Open abstract	Xenium
6788	B. Zhu, M. Aminu, Y. Tian, S.-W. Lu, O. Shi, W. Lu, H. Chen, H. Li, Z. Wei, M. B. Nilsson, L. Solis Soto, F. P. Andrew, D. L. Gibbons, J. V. Heymach, C. Cheng, J. Wu, J. Zhang; UT MD Anderson Cancer Center, Houston, TX, The University of Texas MD Anderson Cancer Center, Baylor College of Medicine, Houston, TX		Spatial single-cell analysis reveals stage-dependent mechanisms of anti-IL-1β therapy in lung adenocarcinoma 4/21/2026 3:20:00 PM | Inflammation and Immunity in Cancer Progression Open abstract	Xenium; Visium
6895	Yufeng He, Yanping Zhao, Rui Zhang, Heli Yang, Zhaode Bu, Yuan Luo, Deng Pan, Zexian Zeng	Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China | Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China | Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Peking University, Beijing, China | Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL | Tsinghua-Peking Center for Life Sciences, Department of Basic Medical Sciences, Tsinghua University, Beijing, China	DISSECT integrates cytological images and spatial transcriptomics for cell segmentation 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	Xenium; Visium; CosMx
LB199	Praveen Bhoopathi, Khoa L. A. Huynh, Erica J. Peterson, Vashti Bandy, Anna Gibson, Vignesh Vudatha, Arunima Punjala, Dongyu Zhang, Jinze Liu, J Chuck Harrell, Nicholas P. Farrell, Jose G. Trevino	Dept of Surgery, Massey Comprehensive Cancer Center, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Biostatistics, Massey Comprehensive Cancer Center, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Internal Medicine, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Surgery, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Pathalogy, Massey Comprehensive Cancer Center, Virginia Commonwealth University - VCU, Richmond, VA | Dept of Chemistry, Virginia Commonwealth University- VCU, Richmond, VA	High-plex spatial transcriptomics reveals triplatin-induced DNA damage signaling and tumor-fibroblast niche reprogramming in pancreatic cancer PDX models 4/20/2026 2:00:00 PM | Late-Breaking Research: Experimental and Molecular Therapeutics 2 Open abstract	Xenium
LB237	Wei Zhao, Aaron Rozeboom, Phuc H. Hoang, Tam-Anh Tran, Maria Teresa Landi	National Cancer Inst. Div. of Cancer Epidemiology & Genetics, Bethesda, MD | Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD	High-resolution spatial transcriptomics identifies unique spatial programs in lung adenocarcinoma from never smokers 4/20/2026 2:00:00 PM | Late-Breaking Research: Tumor Biology 1 Open abstract	Xenium; Visium

Abstract #	Authors	Affiliation	Title / Session	Products
12	Francisco G. Carranza, Brigette Waldrup, Yuxin Jin, Yonatan Amzaleg, David Craig, John Carpten, PE-CGS Network, Enrique I. Velazquez Villarreal	Department of Integrative Translational Sciences, City of Hope National Medical Center, Duarte, CA	Integrative spatial multi-omics profiling enhanced by artificial intelligence reveals ancestry-associated molecular features in early-onset colorectal cancer among Southern California patients 4/19/2026 2:00:00 PM | AACR Project GENIE: Predictive Models and AI Open abstract	Visium
77	Cristina Almagro-Pérez, Andrew Song, Luca Weishaupt, Ahrong Kim, Guillaume Jaume, Konstantin Hemker, Drew F.K. Williamson, Stephanie Pei Tung Yiu, Qinghua Han, Renao Yan, Elena Baraznenok, Long Phi Le, Alexander S. Baras, Ali Bashashati, Sizun Jiang, Jonathan T.C. Liu, Faisal Mahmood	Brigham and Women's Hospital, Boston, MA | Pusan National University, Busan, Korea, Republic of | Emory University, Atlanta, GA | Harvard Medical School, Boston, MA | Stanford University, Palo Alto, CA | Johns Hopkins Medicine, Baltimore, MD | University of British Columbia, Vancouver, BC, Canada	AI-driven 3D spatial transcriptomics for 3D tumor microenvironment mapping in prostate adenocarcinoma 4/19/2026 2:00:00 PM | Digital Pathology 1 Open abstract	Visium
94	Erin L. Brown, Wubing Zhang, Abul Usmani, Noah Earland, Ayesha Hashmi, Chibuzor Olelewe, Anushka Viswanathan, Pradeep S. Chauhan, Minji Kang, Chloé B. Steen, Hyun Soo Jeon, Susanna Avagyan, Irfan Alahi, Nicholas P. Semenkovich, Matteo Bergsagel, Janella C. Schwab, Chloe M. Sachs, Kaushal Parikh, Faridi Qaium, Peter K. Harris, Antonella Bacchiocchi, Qingyuan Cai, Andrew J. Gentles, Rondell P. Graham, Peter C. Lucas, Ryan C. Fields, Jacob J. Orme, Aaron S. Mansfield, Mario Sznol, Ruth Halaban, David Y. Chen, Aaron M. Newman, Aadel A. Chaudhuri	Stanford University School of Medicine, Stanford, CA | Washington University in St. Louis, St. Louis, MO | Mayo Clinic, Rochester, MN | Oslo University Hospital and University of Oslo, Oslo, Norway | Medical College of Wisconsin, Milwaukee, WI | Yale University School of Medicine, New Haven, CT | Columbia University, New York, NY | University of Rochester School of Medicine, Rochester, NY	Liquid biopsy profiling of the tumor microenvironment to determine response to immunotherapy regimens across solid tumors 4/19/2026 2:00:00 PM | Liquid Biopsy: Multi-Analyte and Multi-Omic Open abstract	Visium
636	Torsten Pietsch, Verena Dreschmann, Pia Zapka, Evelyn Dörner, Christian Vokuhl	Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany | Department of Pathology, University of Bonn Medical Center, Bonn, Germany	Dissecting the complex ecosystem of intracranial germ cell tumors by spatial RNA and protein analysis 4/19/2026 2:00:00 PM | Developmental Origins, Drivers, and Heterogeneity in Pediatric Cancer Open abstract	Visium
639	Joseph Seamus Toker, Katherine Elizabeth Masih, Noemi Kedei, Zahin Islam, Ben J. Somerville, Amir Jassim, Michail Mamalakis, Aysen Yuksel, Daniel R. Catchpoole, Li Zhou, Paul Aiyetan, Yong Yean Kim, David Milewski, Shaoli Das, Xinyu Wen, Yong Song, Jun Wei, Richard J. Gilbertson, Javed Khan	University of Cambridge, Cambridge, United Kingdom | National Cancer Institute, Bethesda, MD | Tumour Bank, Children's Cancer Research Unit, The Children's Hospital at Westmead, Westmead, NSW, Australia | Neopathology Corp, Frederick, MD | Pediatrics, Stanford University, Stanford, CA	Distinct microenvironments define subtypes of neuroblastoma 4/19/2026 2:00:00 PM | Developmental Origins, Drivers, and Heterogeneity in Pediatric Cancer Open abstract	Visium
711	Asumi Iesato, Masashi Akiya, Kazutaka Otsuji, Sumito Saeki, Natsue Uehiro, Tetsuo Noda, Tomo Osako, Takayuki Ueno, Reo Maruyama	Japanese Foundation for Cancer Research, Tokyo, Japan	Single-cell and spatial profiling identifies tumor features and actionable surface targets in primary breast angiosarcoma 4/19/2026 2:00:00 PM | Molecular Pathology Open abstract	Visium
1037	Mehdi Lamkhioued, Thimothee Casini, Elodie Girard, Karène Mahtouk, Sonia Canjura-Rodriguez, Valery Attignon, Bastien Cabarrou, Constance Lamy, Anne Schnitzler, Frederique Penault-Llorca, Caroline Even, Christophe Le Tourneau, Ellen Van Obberghen-Schilling, Nicolas Servant, Fayette Jerome, Nathalie Bendriss-Vermare, Ivan Bièche, Pierre Saintigny	Ctr. Léon Bérard, Lyon, France | Inst. Curie, Paris, France | IUCT Oncopole, Toulouse, France | Gustave Roussy, Paris, France | Université côte d'Azur, Nice, France | Genetics Department, Inst. Curie, Paris, France	Single cell and spatially resolved determinants of the clinical outcome of patients (pts) treated with locally advanced/metastatic head and neck squamous cell carcinoma (LA/M SCCHN) treated with immunotherapy (IO) 4/19/2026 2:00:00 PM | Biomarkers Predictive of Therapeutic Benefit 2 Open abstract	Visium
1201	Yunhe Liu, Idania Carolina Lubo Julio, Wei Lu, Alejandra G. Serrano, Jean R. Clemenceau, Amber Famiglietti, Karen Colbert, Yibo Dai, Yang Liu, Jun Wang, Jeremy L. Davis, Mingyao Li, Paul F. Mansfield, Tae Hyun Hwang, Luisa M. Solis-Soto, Linghua Wang	Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Surgery, Vanderbilt University Medical Center, Nashville, TN | National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD | Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX | BioChemistry&Molecular Biology, University of Maryland School of Medicine, Baltimore, MD | University of Pennsylvania, Philadelphia, PA | Vice President, Acute Care Services, UT MD Anderson Cancer Ctr., Houston, TX | Department of Translational Molecular Pathology, the university of MD Anderson cancer center, Houston, TX	Spatial 3D and multi-omics mapping of diffuse gastric cancer evolution from preinvasive to invasive lesions in CDH1 mutation carriers 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium; CosMx; GeoMx; G4X
1205	Junyan Liu, Md Tauhidul Islam, Lei Xing	Stanford University, Palo Alto, CA	Trajectory-aware spatial transcriptomics deconvolution via image representation of RNA-seq data 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium
1207	Duaa Hassan Al-Rawi, Nataly Naser Al Deen, Cristina Sotomayor-Vivas, Kerstin Thol, Herman Chui, Aveline Filliol, Areej Alsaafin, Hunter Green, Danguole Norkunaite, Mercedes Duran, Nicholas Ceglia, Kara Long-Roche, Britta Weigelt, Andrew McPherson, Scott W. Lowe, Sohrab Shah	Memorial Sloan Kettering Cancer Center, New York, NY | Assistant Member (Level 1), Dept. of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY	Multimodal profiling of STIC lesions identifies precursor states with genomic features of high grade serous ovarian cancer 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1209	Diana Bell, Randal S. Weber, Miao Zhang, Michelle Afkhami, Raja R. Seethala	University of Pittsburgh, Pittsburgh, PA | University of Texas MD Anderson Cancer Center, Houston, TX | City of Hope, Duarte, CA	FGFR2 translocated sinonasal adenocarcinoma: A biphasic seromucinous adenocarcinoma with a distinctive and targetable molecular phenotype 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1210	Kazutaka Otsuji, Tomo Osako, Yoko Takahashi, Chikako Shibata, Sumito Saeki, Asumi Iesato, Tetsuo Noda, Kengo Takeuchi, Takayuki Ueno, Reo Maruyama	NEXT-Ganken Program, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Division of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Breast Oncology Center, Cancer Institute Hospital of JFCR, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Division of Cancer Epigenomics, Cancer Institute, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Director's room, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan	Integrated spatial and single-cell profiling uncovers a pre-existing, treatment-resistant subclone that drives early local relapse in luminal breast cancer 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium
1211	Changhee Park, Minki Choi, Jiwon Koh, Sungwoo Bae, Hongyoon Choi, Kwon Joong Na, Dae-Won Lee, Kyung-Hun Lee, Han Suk Ryu, Seock-Ah Im	Seoul National University Hospital, Seoul, Korea, Republic of | Pathology, Asan Medical Center, Seoul, Korea, Republic of | Pathology, Seoul National University Hospital, Seoul, Korea, Republic of | Portrai Inc., Seoul, Korea, Republic of	Spatial transcriptomics uncovers pharmacokinetic barriers and tumor-intrinsic determinants of resistance to trastuzumab deruxtecan in breast cancer 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1212	Whitney Tamaki, Daniel L. Kerr, Wei Wu, Grant Eilers, Anatoly Urisman, Yu-Ting Chou, Philippe Gui, Shigeki Nanjo, Johannes Ruediger Kratz, David Jablons, Trever G. Bivona, Collin M. Blakely	UCSF, San Francisco, CA | University of Washington, Seattle, WA | Anatomic Pathology, UCSF, San Francisco, CA | Kanazawa Univ. Hospital, Kanazawa, Japan | Clinical Fellow, Medical Oncology, UCSF, San Francisco, CA	Spatial transcriptomics reveals distinct SPP1-CD44 signaling networks in neoadjuvant osimertinib treated EGFR mutant non-small cell lung cancer 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1215	Prachi Bhave, Marie Trussart, Anthony T. Papenfuss, Grant A. McArthur	The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia | Walter & Eliza Hall Institute of Medical Research, Melbourne, Australia | Peter MacCallum Cancer Centre, Melbourne, Australia	Spatial transcriptomic analysis of primary melanomas with extreme clinical outcomes 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1216	Antoine Cazelles, Camilla Pilati, Delphine Le Corre, Gadea Cabrejas, Marine Sroussi, Claire Mulot, Claire Gallois, Gilles Manceau, Mehdi Karoui, Isaias Hernández-Verdin, Antoine Bougoüin, Wolf-Herman Fridman, Aurélien de Reyniès, Côme Lepage, Thierry Andre, Jean-François Emile, Théo Z. Hirsch, Julien Taieb, Pierre Laurent-Puig, Sophie Mouillet-Richard	Centre de Recherche des Cordeliers, Paris, France | University of Burgundy and Franche Comté, Dijon, France | Hôpital Saint-Antoine, Paris, France | Ambroise-Paré Hospital, Boulogne, France	Profiling colon cancer architecture with spatial transcriptomics identifies clinically relevant stromal ecotypes 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1217	Gopikrishnan Bijukumar, Kathryn J. Brayer, David Lee, Scott A. Ness, Jeremy S. Edwards, Viswanathan Palanisamy	Chemistry and Chemical Biology / Cancer Research Facility, University of New Mexico, Albuquerque, NM | University of New Mexico, Albuquerque, NM | Professor, Dept. of Molec. Genetics & Microbiol., University of New Mexico School of Medicine - Albuquerque, Albuquerque, NM | Internal Medicine / Comprehensive Cancer Center, University of New Mexico Health Sciences, Albuquerque, NM	Multi-omics integration of bulk, single-cell, and spatial transcriptomics identifies robust prognostic biomarkers in head and neck salivary adenoid cystic carcinoma 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1416	Sabrina Akter, Aiman Soliman, Robert A. Winn, Zeynep Madak-Erdogan, Sage J. Kim	Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Champaign, IL | National Center for Supercomputing Applications, University of Illinois Urbana-Champaign, Champaign, IL | VCU Massey Comprehensive Cancer Center, Richmond, VA | School of Public Health, University of Illinois Chicago, Chicago, IL	Stress-responsive glucocorticoid receptor signaling shapes the immune tumor microenvironment in lung cancer 4/20/2026 9:00:00 AM | Application of Bioinformatics to Cancer Biology 2 Open abstract	Visium
1419	Bohyeon Yu, Emanuele Filiberto Rosatti, Jangham Jung, Abhinav Jain, Joanna Phillips, Aaron Antonio Diaz	Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA | Department of Cellular, Computational and Integrative Biology, University of Trento, Trentino, Italy	Integrated spatial and genetic lineage tracing uncovers cell state plasticity underlying recurrence in group3 and group4 medulloblastoma 4/20/2026 9:00:00 AM | Application of Bioinformatics to Cancer Biology 2 Open abstract	Xenium; Visium
1442	Minh-Khang Le, Vivek Pujara, I-Chuang Liao, Yuan Yuan, Joseph Lownik, Graeme Murray, Jin Sun Bitar, Luxi Chen, Parisa Najafzadeh, Keeyon Dabirian, David Lin, Fred W Kolling IV, Parth S. Shah, Jonathan Marotti, Xiaoying Liu, Louis J. Vaickus, Keluo Yao, Linda T. Vahdat, Zarif L. Azher, Joshua Levy	Cedars-Sinai Medical Center, Los Angeles, CA | Huntington Health, Pasadena, CA | Dartmouth Geisel School of Medicine, Hanover, NH | Dartmouth Hitchcock Medical Center, Lebanon, NH | Zarif Azher (Individual), Great Falls, VA	Spatial transcriptomics informed tumor purity estimation from histology slides for triple negative breast cancer 4/20/2026 9:00:00 AM | Digital Pathology 2 Open abstract	Visium
1476	Steven Yan, Limin Jiang, Yan Guo	University of Miami Miller School of Medicine, Miami, FL | University of Miami, Miami, FL	Improve spatial transcriptomic data with integrated hybrid transformer and graph convolutional networks 4/20/2026 9:00:00 AM | Integrative Computational Approaches 1 Open abstract	Xenium; Visium; CosMx
1487	Raymond Yan, Brian Falkenstein, A. Burak Tosun, Filippo Pullara, S. Chakra Chennubhotla	PredxBio, Inc., Pittsburgh, PA | PredxBio, Inc. / University of Pittsburgh, Pittsburgh, PA	Spatial microdomains from histology reveal multi-omic biomarkers for enhanced idiopathic pulmonary fibrosis diagnosis 4/20/2026 9:00:00 AM | Integrative Computational Approaches 1 Open abstract	Xenium; Visium
2093	Jonathan Castillo, William D. Wallace, Leonidas Arvanitis, Dan Raz, Crystal N. Marconett	Department of Integrative Translational Sciences, City of Hope, Duarte, CA | Department of Pathology, USC Keck School of Medicine, Los Angles, CA | Department of Pathology, City of Hope, Duarte, CA | Division of Thoracic Surgery, Department of Surgery, City of Hope, Duarte, CA	Elucidating the mechanistic connection between the elevated occurrence of EGFR mutation in Hispanic/Latinx lung adenocarcinoma patients 4/20/2026 9:00:00 AM | Aging and Host Determinants of Tumor Progression: The Macroenvironmental Axis Open abstract	Visium
2123	Haley du Bois, Alberto Chaves, Mostafa Nasr, Tao Li, Karl Nyman, Ryan Bishop, Conor C. Lynch	Tumor Microenvironment & Metastasis, Moffitt Cancer Center, Tampa, FL | University of South Florida, Tampa, FL | Moffitt Cancer Center, Tampa, FL	A high resolution spatial transcriptomic atlas of the bone marrow microenvironment pre and post prostate cancer seeding 4/20/2026 9:00:00 AM | Characterization of Metastases by Imaging and Profiling Open abstract	Visium
2253	Fushun Chen, Lorena Isabel Gomez, Tieling Zhou, Yuejiang Liu, Inti C. Tarifa Reischle, Sujuan Yang, Manvi Sharma, ,Jiping Feng, Jaafar Hadi, Fuduan Peng, Yibo Dai, Mhenaz Hossain, Ratna Veeramachaneni, Ansam Sinjab, Sean Anderson, Dhrishit Mangrolia, Deborah Rodriguez, Nadim Ajami, Jennifer Wargo, Adel El-Naggar, Roberto Rangel, Nadarajah Vigneswaran, Linghua Wang, Jeffrey N. Myers, Humam Kadara	UT MD Anderson Cancer Center, Houston, TX | UT Health School of Dentistry, Houston, TX	Multimodal and multikingdom spatial transcriptomics identify bacterial niches implicated in oral cancer development 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2255	Yibo Dai, Fuduan Peng, Ansam Sinjab, Yunhe Liu, Sujuan Yang, Lorena I Gomez Bolanos, Tieling Zhou, Minyue Chen, Alejandra G Serrano, Jianlong Liao, Guangsheng Pei, Yang Liu, Jiahui Jiang, Kyung Serk Cho, Kai Yu, Jiping Feng, Zahraa Rahal, Naoe Jimbo, Takuo Hayashi, Satsuki Kishikawa, Kazuya Takamochi, Avrum Spira, Steven M. Dubinett, Tomoo Itoh, Takashi Yao, Kenji Suzuki, Stephen G. Swisher, Mingyao Li, Junya Fujimoto, Ignacio Wistuba, Jared K. Burks, Kadir Caner Akdemir, Hind Rafei, Katayoun Rezvani, Jeffrey N. Myers, Humam Kadara, Linghua Wang	UT MD Anderson Cancer Center, Houston, TX | Kobe University Hospital, Kobe, Japan | Juntendo University Graduate School of Medicine, Tokyo, Japan | Lung Cancer Initiative at Johnson and Johnson, Boston, MA | UCLA David Geffen School of Medicine, Los Angeles, CA | University of Pennsylvania, Philadelphia, PA | Hiroshima University Hospital, Hiroshima, Japan | Moffitt Cancer Center & Research Institute, Tampa, FL	Spatial transcriptomics reveals evolving tumor microenvironmental archetype along the lung premalignancy-adenocarcinoma continuum 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2259	Siyuan He, Aatish Thennavan, Runmin Wei, Shanshan Bai, Jianzhuo Li, Chante Bethell, Emi Sei, Mitchell Rao, Tapsi Kumar, Chenling Tang, Ivan Marin, Jessica Montalvan, Chandandeep Nagi, Bora Lim, Savitri Krishnamurthy, Alastair Thompson, Nicholas E. Navin	UT MD Anderson Cancer Center, Houston, TX | Baylor College of Medicine, Houston, TX | Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, TX	Reprogramming of the stromal and immune microenvironment in preinvasive breast cancer 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2264	Kwon Joong Na, Hongyoon Choi, Jaemoon Koh, Taeyoung Yun, Jihyeon Park, Bubse Na, Samina Park, In Kyu Park, Chang Hyun Kang, Young Tae Kim	Seoul National University Hospital, Seoul, Korea, Republic of	Spatial trajectories and niche rewiring from ground‑glass to solid transition in lung adenocarcinoma 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Visium
2272	Akifumi Mochizuki, Ayako Suzuki, Kouya Shiraishi, Masahiro Torasawa, Takayuki Honda, Susumu Kirimura, Yasunari Miyazaki, Kenichi Okubo, Syuzo Kaneko, Yukihiro Yoshida, Shun-ichi Watanabe, Masahiro Tsuboi, Genichiro Ishii, Issei Imoto, Ryuji Hamamoto, Yasushi Yatabe, Yutaka Suzuki, Takashi Kohno	Department of Respiratory Medicine, Institute of Science Tokyo, Tokyo, Japan | Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan | National Cancer Center Research Institute, Tokyo, Japan | Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan | Division of Pathology, Institute of Science Tokyo, Tokyo, Japan | Department of Thoracic Surgery, Institute of Science Tokyo, Tokyo, Japan | Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan | Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan | Department of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan | Department of Pathology and Clinical laboratories, National Cancer Center Hospital East, Kashiwa, Japan | Dept. of Human Genetics, Inst. of Health Biosciences, Aichi Cancer Center Research Institute, Nagoya, Japan | Associate Professor, National Cancer Center Japan, Tokyo, Japan | Chief, Dept. of Pathology & Molec. Diagnostics, National Cancer Center, Nagoya, Japan	Dichotomous immunogenetic landscape of lung adenocarcinoma associated with usual interstitial pneumonia 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Xenium; Visium
2496	Harrshavasan Congivaram, Shashwat Tripathi, Mateo Gomez, Katy McCortney, Ching Man Wai, Ruochen Du, Thomas K. Sears, Daniel J. Brat, Craig M. Horbinski, Mark W. Youngblood, Jared T. Ahrendsen, Adam M. Sonabend, Stephen T. Magill, Matthew C. Tate, Maciej S. Lesniak, Sean Sachdev, Timothy Sita, Priya Kumthekar, Karan Dixit, Robin Buerki, Ditte Primdahl, Mustafa Khasraw, John de Groot, David A. Reardon, Rimas V. Lukas, Roger Stupp, Amy B. Heimberger	Neurological Surgery, Northwestern Univ. Feinberg School of Medicine, Chicago, IL | Biochemistry and Molecular Genetics, Northwestern Univ. Feinberg School of Medicine, Chicago, IL | Professor, Dept. of Path. & Lab Med., Northwestern University - Evanston, IL, Chicago, IL | Department of Laboratory Medicine and Pathology, Mayo Clinic Jacksonville, Chicago, IL | Pathology, Northwestern Univ. Feinberg School of Medicine, Chicago, IL | Radiation Oncology, Northwestern Univ. Feinberg School of Medicine, Chicago, IL | Neurology, Northwestern Univ. Feinberg School of Medicine, Chicago, IL | Duke Cancer Institute, Durham, NC | Neuro-Oncology, University of California San Francisco, San Franscisco, CA | Ctr. for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA	In silico screeening of therapeutics candidates targeting minimal residual disease in glioblastoma 4/20/2026 9:00:00 AM | Data-Driven Approaches to Precision Oncology Open abstract	Visium
2686	Kanae Echizen, Yoshiki Nonaka, Tomonori Kamiya, Maho Tsuda, Yoshimi Yukawa-Muto, Hideki Fujii, Kenichi Kohashi, Ryo Takahashi, Takahiro Kodama, Naoko Ohtani	Graduate School of Medicine, Department of Pathophysiology, Osaka Metropolitan University, Osaka, Japan | Graduate School of Medicine, Department of Hepatology, Osaka Metropolitan University, Osaka, Japan | Graduate School of Medicine, Department of Pathology, Osaka Metropolitan University, Osaka, Japan | Graduate School of Medicine, Department of Gastroenterology and Hepatology, Osaka University, Suita, Japan	Extraction of cellular networks and microenvironmental characteristics in liver cancer tissues using geospatial approaches for therapeutic and diagnostic potential 4/20/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 3 Open abstract	Visium
2700	Orian Stapleton, Dmitrijs Lvovs, Luciane Tsukamoto Kagohara, Elana Judith Fertig, Atul Deshpande	Johns Hopkins University, Baltimore, MD | University of Maryland School of Medicine, Baltimore, MD	SpaceMarkers 2.0: A framework for spatially aware cell-cell communication in spatial transcriptomic data 4/20/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 3 Open abstract	Visium
2754	Haenara Shin, Dongjoo Lee, Jeongbin Park, Hongyoon Choi	Portrai, Inc., Seoul, Korea, Republic of	VGL: Vision-Gene-Language multimodal LLM integrating histopathology and gene expression for cell type classification in lung cancer 4/20/2026 2:00:00 PM | Large Language Models in the Clinic Open abstract	Xenium; Visium
3000	Julius Beichert, Jonas A. Kretz, Jena Kim, Xiaoyu Ma, Daniel Dominguez Azorín, Andreas E. Moor, Haikun Liu, Miriam Ratliff	Department of Neurosurgery, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg and German Cancer Research Center (DKFZ), Mannheim, Heidelberg, Germany | Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland | Molecular Neurogenetics, German Cancer Research Center (DKFZ), Heidelberg, Germany	Tumor Treating Fields (TTFields) may weaken glioblastoma network connectivity, with implications for malignancy 4/20/2026 2:00:00 PM | Molecular Targets 1 Open abstract	Visium
3435	Heesoo Yoon, Jin-Wook Choi, Sejoon Lee, Jin-Haeng Chung, Hyojin Kim	Department of Pathology, Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of | Precision Medicine Center, Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of	Spatial transcriptomic profiling reveals distinct tumor microenvironment remodeling patterns associated with immune checkpoint blockade response in lung adenocarcinoma 4/20/2026 2:00:00 PM | Microenvironmental Determinants of Therapy Response and Resistance 1 Open abstract	Visium
3444	Wesley V. Wilson, MacLean P. Nasrallah, Nakial Cross, Yael A. Day, Vanessa Gonzalez, Rachel M. Leskowitz, Amy Marshall, Julie K. Jadlowsky, Gabriela Plesa, Donald L. Siegel, Elizabeth O. Hexner, Joseph A. Fraietta, Carl H. June, Stephen J. Bagley, Donald O’Rourke, Zev Binder, Andrew J. Rech	Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada | Penn Medicine, Philadelphia, PA | Perelman School of Medicine Univ. of Pennsylvania, Philadelphia, PA | CCI, Penn Medicine, Philadelphia, PA | University of Pennsylvania, Philadelphia, PA | Program Director of Translational Research, Abramson Family Cancer Research Inst, University of Pennsylvania, Philadelphia, PA	Spatial profiling of recurrent glioblastoma in a Phase I clinical trial reveals favorable immune remodeling induced by intracerebroventricular CAR T therapy 4/20/2026 2:00:00 PM | Microenvironmental Determinants of Therapy Response and Resistance 1 Open abstract	Visium; CosMx; GeoMx
3617	Foram Ujjvalkumar Vaidya, Alvaro Gutierrez, Abberly Lott Limbach, Bhavna Kumar, Martin P. Alphonse, James W. Rocco, Mariana Brait, Amanda Ewart Toland, David Sidransky	The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD | Centro de Excelencia en Medicina Traslacional, Universidad de La Frontera, Temuco, Chile | Department of Pathology, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH | Department of Otolaryngology-Head and Neck Surgery, OSU Comprehensive Cancer Center, The Ohio State University, Columbus, OH | Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD | Department of Cancer Biology and Genetics, OSU Comprehensive Cancer Center, The Ohio State University, Columbus, OH	Immunogenomic alterations driving premalignant lesions to invasive lesions of the head and neck 4/20/2026 2:00:00 PM | Metabolism and Microbiome in Cancer Initiation and Prevention Open abstract	Visium
3768	Chung Ji LIu, Hui-Wen Cheng, Li-Han Lin, Kuo-Wei Chang	Department of Oral and Maxillofacial Surgery, Mackay Memorial Hospital, Taipei, Taiwan | Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan | School of Denstry, National Yang Ming Chiao Tung University, Taipei, Taiwan	Spatially resolved lineage and microenvironmental remodeling define metastatic progression in oral squamous cell carcinoma 4/20/2026 2:00:00 PM | Circulating Tumor Cells, Metastasis, and Dissemination Biology 2 Open abstract	Visium
3957	Changjin Hong, Sunho Park, Jean R. Clemenceau, Minji Kim, Inyeop Jang, Seock-Jin Chung, Sung Hak Lee, Sam C. Wang, Tae Hyun Hwang	Section Surgical Research, Vanderbilt University Medical Center, Nashville, TN | St. Mary's Hospital Pathology, The Catholic University of Korea, Seoul, Korea, Republic of | Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX	Spatially derived transcriptomic predictors of immune checkpoint blockade outcome in advance gastric cancer 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	Visium
3961	Alyona Ivanova, Shamini Ayyadhury, Yanxia Ma, Xuehong Gui, Akshay V. Basi, Megan Yijun Wu, Trevor J. Pugh, David G. Munoz, Sungnam Cho, Tosin Oyewale, Lucas Schütz, Chibawanye I. Ene, Jared K. Burks, Sunit Das	University of Toronto, Toronto, ON, Canada | PMGC, UHN, Toronto, ON, Canada | MD Anderson, Houston, TX | Lab Research Project Coordinator, The Hospital for Sick Children, Toronto, ON, Canada | UHN Princess Margaret Cancer Centre, Toronto, ON, Canada | St. Michael's Hospital, Toronto, ON, Canada | Ariadne.ai, Heidelberg, Germany | Asst. Professor, Dept. of Surgery, University of Toronto, Toronto, ON, Canada	Identifying the molecular signature of infiltrating edge cells in glioblastoma as drivers of tumour invasion and recurrence 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	Visium
3975	Yufeng He, Ce Luo, Yuanguang Meng, Zhe Zhang, Zexian Zeng	Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China | Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China | Department of Obstetrics and Gynecology, Seventh Medical Center of Chinese PLA General Hospital, Beijing, China	Spatially resolved multi-omics reveal metastatic ecosystem remodeling and immunomodulatory niches in HGSOC 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	Visium
4021	Y.-C. Kao, S. X. Tan, X. Tan, H. Oey, K. J. Lee, T. Vallius, R. Pelletier, A. Causer, C. Zhou, D. Smit, J. O'Neill, A. Xiong, B. O'Brien, A. Collins, P. K. Sorger, H. Soyer, K. Khosrotehrani, Q. Nguyen, M. S. Stark; Frazer Institute, The University of Queensland, Dermatology Research Centre, Brisbane, Australia, QIMR Berghofer Medical Research Institute, Brisbane, Australia, Harvard Medical School, Brookline, MA, Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, Institute for Molecular Bioscience, the University of Queensland, Brisbane, Australia, QIMR Medical Research Institute, Queensland, Australia, Brisbane, Australia, Sullivan Nicolaides Pathology, Brisbane, Australia, Harvard Medical School, Winchester, MA		Precision diagnostics for early melanoma detection using spatial biology and AI guided image analysis 4/20/2026 4:05:00 PM | Biomarkers That Change Management: Predicting Therapy Benefit, Progression, and Metastatic Risk Open abstract	Xenium; Visium
4036	J. Luo, S. P. Gao, J. E. Tallman, F. Kuo, M. Basar, C. Yol, S. M. Alam, H. Jiang, X. Tang, D. X. T. Zheng, J. E. Eichholz, A. Lopez Rojas, E. Turkay, J. E. Rosenberg, G. Iyer, E. J. Pietzak, D. B. Solit, H. Al-Ahmadie; Memorial Sloan Kettering Cancer Center, New York, NY		Deciphering regulatory drivers of lineage plasticity and resistance to antibody-drug conjugates in urothelial bladder cancer 4/20/2026 3:20:00 PM | Cracking Adaptive Resistance: AI-Enabled, Screen-Guided Targets in Tumor Plasticity, DNA Damage, Metabolism, and CTC-Associated Immunity Open abstract	Visium
4124	Zixuan Lan, Philip Awadalla	Molecular Genetics, University of Toronto, Toronto, ON, Canada | Molecular Genetics, University of Oxford, Oxford, United Kingdom	Cancer stem cells and where to find them: Their trajectories and implications in cancer evolution 4/21/2026 9:00:00 AM | Application of Bioinformatics to Cancer Biology 4 Open abstract	Visium
4189	Thanosan Prathifkumar, Nehan Mohamed, Anvith Kakkera, Zarif Azher, Xiaoying Liu, Fred Kolling, Laurent Perreard, Scott Palisoul, Louis J. Vaickus, Joshua Jay Levy	Central Peel Secondary School, Brampton, ON, Canada | Thomas Jefferson High School for Science and Technology, Alexandria, VA | Dartmouth College Geisel School of Medicine, Hanover, NH | California Institute of Technology, Pasadena, CA | Dartmouth-Hitchcock Medical Center, Lebanon, NH | Cedars-Sinai Medical Center, Los Angeles, CA	Quantifying uncertainty in virtual spatial transcriptomics using Bayesian neural networks 4/21/2026 9:00:00 AM | Integrative Computational Approaches 2 Open abstract	Visium
4244	Maryam Al-Ghezi, Malia Rettig, Christopher P. Loo, Rashi Yadav, Wesley Yu, Joshua M. Moreau	Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR | Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR | Department of Dermatology, Oregon Health & Science University, Portland, OR	Investigating the spatial immune tumor microenvironment of dermatofibrosarcoma protuberans 4/21/2026 9:00:00 AM | Adaptive Immunity in Cancer Open abstract	Visium
4788	Ryuta Watanabe, Keito Kagimoto, Mami Chosei, Tomohisa Sakaue, Mie Kurata, Noriyoshi Miura, Riko Kitazawa, Tadahiko Kikugawa, Shigeki Higashiyama, Takashi Saika	Department of Urology, Ehime University Graduate School of Medicine, Toon, Japan | Department of Biochemistry and Molecular Genetics, Ehime University Graduate School of Medicine, Toon, Japan | Department of Cardiovascular and Thoracic Surgery, Ehime University Graduate School of Medicine, Toon, Japan | Department of Analytical Pathology, Ehime University Graduate School of Medicine, Toon, Japan | Division of Diagnostic Pathology, Ehime University Hospital, Toon, Japan | Department of Oncogenesis and Growth Regulation, Osaka International Cancer Institute, Osaka, Japan	PSMA-expressing tumor vasculature in renal cell carcinoma: spatial, functional, and therapeutic implications 4/21/2026 9:00:00 AM | Angiogenesis Open abstract	Visium
4903	Yuting Shan, Lilin Wang, Matthew Jeon, R. Stephanie Huang	University of Minnesota, College of Pharmacy, Minneapolis, MN | Asst. Professor, Dept. of Medicine, University of Minnesota, Minneapolis, MN	Explore the effects of Fusobacterium nucleatum on chemotherapy response in colorectal cancer at spatial and single-cell resolution 4/21/2026 9:00:00 AM | Microbiome-Tumor-Immune Crosstalk Open abstract	Visium
4945	Ji Hye Choi, Yeong Hak Bang, Kyung Yeon Han, Woong-Yang Park	Sungkyunkwan University, Seoul, Korea, Republic of | University of Ulsan College of Medicine, Seoul | Translational Genomics Center, Seoul, Korea, Republic of | GENINUS, Seoul, Korea, Republic of	Distinct colorectal cancer tumor cell subtypes revealed by single-cell and spatial transcriptomics 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium; Visium
4947	Xueshuai Han, Kohei Yamashita, Melissa Pool Pizzi, Kyung Serk Cho, Enyu Dai, Kai Yu, Yunhe Liu, Yibo Dai, Tian Chu, Matheus Sewastjanow-Silva, Hiro Yoshimura, Yibo Fan, Rebecca Waters, Qiong Gan, Feng Yin, Shilpa S. Dhar, Isadora Martins, Jason Willis, Mariela B. Murphy, Jenny Li, Brian D. Badgwell, Van K. Morris, Michael J. Overman, Linghua Wang, Jaffer A. Ajani	UT MD Anderson Cancer Center, Houston, TX | Gastrointestinal Medical Oncology, UT MD Anderson Cancer Center, Houston, TX	Spatially organized transcriptional programs and tumor-stroma interfaces shape immunotherapy response in microsatellite instability-high gastrointestinal cancers 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Visium
4949	Jiayi Zhou, Gabriel Cruz, Somnath Mahapatra, Radha Paturu, Hanbyul Cho, Xuhong Cao, Fengyun Su, Rui Wang, Dan Robinson, Yi-Mi Wu, Rohit Mehra, Kayla Muschong, Christine Caldwell Smith, Chelsea Decker, Chandan Kumar-Sinha, Saravana Mohan Dhanasekaran, Rahul Mannan, Yuping Zhang, Arul Chinnaiyan	University of Michigan, Ann Arbor, MI	High resolution spatial transcriptomics reveals dynamic remodeling of the tumor microenvironment during prostate cancer progression 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Visium
4952	Seo Hye Park, Jeongbin Park, Hongyoon Choi, Jaemoon Koh, Taeyoung Yun, Jihyeon Park, Bubse Na, Samina Park, In Kyu Park, Chang Hyun Kang, Young Tae Kim, Kwon Joong Na	Portrai, Inc., Seoul, Korea, Republic of | Department of Pathology, Seoul National University Hospital, Seoul, Korea, Republic of | Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Korea, Republic of	Spatial Transcriptomics reveals core resistance niches distinguishing non-MPR from MPR in NSCLC after neoadjuvant chemoimmunotherapy 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Visium
4954	Jerry A. Ombor, Anurendra Kumar, Jatin Gandhi, Rakesh Shiradkar, Tilak Pathak, Cynthia L. Winham, Ismaheel O. Lawal, Olayinka A. Abiodun-Ojo, Lara Harik, Saurabh Sinha, Martin G. Sanda, David M. Schuster, Adeboye O. Osunkoya, Carlos S. Moreno	Emory University, Atlanta, GA | Georgia Institute of Technology, Atlanta, GA | Indiana University, Indianapolis, IN	Integrated scRNAseq andspatial RNAseq analysis of aggressive prostatic adenocarcinoma identifies TIGIT-NECTIN 2/3 and TIGIT/PVRimmunosuppressive interactions 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Visium
4960	Bryan Bell, Cedric Uytingco, Alec Barrett, Bryant Ngo, Jonathan Sakkos, Diksha Kool, Wanxin Wang, Melissa del Rosario, Christina Chang, Christina Fan, Andrew Farmer	Takara Bio USA, San Jose, CA	Cross-platform comparison of spatial transcriptomics technologies in an FFPE lung squamous cell carcinoma sample 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium; Visium
4962	Fan Wei, Joy C. Yang, Kenneth Iczkowski, Marc A. Dall'Era, Chengfei Liu	Department of Urologic Surgery, University of California Davis, Sacramento, CA | Department of Pathology and Laboratory Medicine, University of California Davis, Sacramento, CA	Spatial transcriptomics reveals distinct ASCL1 and ASCL2 gene expression patterns in advanced prostate cancer 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Visium
5436	Tzu-Hung Hsiao, Fan Jhen Liu, Yu-Ting Kang, Kuo Yen Huang, Yidong Chen	Department of Medical Research, Taichung Veterans General Hospital, Taichung City, Taiwan | Graduate School of Advanced Technology, National Taiwan University, Taipei City, Taiwan | Greehey Children's Cancer Research Institute, UT Health San Antonio, San Antonio, TX	Spatial identification of hypoxic and normoxic dormancy hotspots predicting in her2-positive and metastatic breast cancer 4/21/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 5 Open abstract	Visium
5450	Sungwoo Bae, Jeongbin Park, Jin Yeong Choi, Daeseung Lee, Hyung-Jun Im, Hongyoon Choi	Portrai, Inc., Seoul, Korea, Republic of	Decoding ADC payload dynamics with a spatial transcriptomics-integrated tumor microenvironment PK model 4/21/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 5 Open abstract	Visium
5505	Yunhe Liu, Edoardo L. Draetta, Kayla R. Caughlin, Alexandria Lau, Andre Fonseca, Tian Chu, Kyung Serk Cho, Yibo Dai, Yang Liu, Jun Wang, Jiahui Jiang, Yinyin Yuan, Futreal Andrew, Mingyao Li, Linghua Wang	Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Translational Molecular Pathology,, The University of Texas MD Anderson Cancer Center, Houston, TX | Instituto Metropole Digital (IMD), Universidade Federal do Rio Grande do Norte (UFRN), Natal, Brazil | The University of Texas MD Anderson Cancer Center, Houston, TX | University of Pennsylvania, Philadelphia, PA	A unified framework for cross-platform spatial omics analysis and deep spatial profiling 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Visium
5514	Jingyi Wang, Hongpan Zhang, Zhenjia Wang, Chongzhi Zang	Department of Genome Sciences, University of Virginia, Charlottesville, VA | Department of Genome Sciences, University of Virginia, CHARLOTTESVILLE, VA	BART-spatial: Predicting biologically significant transcriptional regulators from spatial omics data 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Visium
5519	Junming Shi, Md Tauhidul Islam	Stanford University School of Medicine, Stanford, CA	SOMaC: An interpretable and generalizable framework for integrating and clustering multimodal spatial omics to resolve cell states and immune niches in cancer 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; Visium
5524	Mary Goldman, Brian Craft, Cally Lin, Jingchun Zhu, David Haussler	UC Santa Cruz Genomics Institute, Santa Cruz, CA | Stanford University, San Francisco, CA | Investigator/Distinguished Professor, Ctr. For Bio. Sci. & Eng., UC Santa Cruz, Santa Cruz, CA	Visualization and analysis of cancer genomics data using UCSC Xena 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; Visium; Chromium; CosMx; MerFISH
6077	Diego Alejandro Velarde, Joseph Valdes, Chunli Yan, Sarah Elmalh, Hannah Lee, Daniel James Mullen, Angie Moreno, Matthew A. Gladstone, JONATHAN CASTILLO, Crystal N. Marconett, Nicky Nie, Ming Li, W. Martin Kast, Ite A. Offringa	USC/Norris Comprehensive Cancer Center, Los Angeles, CA | University of California San Diego, San Diego, CA | USC - University of Southern California, Los Angeles, CA | | City of Hope Beckman Research Institute, Duarte, CA | Beckman Research Institute of The City of Hope, Glendale, CA | Keck School of Medicine of USC, Los Angeles, CA	A natural antibody response associated with improved survival of SCLC patients can be actively induced in a SCLC mouse model and leads to significantly improved survival 4/21/2026 2:00:00 PM | In Vivo Models 2: Genetically Engineered Mouse Models, PDXs, Syngeneic Models Open abstract	Visium
6116	Yang Liu, Akshaya S. Jadhav, Yuwen Pan, Jianlong Liao, Isha Khanduri, Yunhe Liu, Riham Katkhuda, Wei Lu, Kyung Serk Cho, Tieling Zhou, Baohua Sun, Mei Jiang, Sharia D. Hernandez, Idania Carolina Lubo Julio, Patrick Brennan, Guangsheng Pei, Kai Yu, Yibo Dai, Tian Chu, Fuduan Peng, Khaja Khan, Saxon Rodriguez, Ling Xia, Youming Guo, Alicia Mejia, Zhiming Tong, Sean W. Barnes, Ou Shi, Shreeya Indulkar, Alaa Mohamed, Natalie Wall Fowlkes, Timothy Newhook, Yun Shin Chun, Van K. Morris, David G. Menter, Dadi Jiang, Jean-Nicolas Vauthey, Ruoyan Li, Humam Kadara, Luisa M. Solis Soto, Scott Kopetz, Linghua Wang, Dipen M. Maru	The University of Texas MD Anderson Cancer Center, Houston, TX	Spatial multi-omics dissection of colorectal cancer micrometastasis 4/21/2026 2:00:00 PM | Metastasis and Organ-Specific Microenvironmental Evolution Open abstract	Visium
6158	Tadahito Yasuda, Mayu Yasuda, Atsuko Yonemura, Fabio de Mello, Feng Guo, Boping Jing, Hudie Li, Takatsugu Ishimoto, Yaoqi Alan Wang	Indiana University School of Medicine, Indianapolis, IN | The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan	Senescent tumor-associated macrophages promote peritoneal metastatic niche formation in gastric cancer 4/21/2026 2:00:00 PM | Metastatic Niches and Microenvironment Open abstract	Visium
6159	Ping Xu, Yuehui Zhao, Yun Yan, Rui Ye, Chenling Tang, Emi Sei, Shanshan Bai, Tuan Tran, Cole Ruoff, Christine Ly, Keyi Zhu, Miao Zhang, Bila A. Siddiqui, Sumit K. Subudhi, Paul Corn, Christopher J. Logothetis, Patricia Troncoso, Amado J. Zurita-Saavedra, Nicholas Navin	Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX | Department of Pathology, UT MD Anderson Cancer Center, Houston, TX | Department of Genitourinary Medical Oncology, UT MD Anderson Cancer Center, Houston, TX	Co-evolution of cancer cells and their microenvironment of primary and lymph node metastatic prostate cancer under androgen deprivation therapy 4/21/2026 2:00:00 PM | Metastatic Niches and Microenvironment Open abstract	Xenium; Visium
6187	Yajas Shah, Tianyou Luo, Christine M. Hoeman, Luca Lonini, Stanislaw Szydlo, Eduardo Diaz, Rossin Erbe, Matthew B. Maxwell, Michelle M. Stein, Andrew J. Sedgewick, Nicholas Rachell, Zachary Chelsky, Sonal Khare, Ryan D. Jones, Kate Sasser, Richard A. Klinghoffer, Justin Guinney, Chi-Sing Ho	Tempus AI, Chicago, IL	Elevating bulk sequencing with high-resolution spatial transcriptomics: A paired-data analysis of clinically-relevant spatial niches in CRC and NSCLC 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Visium
6188	Yun Yan, Yiyun Lin, Tapsi Kumar, Shanshan Bai, Aatish Thennavan, Jianzhuo Li, Tuan Tran, Min Hu, Mitchell Rao, Anna Casasent, Elizabeth Ravenberg, Gaiane Margishvili Rauch, Alyson Clayborn, Debu Tripathy, Alastair Thompson, Bora Lim, Lei Huo, Lei Huo, Stacy Moulder, Clinton Yam, Nicholas E. Navin	UT MD Anderson Cancer Center, Houston, TX | Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, TX	Decoding the archetypes and ecotypes of triple-negative breast cancer in responses to chemotherapy 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium; Visium
6204	Ryuta Watanabe, Kensuke Shishido, Shota Nobumori, Naoya Sugihara, Keigo Nishida, Haruna Arai, Takatora Sawada, Shunsuke Haga, Osuke Arai, Tomoya Onishi, Kenichi Nishimura, Tstsuya Fukumoto, Noriyoshi Miura, Mie Kurara, Riko Kitazawa, Yuki Miyauchi, Tadahiko Kikugawa, Takashi Saika	Department of Urology, Ehime University Graduate School of Medicine, Toon, Japan | Department of Analytical Pathology, Ehime University Graduate School of Medicine, Toon, Japan | Division of Diagnostic Pathology, Ehime University Hospital, Toon, Japan	Spatial transcriptomic dissection of TSC-associated angiomyolipoma reveals microenvironmental programs driven by mTORC1 dysregulation 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Visium
6211	Samuel Mwakisha Mwamburi, Jevon Layne, Niki Talebian, Ezra G. Baraban, Ashley Kiemen, Clayton C. Yates	Pathology, Johns Hopkins University School of Medicine, Baltimore, MD	AI-guided spatial multi-omics integration reveals immune and stromal heterogeneity underlying population disparities in prostate cancer. 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Visium
6212	Julia Louw, Kenan Zhang, Anna Corcoran, Elizabeth Owens, Jodie Jepson, Jose R. Conejo-Garcia, David M. Ashley, Kanish Mirchia, David R. Raleigh, Mustafa Khasraw	Duke University, Durham, NC | Duke University School of Medicine, Durham, NC | Duke University Medical Center, Durham, NC | UCSF, San Francisco, CA | University of California San Francisco, San Francisco, CA | Duke Cancer Institute, Durham, NC	Spatial immune and vascular remodeling defines recurrence in oligodendroglioma 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium; Visium
6214	Gaurav N. Joshi, Nicholas Sciascia, Michael Yang, Brenna Fearey, Junya Yoshioka, Fumiki Yanagawa	Nikon Bioimaging Lab, Nikon Instruments Inc, Lexington, MA	Mapping the tumor landscape: spatial multiomics reveals immune and stromal heterogeneity across early and late-stage NSCLC 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Visium
6316	Alexis Assante, Khosbayar Lkhagvadorj, Hyunmin Kim, Kimberly R. Jordan, Daniel T. Merrick, Robert L. Keith, York E. Miller, Moumita Ghosh	Pulmonary, Allergy and Critical Care Medicine, University of Colorado, Aurora, CO | Genetic and Genome Sciences, Case Western University, Cleveland, OH | Department of Immunology and Microbiology, University of Colorado, Aurora, CO | Department of Pathology, University of Colorado, Aurora, CO | Rocky Mountain Regional Veteran Affairs Medical Center, Aurora, CO	Accumulation of p21+ cells and enrichment of growth arrest signature in persistent high-grade premalignant lesions 4/21/2026 2:00:00 PM | Genomics, Proteomics, Biomarkers, and Risk Stratification Open abstract	Visium
6576	Chih-Hung Chung, Han-Hsun Yu, Muh-Hwa Yang	National Yang Ming Chiao Tung University, Taipei, Taiwan	Integrative spatial transcriptomics reveals EMT-driven immune regulatory programs underlying metastasis in HNSCC 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	Xenium; Visium; GeoMx
6667	Cindy Pamela Ulloa Guerrero, Michele Bortolomeazzi, Pooja Sant, Laura Schütze, Laura Giese, Denise Keitel, Julia Boehl, Robin Reschke, Jan-Philipp Mallm	Single-cell Open Lab, DKFZ German Cancer Research Center, Heidelberg, Germany | Max-Eder Research Group Reschke, University Hospital Heidelberg, Heidelberg, Germany	Integrated spatial transcriptomics and proteomics workflows for high-resolution multiomics analysis 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	Xenium; Visium
6668	Robbin Nameki, Jennifer Kinong, Chao-Hui Huang, Michelle Saul, Aakash Sur, Mehmet Tekman, Alexander Trageser, Wenjing Yang, Daniel Chawla, Greg Szeto, Arne Schmidt, Alberto Megina Gonzalo, Srishti Munjal Mehta, Nina Kozar-Gillan, Rosemarie Krupar, Sophie Laturnus, Cornelius Bohm, Marija Pezer, Gloria H.Y. Lin, Diane Fernandez, Keith Ching, Jadwiga R. Bienkowska, Thomas Powles, Craig B. Davis	Pfizer, Inc., San Diego, CA | Aignostics, Berlin, Germany | Experimental Cancer Medicine Centre, Barts Cancer Institute, London, United Kingdom	Spatial and transcriptomic remodeling of the tumor microenvironment following neoadjuvant atezolizumab in urothelial carcinoma: Insights from the ABACUS Study 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	Visium
6788	B. Zhu, M. Aminu, Y. Tian, S.-W. Lu, O. Shi, W. Lu, H. Chen, H. Li, Z. Wei, M. B. Nilsson, L. Solis Soto, F. P. Andrew, D. L. Gibbons, J. V. Heymach, C. Cheng, J. Wu, J. Zhang; UT MD Anderson Cancer Center, Houston, TX, The University of Texas MD Anderson Cancer Center, Baylor College of Medicine, Houston, TX		Spatial single-cell analysis reveals stage-dependent mechanisms of anti-IL-1β therapy in lung adenocarcinoma 4/21/2026 3:20:00 PM | Inflammation and Immunity in Cancer Progression Open abstract	Xenium; Visium
6853	Xiao Wang, Nan Zhang, Chi Zhang, Sha Cao	Indiana University, Bloomington, IN | Fudan University, Shanghai, China | Knight Cancer Institute, Oregon Health & Science University, Portland, OR | Biomedical Engineering, Oregon Health and Science University, Portland, OR	A segmentation-free method for modeling high-resolution spatial transcriptomics at the molecule level 4/22/2026 9:00:00 AM | Mathematical Modeling and Statistical Methods Open abstract	Xenium; Visium
6862	Dongjoo Lee, Sungwoo Bae, Yeonjae Jung, Kwon Joong Na, Hongyoon Choi	Portrai, Inc., Seoul, Korea, Republic of	A scalable workflow for in silico TMA construction and groupwise comparison of spatial transcriptomic data for analyzing tumor microenvironment 4/22/2026 9:00:00 AM | Network Biology and Precision Medicine Open abstract	Visium
6895	Yufeng He, Yanping Zhao, Rui Zhang, Heli Yang, Zhaode Bu, Yuan Luo, Deng Pan, Zexian Zeng	Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China | Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China | Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Peking University, Beijing, China | Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL | Tsinghua-Peking Center for Life Sciences, Department of Basic Medical Sciences, Tsinghua University, Beijing, China	DISSECT integrates cytological images and spatial transcriptomics for cell segmentation 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	Xenium; Visium; CosMx
6903	Sungwoo Bae, Hongyoon Choi, Dongjoo Lee, Daeseung Lee	Portrai, Inc., Seoul, Korea, Republic of	A transcript-only framework for pseudocell boundary inference in high-resolution spatial transcriptomics 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	Visium
6914	Xinyu Hu, Fengwei Zhan, Lixia C. Wu, Jose Gonzalez, Chuhanwen Sun, Rachel Ofer, Tyler Tran, Michael Verzi, Jiekun Yang	Department of Genetics, Rutgers University, New Brunswick, NJ | Quantitative Biomedicine Program, Rutgers University, New Brunswick, NJ	STCS: Spatial transcriptomics cell segmentation outperforms existing methods on multiple slides 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	Xenium; Visium
7399	Haley du Bois, Alberto Chaves, Ryan Bishop, Dina Atta, Jeremy Steven Frieling, Karl Nyman, Tao Li, Mostafa Nasr, Conor C. Lynch	Moffitt Cancer Center, Tampa, FL | College of Engineering, University of South Florida, Tampa, FL | H. Lee Moffitt Cancer Center and Research Institute and the University of South Florida, Tampa, FL | Tumor Microenvironment & Metastasis, Moffitt Cancer Center, Tampa, FL	Eosinophils promote an immunosuppressive bone marrow microenvironment in multiple myeloma 4/22/2026 9:00:00 AM | Functional and Spatial Regulation of Immune Evasion and Anti-Tumor Immunity Open abstract	Visium
7503	Shuichi Watanabe, Yoshiyuki Suehara, Masachika Ikegami, Soohwan Park, Yo Kimura, Toshihide Ueno, Takuo Hayashi, Hiroyuki Mano, Kazuya Takamochi, Shinji Kohsaka	Division of Cellular Signaling, National Cancer Center Japan, Tokyo, Japan | Department of Diagnostic Pathology, Juntendo University Hospital, Tokyo, Japan | National Cancer Center Japan, Tokyo, Japan | General Thoracic Surgery, Juntendo University Hospital, Tokyo, Japan	Spatio-temporal analysis of EGFR inhibitor resistant tumor epithelial clusters 4/22/2026 9:00:00 AM | Tumor Heterogeneity Open abstract	Visium
7732	Maria F. Mercogliano, Nadine Schrode, Kristin Beaumont, Roxana Schillaci	Laboratorio de Inmunología Tumoral, Instituto de Biología y Medicina Experimental, Buenos Aires, Argentina | Center for Advanced Genomics Technology, Icahn School of Medicine at Mount Sinai, New York, NY | Icahn School of Medicine at Mount Sinai, New York, NY | Laboratorio de Inmunología Tumoral, Instituto de Biología y Medicina Experimental, Buenos Aires, Argentina	A stromal-immune spatial transcriptomic signature associated with MUC4 identifies potential biomarkers of trastuzumab resistance in HER2-positive breast cancer 4/22/2026 9:00:00 AM | Biomarkers Predictive of Therapeutic Benefit 6 Open abstract	Visium
7767	Sophia A. Paxton, Corinne H. Strawser, Lakshmi Prakruthi Rao Venkata, Elizabeth A. R. Garfinkle, James M. Markert, Katherine E. Miller, Kevin A. Cassady, Elaine R. Mardis	The Steve and Cindy Rasmussen Institute for Genomic Medicine, The Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH | Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL | Center for Childhood Cancer Research, The Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH	Spatial profiling of the tumor immune microenvironment following oncolytic herpes simplex virus treatment in glioblastoma 4/22/2026 9:00:00 AM | Immune Response to Therapies Open abstract	Visium
	Jean-Philippe Vert. Bioptimus, Paris, France		M-Optimus-1: a multimodal foundation model unifying H&E, bulk RNA-seq, scRNA-seq, and visium spatial transcriptomics for cancer research 4/21/2026 10:00:00 AM | M-Optimus-1: A Multimodal Foundation Model Unifying H&E, Bulk RNA-seq, scRNA-seq, and Visium Spatial Transcriptomics for Cancer Research Open abstract	Visium
LB122	Grégoire Marret, Jinsu An, Farnoosh Abbas Aghababazadeh, Kewei Ni, Lucas Penny, Martin Hyrcza, Ben X. Wang, Enrique Sanz-Garcia, Anna Spreafico, Giselle Boukhaled, Simone Stone, Aaron R. Hansen, Troy Ketela, Benjamin Haibe-Kains, Scott V. Bratman, Pinaki Bose, Lillian L. Siu	Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, Canada | Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada | Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, Canada | Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada | Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada	Dynamic interactions of spatially organized tumor, stromal and immune cellular niches predict outcome to immune checkpoint blockade (ICB) in recurrent or metastatic head and neck squamous cell carcinoma (RM-HNSCC) 4/20/2026 9:00:00 AM | Late-Breaking Research: Clinical Research 2 Open abstract	Visium
LB163	Dor Simkin, Thomas F. Barrett, Lingling Zhang, Michael J. Moore, Alissa R. Greenwald, Noam G. Darnell, Michael Mints, Salma Ramadan, Victoria Yu, Riley DZ Mullins, Jesse Zaretsky, Porter Bischoff, Douglas Adkins, Wade L. Thorstad, Sana D. Karam, Randall C. Paniello, Jason T. Rich, Ryan S. Jackson, Patrik Pipkorn, Paul A. Zolkind, Guangyong Peng, R. Alex Harbison, Rebecca Chernock, Anuraag S. Parikh, Sidharth V. Puram, Itay Tirosh	Weizmann Institute of Science, Rehovot, Israel | Washington University School of Medicine, St. Louis, MO | Columbia University Irving Medical Center, New York, NY	Spatial analysis of head and neck cancer reveals two ecosystems with distinct modes of epithelial-to-mesenchymal transition 4/20/2026 9:00:00 AM | Late-Breaking Research: Bioinformatics, Computational Biology, Systems Biology, and Convergent Science 1 Open abstract	Visium
LB175	Andrew T. Wang, Saugato R. Dhruba, Emma M. Campagnolo, Kun Wang, Danh-Tai Hoang, Eldad D. Shulman, Eytan Ruppin	NIH-NCI, Bethesda, MD	Weakly supervised deep learning enables spatially resolved cell type inference from H&E histopathology 4/20/2026 9:00:00 AM | Late-Breaking Research: Bioinformatics, Computational Biology, Systems Biology, and Convergent Science 1 Open abstract	Visium
LB191	Jiaqian Luo, Sizhi P. Gao, Jacob E. Tallman, Fengshen Kuo, Merve Basar, Cansu Yol, Syed M. Alam, Hui Jiang, Xinran Tang, Alejandra Lopez Rojas, Ecenur Turkay, Jonathan E. Rosenberg, Iyer Gopakumar, Eugene J. Pietzak, David B. Solit, Hikmat Al-Ahmadie	Memorial Sloan Kettering Cancer Center, New York, NY	Decoding metastasis and therapy resistance in sarcomatoid bladder cancer 4/20/2026 2:00:00 PM | Late-Breaking Research: Experimental and Molecular Therapeutics 2 Open abstract	Visium
LB237	Wei Zhao, Aaron Rozeboom, Phuc H. Hoang, Tam-Anh Tran, Maria Teresa Landi	National Cancer Inst. Div. of Cancer Epidemiology & Genetics, Bethesda, MD | Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD	High-resolution spatial transcriptomics identifies unique spatial programs in lung adenocarcinoma from never smokers 4/20/2026 2:00:00 PM | Late-Breaking Research: Tumor Biology 1 Open abstract	Xenium; Visium
LB238	Danyelle Hill, Yuxin Jin, Javier Arias-Stella, Joseph Carlson, David Craig, Rania Bassiouni, John Carpten	Beckman Research Institute of The City of Hope, Duarte, CA | The City of Hope, Duarte, CA	Spatial transcriptomics identifies distinct molecular and immune pathways in endometrial cancer in African American women 4/20/2026 2:00:00 PM | Late-Breaking Research: Tumor Biology 1 Open abstract	Visium
LB306	Sylvia Burris, Gurdeep Singh	George Mason University, Fairfax, VA | University of New Mexico Health Sciences Center, Albuquerque, NM	Spatial transcriptomics reveals primary-site endothelial EMT reprogramming that drives immunosuppression in metastatic uveal melanoma and predicts poor survival 4/21/2026 9:00:00 AM | Late-Breaking Research: Tumor Biology 2 Open abstract	Visium

Abstract #	Authors	Affiliation	Title / Session	Products
1053	Inaki Comino-Mendez, Maria Rosario Chica-Parrado, María Elena Quirós-Ortega, Ana Godoy-Ortiz, Maria Emilia Dominguez-Recio, Esperanza López-López, María Victori Ortega-Jiménez, Martina Alvarez, Javier Pascual, Enrique de Alava, Emilio Alba	Institute of Biomedical Research of Malaga (IBIMA), Malaga, Spain | Hospital Universitario Virgen de la Victoria, Malaga, Spain | Department of Normal and Pathological Cytology and Histology, Institute of Biomedicine of Sevilla (IBiS), Sevilla, Spain	Single-cell immune profiling reveals biomarkers of pembrolizumab response in early triple-negative breast cancer 4/19/2026 2:00:00 PM | Biomarkers Predictive of Therapeutic Benefit 2 Open abstract	Chromium
1633	Simon E. Plyte, Marie Fraudeau, Dorothee Winterberg, Claire Germain, Camille Rousseau, Maxime Audin, Alexandre Ivagnes, Sothea Touch Dumoitier, Sarah Ducellier, Lise Fenou, Hans Heinrich Oberg, Pierre Emmanuel Gerard, Isabelle Teulon, Daniela Wesch, Matthias Peipp, Julie Prigent	Biomunex Pharmaceuticals, Paris, France | Universitats Klinikum Schleswig-Holstein,, Kiel, Germany | IRCM, Univ Montpellier, ICM, INSERM, Montpellie, France	MAIT engagers: Avoiding Treg suppression to deliver stronger activity in solid tumors. 4/20/2026 9:00:00 AM | T Cell Engagers 1 Open abstract	Chromium
2221	Youngtaek Kim, Gang-Taik Lee, Dong Kwon Kim, JuHyeon Lee, So Young Park, Jae Hwan Kim, Hyun Jung Yoo, Byoung Chul Cho	Yonsei University College of Medicine, Seoul, Korea, Republic of | Department of Research Support, Yonsei Biomedical Research Institute, Seoul, Korea, Republic of | Yonsei New Il Han Institute for Integrative Lung Cancer Research, Seoul, Korea, Republic of	Tumor-associated CD207+ cDC2 drives TLS formation via TNF family cytokines in non-small cell lung cancer 4/20/2026 9:00:00 AM | Tertiary Lymphoid Structures in Cancer Open abstract	Chromium
2823	Junting Lu, Jinghui Xiu, Ce Zhong, Wentao Li, Wei Yun, Tan Pang, Jingqi Huang	Pharmacology, Pharmaron, Beijing, China	Single-cell RNA-seq reveals insights into the effects of immune checkpoint inhibitors 4/20/2026 2:00:00 PM | Immune Checkpoints Open abstract	Chromium
4692	Rebekah Gridley, Palakshi Bandapalli, Sharmila Govindaraj, Siddhant Meshram, Suvo Chatterjee, Gurdeep Singh, Arunkumar Ganesan	Cell Biology & Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM | Department of Epidemiology and Biostatistics, Indiana University, Bloomington, IN	Environmental toxin-induced m6A RNA modification promotes R-loop accumulation and chromosomal instability 4/21/2026 9:00:00 AM | Insights into Genomic Instability Open abstract	Chromium
4736	Diddier Prada, Manish Arora, Julio landero, Jamshid Abdul Ghafar, Rachel Brody, Oscar Arrieta, Fred R. Hirsch	Icahn School of Medicine at Mount Sinai, New York, NY | Mt. Sinai Medical Center Tisch Cancer Institute, New York, NY | Instituto Nacional de Cancerología (INCan), Mexico City, Mexico	Trace metal signatures in non-small cell lung cancer: A pilot study of patients attended at Mount Sinai Hospital in New York City 4/21/2026 9:00:00 AM | Metabolic Features of Thoracic and Urologic Cancers Open abstract	Chromium
5524	Mary Goldman, Brian Craft, Cally Lin, Jingchun Zhu, David Haussler	UC Santa Cruz Genomics Institute, Santa Cruz, CA | Stanford University, San Francisco, CA | Investigator/Distinguished Professor, Ctr. For Bio. Sci. & Eng., UC Santa Cruz, Santa Cruz, CA	Visualization and analysis of cancer genomics data using UCSC Xena 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; Visium; Chromium; CosMx; MerFISH
5922	Yujin Lee, Moray J. Campbell, James C. Fleet	Dept. of Nutritional Sciences, The University of Texas at Austin, Austin, TX | Karmanos Cancer Institute, Wayne State University, Detroit, MI	Single-cell mapping of the colon epithelium reveals a pre-malignant stem cell that defines early transformation risk 4/21/2026 2:00:00 PM | Genetic and Transcriptomic Dissection of Cancer Evolution Open abstract	Chromium
6569	Vince Kornel Grolmusz, Klaudia Horti-Oravecz, István Kelemen, István Likó, Anikó Bozsik, Tímea Pócza, Janos Papp, Szonja Polett Pósa, Lorinc S. Pongor, Henriett Butz, Attila Patócs	National Institute of Oncology Hungary, Budapest, Hungary | Hungarian Center of Excellence for Molecular Medicine, Szeged, Hungary	Single-cell transcriptomics reveal functional interaction between CD4+ T cells and B cells driving the activated peripheral immune phenotype in healthy women living with germline pathogenic BRCA1 variants 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	Chromium
6718	Abraham A. Hakim, Lisa Kenney, Nivedita Mohan Ratnam, Jared J. Gartner, Ian S. Goldlust, Aarushi Bhasin, Brian Bui, Nicholas D. Klemen, Steven A. Rosenberg, Frank J. Lowery	NIH-NCI, Bethesda, MD | Laboratory of Integrative Cancer Immunology (LICI), Center for Cancer Research, Bethesda, MD | National Cancer Institute, Bethesda, MD | National Institutes for Health, Bethesda, MD | Surgery Branch, NIH-NCI, Bethesda, MD | Surgery Branch, National Cancer Institute, Bethesda, MD	Identifying new cell surface markers of T-cell reactivity through single cell transcriptomic analysis 4/21/2026 2:00:00 PM | Vaccines and Other Immunomodulatory Agents Open abstract	Chromium
7012	Qianyun Luo, Rebecca LaRue, Enoc Granados Centeno, Kyra Bergerud, Michael Farrar, Sean Tracy	University of Minnesota, Minneapolis, MN	Single-cell multi-omics identifies MRD-associated Tr1-like CD4 cells in B-ALL 4/22/2026 9:00:00 AM | Tumor-induced Immune Suppression Open abstract	Chromium

Abstract #	Authors	Affiliation	Title / Session	Products
12	Francisco G. Carranza, Brigette Waldrup, Yuxin Jin, Yonatan Amzaleg, David Craig, John Carpten, PE-CGS Network, Enrique I. Velazquez Villarreal	Department of Integrative Translational Sciences, City of Hope National Medical Center, Duarte, CA	Integrative spatial multi-omics profiling enhanced by artificial intelligence reveals ancestry-associated molecular features in early-onset colorectal cancer among Southern California patients 4/19/2026 2:00:00 PM | AACR Project GENIE: Predictive Models and AI Open abstract	Visium
44	Alexander V. Lobanov, Hani Jieun Kim, Sehrish Kanwal, Kate Harvey, John Reeves, Marcel Batten, Beata Kiedik, Daniel L. Roden, Mun N. Hui, Kym Pham Stewart, Oliver Hofmann, Sandra O’Toole, Elgene Lim, Sean M. Grimmond, Alexander Swarbrick, Charles M. Perou	UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC | Garvan Institute of Medical Research, Darlinghurst, Australia | Collaborative Centre for Genomic Cancer Medicine, Parkville, Australia | Chris O'Brien Lifehouse, Camperdown, Australia	scSubtype2.0: Predictor of breast cancer molecular subtypes at single cell resolution 4/19/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 1 Open abstract	-
50	Emmanuel S. Spanos, Meng Wang, Amin Sabet, Esther Redin, Charles M. Rudin, Joseph Chan	Physiology, Biophysics, and Systems Biology, Weill Cornell Grad. School of Medical Sci., New York, NY | Memorial Sloan Kettering Cancer Center, New York, NY	Spatial transcriptomics uncovers patterns of transcriptional reprogramming and immune evasion in small cell lung cancer 4/19/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 1 Open abstract	Xenium
94	Erin L. Brown, Wubing Zhang, Abul Usmani, Noah Earland, Ayesha Hashmi, Chibuzor Olelewe, Anushka Viswanathan, Pradeep S. Chauhan, Minji Kang, Chloé B. Steen, Hyun Soo Jeon, Susanna Avagyan, Irfan Alahi, Nicholas P. Semenkovich, Matteo Bergsagel, Janella C. Schwab, Chloe M. Sachs, Kaushal Parikh, Faridi Qaium, Peter K. Harris, Antonella Bacchiocchi, Qingyuan Cai, Andrew J. Gentles, Rondell P. Graham, Peter C. Lucas, Ryan C. Fields, Jacob J. Orme, Aaron S. Mansfield, Mario Sznol, Ruth Halaban, David Y. Chen, Aaron M. Newman, Aadel A. Chaudhuri	Stanford University School of Medicine, Stanford, CA | Washington University in St. Louis, St. Louis, MO | Mayo Clinic, Rochester, MN | Oslo University Hospital and University of Oslo, Oslo, Norway | Medical College of Wisconsin, Milwaukee, WI | Yale University School of Medicine, New Haven, CT | Columbia University, New York, NY | University of Rochester School of Medicine, Rochester, NY	Liquid biopsy profiling of the tumor microenvironment to determine response to immunotherapy regimens across solid tumors 4/19/2026 2:00:00 PM | Liquid Biopsy: Multi-Analyte and Multi-Omic Open abstract	Visium
495	Houlin Yu, Guoping Wang, Stephanie Yaung, Heejo Choi, Megan Rogers-Peckham, Michael Kartje, Matthew Rees, Paul Lund, Brian Haas, Charlotte Yang, Laura Doherty, Lacey McGee, Kendall Berg, Cynthia Cech, Salka Barrett, Anasha Arryman, Joanne Leadbetter, Taylor Lehmann, John Mannion, Chen Zhao, Marc Prindle, Melud Nabavi, Carolyn Morrison, Peter Smibert, Kit Nazor, Todd Golub, Catarina D. Campbell, Jennifer Roth, Niall Lennon, Victoria Popic, Dean Procter, Kokoris Mark, Aziz M. Al'Khafaji	Broad Institute of MIT and Harvard, Cambridge, MA | Roche Sequencing Solutions, Inc, Santa Clara, CA | Roche Sequencing Solutions, Inc, Seattle, WA | 10x Genomics, Pleasanton, CA | Proteintech Genomics, San Diego, CA	Single-cell multiomic drug response profiling of PRISM-multiplexed cancer cell lines sequenced with SBX 4/19/2026 2:00:00 PM | Genomic Dissection to Define Novel Therapeutic Strategies Open abstract	-
643	Abbe Pannucci, Elina Mukherjee, Jessica D. Daley, Shireen Sita Ganapathi, Elissa Boguslawski, Lea Surrey, Lauren Gutstein, Patrick Azar, Emily Stockfisch, Azfar Neyaz, Ivy John, Jennifer Picarsic, Yutaro Tanaka, Byron Butaney, Riaz Gillani, Brian D. Crompton, Katherine A. Janeway, Jaclyln Taroni, Jessica Davis, Damon Reed, Adam Shlien, Theodore W. Laetsch, Rajen Mody, Clémence Henon, Thomas G. Grünewald, Elizabeth R. Lawlor, Filemon Dela Cruz, Patrick J. Grohar, Jovana Pavisic, Ally Hawkins, Anthony R. Cillo, Kelly M. Bailey	University of Pittsburgh, Pittsburgh, PA | UPMC, Pittsburgh, PA | Seattle Children's Research Institute, Seattle, WA | University of Michigan, Ann Arbor, MI | Children's Hospital of Philadelphia, Philadelphia, PA | Indiana University, Indianapolis, IN | Memorial Sloan Kettering Cancer Center, New York, NY | The University of Pittsburgh School of Medicine, Pittsburgh, PA | Dana-Farber Cancer Institute, Boston, MA | The Childhood Cancer Data Lab, Wynnewood, PA | Graduate Student, Dept. of Genetics & Genome Bio., The Hospital for Sick Children, Toronto, ON, Canada | Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany | University of Michigan Medicine, Ann Arbor, MI | Memorial Sloan Kettering, New York, NY | Mayo Clinic, Rochester, MN	The Sean Karl Cohort: An international single-cell RNAseq study of paired patient Ewing sarcoma specimens 4/19/2026 2:00:00 PM | Developmental Origins, Drivers, and Heterogeneity in Pediatric Cancer Open abstract	-
667	Maxim Norkin, Jonathan Bac, Louis McConnel, Sylvie Andre, Marina Alexandra Gaveta, Joerg Huelsken, Marianna Rapsomaniki, Raphael Gottardo, Krisztian Homicsko	Oncology, CHUV, Centre hospitalier universitaire vaudois, Lausanne, Switzerland | EPFL, Lausanne, Switzerland	Mapping and targeting spatial heterogeneity in CRC through patient-derived organoids 4/19/2026 2:00:00 PM | Ex Vivo Systems: Patient-Derived, Patient-Specific Tumor Cultures Open abstract	Xenium
898	Nicole Mavingire, Abdulrahman M. Dwead, Joy Solomon, Janelle Moore, Moyinoluwa Adeniyi, Odunayo Oluokun, Jabril R. Johnson, Estefania Labanca, Peter Shepherd, Mya Walker, Isaiah Sailors, Serene Dowiri, Greisha L. Ortiz Hernandez, Jillian C. McDonough, Diana LeVasseur, Jazlyn Farlough, Justin Tran, Frank Myers, Fornati Bedell, Zhirong Yin, Rachel Martini, Melissa B. Davis, Clayton C. Yates, K. Sean Kimbro, Rick A. Kittles, Tanya Dorff, Cristina Magi-Galluzzi, Soroush Rais-Bahrami, Firas Kobeissy, Yehia Mechref, Leanne Woods-Burnham	Morehouse School of Medicine, Atlanta, GA | Texas Tech University, Lubbock, TX | UT MD Anderson Cancer Center, Houston, TX | City of Hope National Medical Center, Duarte, CA | Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD | The University of Alabama at Birmingham, Birmingham, AL | Wake Forest University School of Medicine, Winston-Salem, NC	HER2 as a therapeutic target in prostate cancer: Multi-omic and spatial insights across genetic ancestries 4/19/2026 2:00:00 PM | Survivorship Research Addressing Cancer Disparities Open abstract	Xenium
931	Michelle M. Leung, Maria Zagorulya, Tej Pandya, Marcellus Augustine, Anthony J. Griffen, Alix Le Marois, Sophia Ward, Hubert Slawinski, Alejandro Suárez-Bonnet, Simon L. Priestnall, Alexandros Hardas, Erik Sahai, Lindsay M. LaFave, Eva Gronroos, Nicholas McGranahan, William Hill, Clare Weeden, Charles Swanton	University College London (UCL) Cancer Institute, London, United Kingdom | The Francis Crick Institute, London, United Kingdom | Albert Einstein College of Medicine, New York, NY | Royal Veterinary College, London, United Kingdom	Air pollutants remodel mutant epithelia toward a convergent lung adenocarcinoma progenitor state 4/19/2026 2:00:00 PM | Cancer in the Community: Epidemiology, Experimental Knowledge, Action, and Communication Open abstract	-
935	Christopher Mellor, Saeideh Azad, Nicholas Cheng, Brandon James, Vicky A. Simon, Olga V. Malysheva, Guillermo Burgos Barragan, John Blenis, Martha S. Field, Meng Wang	Division of Nutritional Sciences, Cornell University, Ithaca, NY | Weill Cornell Medical College, New York, NY | Professor of Pharmacology, Weill Cornell Medical College, New York, NY	Nutritional disruption of folate homeostasis triggers an endogenous genotoxic carcinogen 4/19/2026 2:00:00 PM | Cancer in the Community: Epidemiology, Experimental Knowledge, Action, and Communication Open abstract	-
1053	Inaki Comino-Mendez, Maria Rosario Chica-Parrado, María Elena Quirós-Ortega, Ana Godoy-Ortiz, Maria Emilia Dominguez-Recio, Esperanza López-López, María Victori Ortega-Jiménez, Martina Alvarez, Javier Pascual, Enrique de Alava, Emilio Alba	Institute of Biomedical Research of Malaga (IBIMA), Malaga, Spain | Hospital Universitario Virgen de la Victoria, Malaga, Spain | Department of Normal and Pathological Cytology and Histology, Institute of Biomedicine of Sevilla (IBiS), Sevilla, Spain	Single-cell immune profiling reveals biomarkers of pembrolizumab response in early triple-negative breast cancer 4/19/2026 2:00:00 PM | Biomarkers Predictive of Therapeutic Benefit 2 Open abstract	Chromium
1098	Jeremy L. Davis, Amber Famiglietti, Yunhe Liu, Rachael Belcher, Sun A Kim, Baktiar O. Karim, Donna Butcher, Linghua Wang	University of Maryland School of Medicine, Baltimore, MD | Department of Surgery, Georgetown University, Washington, DC | UT MD Anderson Cancer Center, Houston, TX | Laboratory of Pathology, National Cancer Institute, Baltimore, MD | Frederick National Laboratory for Cancer Research, Frederick, MD	Discrete precancer subtypes and biomarkers of cancer progression identified with spatiotemporal analysis of CDH1-driven diffuse gastric cancer 4/19/2026 2:00:00 PM | Early Detection Biomarkers 1 Open abstract	Xenium
1209	Diana Bell, Randal S. Weber, Miao Zhang, Michelle Afkhami, Raja R. Seethala	University of Pittsburgh, Pittsburgh, PA | University of Texas MD Anderson Cancer Center, Houston, TX | City of Hope, Duarte, CA	FGFR2 translocated sinonasal adenocarcinoma: A biphasic seromucinous adenocarcinoma with a distinctive and targetable molecular phenotype 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1210	Kazutaka Otsuji, Tomo Osako, Yoko Takahashi, Chikako Shibata, Sumito Saeki, Asumi Iesato, Tetsuo Noda, Kengo Takeuchi, Takayuki Ueno, Reo Maruyama	NEXT-Ganken Program, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Division of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Breast Oncology Center, Cancer Institute Hospital of JFCR, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Division of Cancer Epigenomics, Cancer Institute, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan | Director's room, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan	Integrated spatial and single-cell profiling uncovers a pre-existing, treatment-resistant subclone that drives early local relapse in luminal breast cancer 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium
1211	Changhee Park, Minki Choi, Jiwon Koh, Sungwoo Bae, Hongyoon Choi, Kwon Joong Na, Dae-Won Lee, Kyung-Hun Lee, Han Suk Ryu, Seock-Ah Im	Seoul National University Hospital, Seoul, Korea, Republic of | Pathology, Asan Medical Center, Seoul, Korea, Republic of | Pathology, Seoul National University Hospital, Seoul, Korea, Republic of | Portrai Inc., Seoul, Korea, Republic of	Spatial transcriptomics uncovers pharmacokinetic barriers and tumor-intrinsic determinants of resistance to trastuzumab deruxtecan in breast cancer 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1212	Whitney Tamaki, Daniel L. Kerr, Wei Wu, Grant Eilers, Anatoly Urisman, Yu-Ting Chou, Philippe Gui, Shigeki Nanjo, Johannes Ruediger Kratz, David Jablons, Trever G. Bivona, Collin M. Blakely	UCSF, San Francisco, CA | University of Washington, Seattle, WA | Anatomic Pathology, UCSF, San Francisco, CA | Kanazawa Univ. Hospital, Kanazawa, Japan | Clinical Fellow, Medical Oncology, UCSF, San Francisco, CA	Spatial transcriptomics reveals distinct SPP1-CD44 signaling networks in neoadjuvant osimertinib treated EGFR mutant non-small cell lung cancer 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1215	Prachi Bhave, Marie Trussart, Anthony T. Papenfuss, Grant A. McArthur	The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia | Walter & Eliza Hall Institute of Medical Research, Melbourne, Australia | Peter MacCallum Cancer Centre, Melbourne, Australia	Spatial transcriptomic analysis of primary melanomas with extreme clinical outcomes 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Visium
1223	Nicholas E. Bingham, Julie R. Boiko, Daniel C. Jones, Daniel Wong, Tiffany Khong, Sridurga Mithraprabhu, Kathleen S. Ensbey, Anna E. Elz, Evan W. Newell, Andrew Spencer, Geoffrey R. Hill	Australian Centre for Blood Diseases, Alfred Health - Monash University, Melbourne, Australia | Translational Science and Therapeutics Division, Fred Hutchison Cancer Centre, Seattle, WA | Vaccine and Infectious Diseases Division, Fred Hutchison Cancer Centre, Seattle, WA | Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Centre, Seattle, WA	Spatial transcriptomics identifies a suppressive T-cell excluded tumour microenvironment in extramedullary multiple myeloma 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium
1362	Y. Jiang, M. Wu, U. Saran, L. Campos Clemente, S. Jiang, A. Ghosh, I. Flores, D. Morales, W. Lu, K. Khan, L. Zhang, L. Maren Solis Soto, I. Wistuba, M. Gyu Lee, K. Rai; UT MD Anderson Cancer Center, Houston, TX, Baylor College of Medicine, Houston, TX		KMT2D is a master epigenetic regulator of lineage plasticity in lung squamous cell carcinoma 4/19/2026 4:35:00 PM | Advances in Cancer Epigenetics Open abstract	-
1432	Lucio Queiroz, Karnika Singh, Wikum Dinalankara, Luigi Marchionni	Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY	Single-cell-derived gene-pair classifiers for prostate cancer prognostication 4/20/2026 9:00:00 AM | Application of Bioinformatics to Cancer Biology 2 Open abstract	-
1476	Steven Yan, Limin Jiang, Yan Guo	University of Miami Miller School of Medicine, Miami, FL | University of Miami, Miami, FL	Improve spatial transcriptomic data with integrated hybrid transformer and graph convolutional networks 4/20/2026 9:00:00 AM | Integrative Computational Approaches 1 Open abstract	Xenium; Visium; CosMx
1967	Kimberly A. Holden, Ashraf Shabaneh, Dennis D. Krutkin, Adib Shafi, Tong Liu, Kerry D. Fitzgerald, Eyad Almasri, Yuanyu Cao, Xiaojun Guan, Graham McLennan, Nathan Faulkner, Shakti Ramkissoon, Marcia Eisenberg, Brian Caveney, Eric Severson, Taylor J. Jensen, Jonathan Williams	Labcorp, San Diego, CA | Labcorp, Durham, NC	Methylation-based classification of circulating tumor DNA using enzymatic methyl-seq in a pan-cancer clinical cohort 4/20/2026 9:00:00 AM | DNA Methylation Open abstract	-
1975	Swanand Rakhade, Mamie Wang, Lena Morrill Gavarró, Emmanuel Spanos, Alvaro Quintanal-Villalonga, Amin Sabet, Parvathy Manoj, Rishika Giri, Ronan Chaligné, Xinjun Wang, Helena A. Yu, Esther Redin, Dana Pe'er, Charles M. Rudin, Joseph Chan	Memorial Sloan Kettering Cancer Center, New York, NY	Genomic drivers of plasticity in transformed small cell lung cancer 4/20/2026 9:00:00 AM | Genomic Drivers of Cancer Pathogenesis Open abstract	-
2000	Rania Bassiouni, Yuxin Jin, Lee D. Gibbs, Jing Qian, Solomon O. Rotimi, Heather Miller, Michelle G. Webb, David W. Craig, Javier Arias-Stella, Lynda Roman, John D. Carpten	City of Hope, Duarte, CA | University of Southern California, Los Angeles, CA	A spontaneous CTNNB1 driver mutation reversion in a primary ovarian clear cell carcinoma 4/20/2026 9:00:00 AM | Genomic Drivers of Cancer Pathogenesis Open abstract	-
2092	Liang Liu, Pengbo Zhang, Enzo Palma, Ashley Ballard, Lance Miller, Gregory Hawkins, Cristina M. Furdui, Edward Levine, Alberto de Hoyos, Wencheng Li, Fang-Chi Hsu, Ralph D'Agostino, David Foureau, Wei Zhang	Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC | Atrium Wake Forest Baptist Comprehensive Cancer Center, Winston Salem, NC | Biochemistry, Wake Forest University School of Medicine, Winston Salem, NC | General Surgery, Wake Forest University School of Medicine, Winston Salem, NC | Cardiothoracic Surgery, Wake Forest University School of Medicine, Winston Salem, NC | Pathology, Wake Forest University School of Medicine, Winston Salem, NC | Biostatistics and Data Science, Wake Forest University School of Medicine, Winston Salem, NC | Cancer Medicine, Wake Forest University School of Medicine, Winston Salem, NC	Single-cell RNA sequencing reveals ancestry-associated molecular and cellular immunosuppressive features in non-small cell lung cancer 4/20/2026 9:00:00 AM | Aging and Host Determinants of Tumor Progression: The Macroenvironmental Axis Open abstract	-
2117	Valentina Opazo-Mellado, Maria Jose Oviedo, Diego Figueroa, Carlos Perez, Laura Hernandez, Joanna Phillips, Jeroen Roose, Hugo Gonzalez	Tumor Microenvironment and Metastasis Laboratory, Centro Basal Ciencia & Vida, Fundación Ciencia y Vida., Santiago, Chile | Department of Neurological Surgery, University of California San Francisco, San Francisco, CA | Department of Anatomy, University of California San Francisco, USA., San Francisco, CA | Tumor Microenvironment and Metastasis Laboratory, Centro Basal Ciencia & Vida, Fundación Ciencia y Vida; Universidad San Sebastian., Santiago, Chile	Single cell chromatin accessibility profiling of human metastatic tumor cells 4/20/2026 9:00:00 AM | Characterization of Metastases by Imaging and Profiling Open abstract	-
2173	Brian Ragaishis, Andrei Molotkov, Shruti Bansal, Krishan Saini, Meirdan Palihati, Chelsea Rahiman, Courtney Buress, Jasleen Kaur Virk, Mikhail Doubrovin, Catherine Spina	Radiation Oncology, Columbia University Irving Medical Center, New York, NY | Columbia University Irving Medical Center, New York, NY	Development of novel syngeneic mouse models of mHSPC and mCRPC for evaluation of radiopharmaceuticals on the immune tumor microenvironment (TME) 4/20/2026 9:00:00 AM | In Vivo Models 1: Mouse, Zebrafish, and Alternative Species Open abstract	-
2201	Maria Moozhiyil Korah, James P. Agolia, Biren Reddy, Renceh A. B. Flojo, Amanda Gonçalves, Lilin Wang, Rosyli F. Reveron-Thornton, Chuner Guo, Beatrice Sun, Amanda R. Kirane, George Poultsides, Deshka Foster, R. Stephanie Huang, Gregory W. Charville, Michael T. Longaker, Daniel Delitto	Stanford University, Stanford, CA | University of Minnesota, Minneapolis, MN | Asst. Professor, Dept. of Medicine, University of Minnesota, Minneapolis, MN	Multidimensional transcriptomic alas of recurrent uterine leiomyosarcomas uncovers stem-like hormonal cells with high drug sensitivity and improved patient outcomes 4/20/2026 9:00:00 AM | Metabolic and Transcriptional Control of Cancer Stem Cell Plasticity Open abstract	G4X
2207	Rachel B. Sidebottom, Antonia E. Sajche Sapon, Yamhilette Licon-Munoz, Christian A. Bowers, Sara G.m. Piccirillo	Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM | Neurosurgery, University of New Mexico Health Sciences Center, Albuquerque, NM	The impact of tumor treating fields (TTFields) on the transcriptome and the secretome of cancer stem-like cells isolated from the sub-ventricular zone of glioblastoma patients 4/20/2026 9:00:00 AM | Metabolic and Transcriptional Control of Cancer Stem Cell Plasticity Open abstract	-
2221	Youngtaek Kim, Gang-Taik Lee, Dong Kwon Kim, JuHyeon Lee, So Young Park, Jae Hwan Kim, Hyun Jung Yoo, Byoung Chul Cho	Yonsei University College of Medicine, Seoul, Korea, Republic of | Department of Research Support, Yonsei Biomedical Research Institute, Seoul, Korea, Republic of | Yonsei New Il Han Institute for Integrative Lung Cancer Research, Seoul, Korea, Republic of	Tumor-associated CD207+ cDC2 drives TLS formation via TNF family cytokines in non-small cell lung cancer 4/20/2026 9:00:00 AM | Tertiary Lymphoid Structures in Cancer Open abstract	Chromium
2264	Kwon Joong Na, Hongyoon Choi, Jaemoon Koh, Taeyoung Yun, Jihyeon Park, Bubse Na, Samina Park, In Kyu Park, Chang Hyun Kang, Young Tae Kim	Seoul National University Hospital, Seoul, Korea, Republic of	Spatial trajectories and niche rewiring from ground‑glass to solid transition in lung adenocarcinoma 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	Visium
2697	Rosalia Quezada Urban, Shivakumar Keerthikumar, Peter Lau, Georgia Cuffe, Linda Teng, Ashlee K. Clark, Gail P. Risbridger, Renea A. Taylor, Megan Crumbaker, ANTHONY JOSHUA, Mitchell G. Lawrence	Monash University, Clayton, Victoria, Australia | Peter MacCallum Cancer Centre, Melbourne, Australia | AGRF, Melbourne, Australia | Monash University, Melbourne, Australia | Monash University, Clayton, Australia | Garvan Institute, Sydney, Australia | St Vincents Health Australia, Melbourne, Australia	Single-cell transcriptomic characterisation reveals pathway determinants of bipolar androgen therapy response in prostate cancer 4/20/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 3 Open abstract	-
2700	Orian Stapleton, Dmitrijs Lvovs, Luciane Tsukamoto Kagohara, Elana Judith Fertig, Atul Deshpande	Johns Hopkins University, Baltimore, MD | University of Maryland School of Medicine, Baltimore, MD	SpaceMarkers 2.0: A framework for spatially aware cell-cell communication in spatial transcriptomic data 4/20/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 3 Open abstract	Visium
2708	Robert F. Gruener, Weijie Zhang, Lilin Wang, Adam M. Lee, R. Stephanie Huang	University of Minnesota, College of Pharmacy, Minneapolis, MN | University of Minnesota, Minneapolis, MN | Asst. Professor, Dept. of Medicine, University of Minnesota, Minneapolis, MN	Revealing fibroblast-mediated impacts to therapy response through spatially resolved drug response prediction in lung cancer 4/20/2026 2:00:00 PM | Integration of Clinical and Research Data Open abstract	Xenium; CosMx
2784	Thineskrishna Anbarasan, Sandy Figiel, Max Beesley, Wencheng Yin, Ruth McPherson, Richard Colling, Freddie Hamdy, Richard J. Bryant, Bartlomiej Papiez, Alastair D. Lamb, Ian Mills	University of Oxford, Oxford, United Kingdom | Barts Cancer Institute, London, United Kingdom | Oxford University Hospitals, Oxford, United Kingdom	Integrating spatial transcriptomics with MRI reveals distinct radio-spatial genomic profile concordant with prostate cancer clonal heterogeneity 4/20/2026 2:00:00 PM | Radiomics and AI in Medical Imaging Open abstract	-
2823	Junting Lu, Jinghui Xiu, Ce Zhong, Wentao Li, Wei Yun, Tan Pang, Jingqi Huang	Pharmacology, Pharmaron, Beijing, China	Single-cell RNA-seq reveals insights into the effects of immune checkpoint inhibitors 4/20/2026 2:00:00 PM | Immune Checkpoints Open abstract	Chromium
2830	Satoru Yasuda, Patrick Hall Lizotte, Elena Ivanova, Zhaorong Li, Yui Tanaka, Daisuke Okajima, Minh Ha, David A. Barbie, Cloud P. Paweletz	Daiichi Sankyo Inc, Baskin Ridge, NJ | Dana-Farber Cancer Institute, Boston, MA | Daiichi Sankyo Co. Ltd., Tokyo, Japan	Immunomodulatory response in Dato-DXd-treated non-small cell lung cancer patient-derived organotypic tumor spheroids (pDOTS) 4/20/2026 2:00:00 PM | Immune Mechanisms Invoked by Other Therapies and Exposures Open abstract	-
3104	Ramin Farhad, Di Wu, Mark A. Taylor, Allan Balmain, Rosemary J. Akhurst	Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA | Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA | Department of Anatomy, University of California, San Francisco, San Francisco, CA	Characterization of high plasticity cell states in cutaneous squamous cell carcinoma in response to chemotherapy and immune checkpoint inhibitor treatments 4/20/2026 2:00:00 PM | Overcoming Chemotherapy Resistance Open abstract	-
3326	Kazuaki Okamoto, Yalda Naeini, Anton Bilchik, Dave Hoon	Department of Translational Molecular Medicine, St. John’s Cancer Institute (SJCI), Providence St. John's Health Center (PSJHC), Santa Monica, CA | Department of Surgical Pathology, PSJHC, Santa Monica, CA | Department of Gastrointestinal and Hepatobiliary Surgery, PSJHC, Santa Monica, CA	C-myc driven by differentiation factors in early-onset colorectal cancer (EOCRC) 4/20/2026 2:00:00 PM | Tumorigenesis Drivers Open abstract	Xenium
3435	Heesoo Yoon, Jin-Wook Choi, Sejoon Lee, Jin-Haeng Chung, Hyojin Kim	Department of Pathology, Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of | Precision Medicine Center, Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of	Spatial transcriptomic profiling reveals distinct tumor microenvironment remodeling patterns associated with immune checkpoint blockade response in lung adenocarcinoma 4/20/2026 2:00:00 PM | Microenvironmental Determinants of Therapy Response and Resistance 1 Open abstract	Visium
3489	Danh Truong, Emre Arslan, Veena Kochat, Jiaqian Fan, Diana Shamsutdinova, Davis Ingram, Kevin Murgas, Clement Agyemang, Roberto Cardenas-Zuniga, Asmaa G. Ahmed, Justin Magrath, Alexander Lazar, Najat Daw Bitar, Sean B. Lee, Andrea Hayes-Dixon, Kunal Rai, Joseph A. Ludwig	UT MD Anderson Cancer Center, Houston, TX | Tulane University School of Medicine, New Orleans, LA | Howard University, Washington, DC	EWSR1::WT1 fusion oncoprotein and the androgen receptor shape the biology of desmoplastic small round cell tumors 4/20/2026 2:00:00 PM | Pediatric Cancer Genomics and Epigenomics Open abstract	-
3544	Masashi Nomura, Ramya Raviram, Joshua S. Schiffman, Lillian Bussema, Vivian Lu, Noelle Wheeler, John Lee, Yilin Fan, Mian Hua Zheng, Florian Ruiz, Husain Danish, Sorcha Kellett, Labeeba Nusrat, Ronan Chaligne, Jason T. Huse, W. K. Alfred Yung, Shota Tanaka, Nobuhito Saito, Sunit Das, Catherine Potenski, Dan Landau, Mario L. Suva	Massachusetts General Hospital, Boston, MA | Weill Cornell Medical College, New York, NY | University of Toronto, Toronto, ON, Canada | New York Genome Center, New York, NY | MD Anderson Cancer Center, Houston, TX | Okayama University, Okayama, Japan | University of Tokyo, Tokyo, Japan	Single-cell multi-omics uncovers coordinated epigenetic and transcriptomic evolution in IDH-mutant glioma 4/20/2026 2:00:00 PM | Tumor Evolution Open abstract	-
3617	Foram Ujjvalkumar Vaidya, Alvaro Gutierrez, Abberly Lott Limbach, Bhavna Kumar, Martin P. Alphonse, James W. Rocco, Mariana Brait, Amanda Ewart Toland, David Sidransky	The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD | Centro de Excelencia en Medicina Traslacional, Universidad de La Frontera, Temuco, Chile | Department of Pathology, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH | Department of Otolaryngology-Head and Neck Surgery, OSU Comprehensive Cancer Center, The Ohio State University, Columbus, OH | Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD | Department of Cancer Biology and Genetics, OSU Comprehensive Cancer Center, The Ohio State University, Columbus, OH	Immunogenomic alterations driving premalignant lesions to invasive lesions of the head and neck 4/20/2026 2:00:00 PM | Metabolism and Microbiome in Cancer Initiation and Prevention Open abstract	Visium
3722	Andrea Feci, Trevor Baybutt, Robert Carlson, Emmett Grover, Jagmohan Singh, Ross Staudt, Miao Cao, Edoardo Manca, Jasmine Alvarez, Scott A. Waldman, Adam Snook	Thomas Jefferson University, Philadelphia, PA | Chair, Dept. of Pharm. & Exp. Therapeutics, Thomas Jefferson University, Philadelphia, PA | Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, PA	Preclinical development and evaluation of CD87-directed CART for colorectal cancer 4/20/2026 2:00:00 PM | Adoptive Cell Therapy 1 Open abstract	-
3955	Hassan Brim, Khushi Desai, Shweta Dixi, Justin Hong, Colles Price, Jonathan H. Chen, Nicolas Fernandez, Sara Sim, Sami Farhi, Rabia Zafar, Elham Azizi, Hassan Ashktorab	Howard University, Dist. of Columbia, DC | Columbia, New York, NY | Takeda Pharmaceutical Company Ltd., Deerfield, IN | | Broad, New York, NY	Spatial characterization of tumor-immune interactions in MMR-p and MMR-d among African American colorectal cancer patients using attention-based modeling 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	Xenium
3957	Changjin Hong, Sunho Park, Jean R. Clemenceau, Minji Kim, Inyeop Jang, Seock-Jin Chung, Sung Hak Lee, Sam C. Wang, Tae Hyun Hwang	Section Surgical Research, Vanderbilt University Medical Center, Nashville, TN | St. Mary's Hospital Pathology, The Catholic University of Korea, Seoul, Korea, Republic of | Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX	Spatially derived transcriptomic predictors of immune checkpoint blockade outcome in advance gastric cancer 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	Visium
4036	J. Luo, S. P. Gao, J. E. Tallman, F. Kuo, M. Basar, C. Yol, S. M. Alam, H. Jiang, X. Tang, D. X. T. Zheng, J. E. Eichholz, A. Lopez Rojas, E. Turkay, J. E. Rosenberg, G. Iyer, E. J. Pietzak, D. B. Solit, H. Al-Ahmadie; Memorial Sloan Kettering Cancer Center, New York, NY		Deciphering regulatory drivers of lineage plasticity and resistance to antibody-drug conjugates in urothelial bladder cancer 4/20/2026 3:20:00 PM | Cracking Adaptive Resistance: AI-Enabled, Screen-Guided Targets in Tumor Plasticity, DNA Damage, Metabolism, and CTC-Associated Immunity Open abstract	Visium
4065	H. Yi, S. Zhang, J. Swinderman, Y. Wang, V. Kanakaveti, K. L. Hung, I. T. Wong, S. Srinivasan, E. J. Curtis, A. Bhargava-Shah, R. Li, M. G. Jones, J. Luebeck, C. Bailey, Y. Zhao, J. Belk, K. Kraft, Q. Shi, X. Yan, S. K. Pritchard, K. S. Mahajan, F. Liang, M. Jamal-Hanjani, D. W. Felsher, L. Gilbert, V. Bafna, P. S. Mischel, H. Y. Chang; Stanford University School of Medicine, Stanford, CA, Arc Institute, Palo Alto, CA, University of California at San Diego, La Jolla, CA, The Francis Crick Institute, London, United Kingdom, University College London (UCL) Cancer Institute, London, United Kingdom, Stanford Hospital, Stanford, CA, Amgen, Stanford, CA		EcDNA-borne structural variants drive oncogenic fusion transcript amplification 4/20/2026 3:55:00 PM | Oncogenic Transcriptional Control: From Chromatin to Cell Fate Open abstract	-
4244	Maryam Al-Ghezi, Malia Rettig, Christopher P. Loo, Rashi Yadav, Wesley Yu, Joshua M. Moreau	Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR | Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR | Department of Dermatology, Oregon Health & Science University, Portland, OR	Investigating the spatial immune tumor microenvironment of dermatofibrosarcoma protuberans 4/21/2026 9:00:00 AM | Adaptive Immunity in Cancer Open abstract	Visium
4788	Ryuta Watanabe, Keito Kagimoto, Mami Chosei, Tomohisa Sakaue, Mie Kurata, Noriyoshi Miura, Riko Kitazawa, Tadahiko Kikugawa, Shigeki Higashiyama, Takashi Saika	Department of Urology, Ehime University Graduate School of Medicine, Toon, Japan | Department of Biochemistry and Molecular Genetics, Ehime University Graduate School of Medicine, Toon, Japan | Department of Cardiovascular and Thoracic Surgery, Ehime University Graduate School of Medicine, Toon, Japan | Department of Analytical Pathology, Ehime University Graduate School of Medicine, Toon, Japan | Division of Diagnostic Pathology, Ehime University Hospital, Toon, Japan | Department of Oncogenesis and Growth Regulation, Osaka International Cancer Institute, Osaka, Japan	PSMA-expressing tumor vasculature in renal cell carcinoma: spatial, functional, and therapeutic implications 4/21/2026 9:00:00 AM | Angiogenesis Open abstract	Visium
4903	Yuting Shan, Lilin Wang, Matthew Jeon, R. Stephanie Huang	University of Minnesota, College of Pharmacy, Minneapolis, MN | Asst. Professor, Dept. of Medicine, University of Minnesota, Minneapolis, MN	Explore the effects of Fusobacterium nucleatum on chemotherapy response in colorectal cancer at spatial and single-cell resolution 4/21/2026 9:00:00 AM | Microbiome-Tumor-Immune Crosstalk Open abstract	Visium
4947	Xueshuai Han, Kohei Yamashita, Melissa Pool Pizzi, Kyung Serk Cho, Enyu Dai, Kai Yu, Yunhe Liu, Yibo Dai, Tian Chu, Matheus Sewastjanow-Silva, Hiro Yoshimura, Yibo Fan, Rebecca Waters, Qiong Gan, Feng Yin, Shilpa S. Dhar, Isadora Martins, Jason Willis, Mariela B. Murphy, Jenny Li, Brian D. Badgwell, Van K. Morris, Michael J. Overman, Linghua Wang, Jaffer A. Ajani	UT MD Anderson Cancer Center, Houston, TX | Gastrointestinal Medical Oncology, UT MD Anderson Cancer Center, Houston, TX	Spatially organized transcriptional programs and tumor-stroma interfaces shape immunotherapy response in microsatellite instability-high gastrointestinal cancers 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Visium
4953	Anna Mathioudaki, Zaira Seferbekova, Samuel P. Rutz, Michael Ritter, Domenico Calafato, Gleb Rukhovich, Felix Hinz, Philipp Mahlknecht, Franziska M. Ippen, Ekaterina Popova, Sophia Schinkewitsch, Nela Runa Koeberer, Nina Wilhelm, Pooja Sant, Jan-Philipp Malm, Sascha Dietrich, Christel Herold-Mende, Nima Etminan, Antje Wick, Sandro Krieg, Michael Platten, Andreas von Deimling, Felix Sahm, Abigail Suwala, Moritz Gerstung	AI in Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany | Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany | Department of Hematology, Oncology and Clinical Immunology, Medical Faculty and University Hospital Düsseldorf, Düsseldorf, Germany | Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany | Single Cell Open Lab, German Cancer Research Center (DKFZ), Heidelberg, Germany | Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany | Department of Neurosurgery, University Hospital Mannheim, Medical Faculty Mannheim (UMM), University of Heidelberg, Mannheim, Germany | Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany | Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany | Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Consortium for Translat, German Cancer Research Center (DKFZ), Heidelberg, Germany	Spatial tissue architecture as a unifying principle of tumor and microenvironmental states in adult gliomas 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4954	Jerry A. Ombor, Anurendra Kumar, Jatin Gandhi, Rakesh Shiradkar, Tilak Pathak, Cynthia L. Winham, Ismaheel O. Lawal, Olayinka A. Abiodun-Ojo, Lara Harik, Saurabh Sinha, Martin G. Sanda, David M. Schuster, Adeboye O. Osunkoya, Carlos S. Moreno	Emory University, Atlanta, GA | Georgia Institute of Technology, Atlanta, GA | Indiana University, Indianapolis, IN	Integrated scRNAseq andspatial RNAseq analysis of aggressive prostatic adenocarcinoma identifies TIGIT-NECTIN 2/3 and TIGIT/PVRimmunosuppressive interactions 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Visium
4957	Jiayi Fan, Jeffrey Quinn, Wesley Tansey	Computational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY	Spatially resolved profiling of the tumor microenvironment and therapeutic response in SMARCB1-deficient epithelioid sarcoma 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4960	Bryan Bell, Cedric Uytingco, Alec Barrett, Bryant Ngo, Jonathan Sakkos, Diksha Kool, Wanxin Wang, Melissa del Rosario, Christina Chang, Christina Fan, Andrew Farmer	Takara Bio USA, San Jose, CA	Cross-platform comparison of spatial transcriptomics technologies in an FFPE lung squamous cell carcinoma sample 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium; Visium
4962	Fan Wei, Joy C. Yang, Kenneth Iczkowski, Marc A. Dall'Era, Chengfei Liu	Department of Urologic Surgery, University of California Davis, Sacramento, CA | Department of Pathology and Laboratory Medicine, University of California Davis, Sacramento, CA	Spatial transcriptomics reveals distinct ASCL1 and ASCL2 gene expression patterns in advanced prostate cancer 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Visium
4965	Wafaa Bzeih, Yan Tang, Tiegang Han, Andrew J. Sedgewick, Nathan D. Maulding, Carmen Priolo, Katrina Collins, Hadi Mansour, Joelle Chami, Michelle M. Stein, Justin Guinney, Michel Alchoueiry, Jessica F. Williams, Michelle S. Hirsch, Pavlos Msaouel, Elizabeth P. Henske	Department of Medicine, Harvard Medical School/Brigham and Women's Hospital, Boston, MA | Tempus AI, Inc., Chigaco, IL | Indiana University School of Medicine, Indianapolis, IN | Department of Pathology, Harvard Medical School / Brigham and Women's Hospital, Boston, MA | Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX	Sarcomatoid transformation rewires the immune spatial landscape and checkpoint regulation in chromophobe renal cell carcinoma 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium
4995	Yulong Wei, David Alexander Braun, Ya-Chi Ho	Microbial Pathogenesis, Yale School of Medicine, New Haven, CT | Medical Oncology and Hematology, Yale School of Medicine, New Haven, CT	LAMP3+ migratory dendritic cells establish immune-accessible tumor microenvironment in non-Hodgkin lymphoma 4/21/2026 9:00:00 AM | Tumor-Immune Crosstalk Open abstract	Xenium
5248	Shuang Zhao, Yanjing Tang, Meng Su, Bowen Cui, Rongrong Fan, Han Wang, Liu Yang, Lixia Ding, Ronghua Wang, Huiying Sun, Ying Zhong, Qiaoqiao Shi, Yuxuan Guo, Lili Song, Xinyu Wan, Tianyi Wang, Jing Yang, Benshang Li, Yu Liu	Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, shanghai, China | National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, shanghai, China	Single-cell multi-omics reveals co-mutation of TP53 and epigenetic gene driving myeloid transformation in B-ALL following CAR-T therapy 4/21/2026 9:00:00 AM | Biomarkers Predictive of Therapeutic Benefit 5 Open abstract	-
5265	Yanxia Ma, Nhat Nguyen, Xuehong Gui, Edgardo Aguilar, Luke Connell, Denae Neill, Emil Schüler, Chibawanye I. Ene	Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX	FLASH radiotherapy improves survival in mouse glioblastoma and spares circulating antigen reactive CD8+T-cells 4/21/2026 9:00:00 AM | Effects of Ionizing Radiation on Normal Tissues and FLASH Radiation Research Open abstract	Xenium
5514	Jingyi Wang, Hongpan Zhang, Zhenjia Wang, Chongzhi Zang	Department of Genome Sciences, University of Virginia, Charlottesville, VA | Department of Genome Sciences, University of Virginia, CHARLOTTESVILLE, VA	BART-spatial: Predicting biologically significant transcriptional regulators from spatial omics data 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Visium
5519	Junming Shi, Md Tauhidul Islam	Stanford University School of Medicine, Stanford, CA	SOMaC: An interpretable and generalizable framework for integrating and clustering multimodal spatial omics to resolve cell states and immune niches in cancer 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; Visium
5524	Mary Goldman, Brian Craft, Cally Lin, Jingchun Zhu, David Haussler	UC Santa Cruz Genomics Institute, Santa Cruz, CA | Stanford University, San Francisco, CA | Investigator/Distinguished Professor, Ctr. For Bio. Sci. & Eng., UC Santa Cruz, Santa Cruz, CA	Visualization and analysis of cancer genomics data using UCSC Xena 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; Visium; Chromium; CosMx; MerFISH
5550	Umair Munawar, Alexander Leipold, Seungbin Han, Silvia Nerreter, Shilpa Kurian, Emma Besant, Nina Rein, Johanna Lehmann, Max Koeppel, Xiang Zhou, Ondrej Slaby, Hermann Einsele, Leo Rasche, Emmanual Saliba, Johannes Waldschmidt, Martin Kortuem	University Hospital Wuerzburg, Wuerzburg, Germany | Helmholtz Institute for RNA-based Infection Research, Wuerzburg, Germany | Masaryk University, Brno, Czech Republic	T cell transcriptome is altered by Talquetamab in presence of GPRC5D on MM cells 4/21/2026 2:00:00 PM | Bi- and Tri-Specific Antibody Therapies Open abstract	-
5554	Soojin Ryu, Hee Geon Park, Sang Beom Bang, Ji Hye Nam, Ho Jin Lee, Ju Yeon Seo, Gun Yi Ahn, Myeung Ryun Seo, Sang Moo Lee, Yoon La Choi, Sung Youl Hong, Young Kee Shin	Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Korea, Republic of | Logone Bio-Convergence Research Foundation, Seoul, Korea, Republic of | SNU Future Innovation Institute, Seoul National University, Seoul, Korea, Republic of | Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of | BitD Inc., Siheung, Korea, Republic of	Anti-human CTLA-4×TIGIT bispecific antibody: A novel immunotherapy specifically targeting tumor-infiltrating FOXP3+ regulatory T cells 4/21/2026 2:00:00 PM | Bi- and Tri-Specific Antibody Therapies Open abstract	-
5620	Kayla J. Bendinelli, Allison M. Kirk, Marina Baretti, Abigail M. Gottschall, Heng-Chung Kung, Jeric Peter Hernandez, Waqar Arif, Julie Nauroth, Jennifer Durham, Christopher Thoburn, Amanda Huff, Neeha Zaidi, Alexei Hernandez, Hassan Jamaleddine, Timothy N. West, Justin McCallen, George Coukos, Alexandre Harari, Challice L. Bonifant, Elizabeth Jaffee, Won Jin Ho, Grégoire Altan-Bonnet, Paul G. Thomas, Mark Yarchoan	Johns Hopkins University School of Medicine, Baltimore, MD | Department of Host-Microbe Interactions, St. Jude Children’s Research Hospital, Memphis, TN | Johns Hopkins University, Baltimore, MD | JOHNS HOPKINS UNIVERSITY, Baltimore, MD | Oncology, Johns Hopkins Hospital, Baltimore, MD | National Cancer Institute, Bethesda, MD | UNIL University of Lausanne, Lausanne, Switzerland | Harari (Individual), Lausanne, Switzerland | Fred Hutchinson Cancer Center, Seattle, WA | Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD	Development of T cell receptor (TCR) based cellular therapy for fibrolamellar HCC uncovers role of TCR in CD4 T cell differentiation 4/21/2026 2:00:00 PM | TCR and Autologous T Cell Therapies Open abstract	-
5843	Laura Doherty, Ashish B. George, Mustafa Kocak, Paul Lund, Andrew Kohlway, Andrew Boddicker, Ben Song, Carlos Ruiz Perez, Bryan Lajoie, Catarina D. Campbell, Matthew G. Rees, Jennifer A. Roth	Broad Institute of MIT and Harvard, Cambridge, MA | 10x Genomics, Pleasanton, CA | Element Biosciences, San Diego, CA	Beyond viability: Post treatment single cell and spatial transcriptomic profiling in mixtures of PRISM barcoded cancer cell lines 4/21/2026 2:00:00 PM | Tumor Microenvironment, Multispecifics, and Immunomodulation Open abstract	-
5921	Preety Bajwa, Carly Chapman, Dylan Glubb, Tracy O'Mara	QIMR Berghofer Medical Research Institute, Brisbane, Australia	Cell type-specific mapping of endometrial cancer risk genes using single-nucleus multi-omics 4/21/2026 2:00:00 PM | Genetic and Transcriptomic Dissection of Cancer Evolution Open abstract	-
5922	Yujin Lee, Moray J. Campbell, James C. Fleet	Dept. of Nutritional Sciences, The University of Texas at Austin, Austin, TX | Karmanos Cancer Institute, Wayne State University, Detroit, MI	Single-cell mapping of the colon epithelium reveals a pre-malignant stem cell that defines early transformation risk 4/21/2026 2:00:00 PM | Genetic and Transcriptomic Dissection of Cancer Evolution Open abstract	Chromium
5930	Haruki Sada, Hiroaki Niitsu, Hikaru Nakahara, Masashi Miguchi, Hirotaka Tashiro, Hideki Ohdan, Takao Hinoi	Surgery, NHO Kure medical center, Kure, Japan | Clinical and Molecular Genetics, Hiroshima University Hospital, Hiroshima, Japan | Department of Gastroenterological Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan | Gastroenterological and Transplant Surgery, Hiroshima University,, Hiroshima, Japan	Spatial transcriptomics of colonic neoplasia presenting mucinous adenocarcinoma with genetically-engineered mouse model 4/21/2026 2:00:00 PM | Genetic and Transcriptomic Dissection of Cancer Evolution Open abstract	-
5938	Gonzalo Lopez Garcia, Felix Andreas Radtke, Sagnik Banerjee, BIJAY JAISWAL, Daiane Hemerich Brennan, Yilin Zhao, Verena Körber, Marlen Metzner, Rachel Moore, Bilyana Stoilova, Junfei Zhao, Bettina Nadorp, David Cruz Hernandez, Batchimeg Usukhbayar, Aimee O’Donohue, Maria Ortiz Estevez, Daniel Lopes de Menezes, Rajasekhar NVS Suragani, Paresh Vyas, Anita Gandhi	Informatics and Predictive Sciences, Bristol Myers Squibb, Cambridge, MA | Weatherall Institute for Molecular Medicine, Headington | Informatics and Predictive Sciences, Bristol Myers Squibb, San Diego, CA | Translational Development, Bristol Myers Squibb, Brisbane, CA | Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, NJ | Informatics and Predictive Sciences, Bristol Myers Squibb, Seattle, WA | University of Oxford, Oxford, United Kingdom | Translational Development, Bristol Myers Squibb, Summit, NJ | Informatics and Predictive Sciences, Bristol Myers Squibb, Sevilla, Spain | Translational Development, Bristol Myers Squibb, Cambridge, MA | University of Oxford, Department of Biochemistry, Oxford, United Kingdom	High-resolution multi-omic dissection of bone marrow in TP53-mutant acute myeloid leukemia 4/21/2026 2:00:00 PM | Genetic and Transcriptomic Dissection of Cancer Evolution Open abstract	-
5946	Adi Caspi, Ariana A. Entezari, Jasmine R. Alvarez, Annie K. Londregan, Thomas J. M. Kuret, Jeffrey A. Rappaport, Adam E. Snook, Scott A. Waldman	Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA | Department of Medicine, Johns Hopkins University, Baltimore, MD	Proteomics at the guanylin gene locus reveals Wnt/β-catenin regulatory factors underlying GUCY2C hormone silencing in colorectal cancer 4/21/2026 2:00:00 PM | Mechanisms and Dynamics of Gene Expression Open abstract	-
6118	Junghan Oh, Hoyeon Jeong, Yoon La Choi, Donggun Lee, Misook Lee	Samsung Advanced Institute of Technology, Seoul, Korea, Republic of | Samsung Advanced Institute for Health Sciences and Technology, Seoul, Korea, Republic of	Spatially resolved SEED (stromal-enriched metastatic decider) niches integrate tumor, stromal, and immune ecosystems to enable lymph node dissemination in LUAD 4/21/2026 2:00:00 PM | Metastasis and Organ-Specific Microenvironmental Evolution Open abstract	Xenium
6158	Tadahito Yasuda, Mayu Yasuda, Atsuko Yonemura, Fabio de Mello, Feng Guo, Boping Jing, Hudie Li, Takatsugu Ishimoto, Yaoqi Alan Wang	Indiana University School of Medicine, Indianapolis, IN | The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan	Senescent tumor-associated macrophages promote peritoneal metastatic niche formation in gastric cancer 4/21/2026 2:00:00 PM | Metastatic Niches and Microenvironment Open abstract	Visium
6159	Ping Xu, Yuehui Zhao, Yun Yan, Rui Ye, Chenling Tang, Emi Sei, Shanshan Bai, Tuan Tran, Cole Ruoff, Christine Ly, Keyi Zhu, Miao Zhang, Bila A. Siddiqui, Sumit K. Subudhi, Paul Corn, Christopher J. Logothetis, Patricia Troncoso, Amado J. Zurita-Saavedra, Nicholas Navin	Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX | Department of Pathology, UT MD Anderson Cancer Center, Houston, TX | Department of Genitourinary Medical Oncology, UT MD Anderson Cancer Center, Houston, TX	Co-evolution of cancer cells and their microenvironment of primary and lymph node metastatic prostate cancer under androgen deprivation therapy 4/21/2026 2:00:00 PM | Metastatic Niches and Microenvironment Open abstract	Xenium; Visium
6187	Yajas Shah, Tianyou Luo, Christine M. Hoeman, Luca Lonini, Stanislaw Szydlo, Eduardo Diaz, Rossin Erbe, Matthew B. Maxwell, Michelle M. Stein, Andrew J. Sedgewick, Nicholas Rachell, Zachary Chelsky, Sonal Khare, Ryan D. Jones, Kate Sasser, Richard A. Klinghoffer, Justin Guinney, Chi-Sing Ho	Tempus AI, Chicago, IL	Elevating bulk sequencing with high-resolution spatial transcriptomics: A paired-data analysis of clinically-relevant spatial niches in CRC and NSCLC 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Visium
6189	Nora M. Lawson, Inés Martín-Barrio, Lingqun Ye, Bo Zhao, Thomas Mitchell, Mesut Unal, Chae Yun Cho, Andrew Futreal, Kadir C. Akdemir	Neurosurgery, UT MD Anderson Cancer Center, Houston, TX | Genetics, UT MD Anderson Cancer Center, Houston, TX | Genomic Medicine, UT MD Anderson Cancer Center, Houston, TX	ERBB2 expression and the immune landscape shape the tumor microenvironment and influence prognosis in esophageal adenocarcinoma brain metastases 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium
6195	Heng Luo, Clémence Henon, Gleb Rukhovich, Stefanie Kutschmann, Nina Wilhelm, Wolfgang Hartmann, Uta Dirksen, Duncan T. Odom, Thomas G. Grünewald, Moritz Gerstung	Division of Artificial Intelligence in Oncology, DKFZ German Cancer Research Center, Heidelberg, Germany | Division of Translational Pediatric Sarcoma Research, DKFZ German Cancer Research Center, Heidelberg, Germany | Gerhard-Domagk-Institute of Pathology, Münster University Hospital, Muenster, Germany | Pediatrics III, University Hospital Essen, West German Cancer Center, NCT West, Essen, Germany | Division of Regulatory Genomics and Cancer Evolution, DKFZ German Cancer Research Center, Heidelberg, Germany	Spatial transcriptomics analysis reveals tumor cell plasticity and diverse tumor microenvironments in Ewing sarcoma 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium
6204	Ryuta Watanabe, Kensuke Shishido, Shota Nobumori, Naoya Sugihara, Keigo Nishida, Haruna Arai, Takatora Sawada, Shunsuke Haga, Osuke Arai, Tomoya Onishi, Kenichi Nishimura, Tstsuya Fukumoto, Noriyoshi Miura, Mie Kurara, Riko Kitazawa, Yuki Miyauchi, Tadahiko Kikugawa, Takashi Saika	Department of Urology, Ehime University Graduate School of Medicine, Toon, Japan | Department of Analytical Pathology, Ehime University Graduate School of Medicine, Toon, Japan | Division of Diagnostic Pathology, Ehime University Hospital, Toon, Japan	Spatial transcriptomic dissection of TSC-associated angiomyolipoma reveals microenvironmental programs driven by mTORC1 dysregulation 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Visium
6205	Tommy Tran, JingHao Tian, Elim Cheung, Rikita Gakhar, Vidyodhaya Sundaram	BioChain Institute, Inc., Newark, CA	Establishing reproducibility standards for Xenium spatial transcriptomics through multi-replicate validation and cross-sectional analysis 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Xenium
6211	Samuel Mwakisha Mwamburi, Jevon Layne, Niki Talebian, Ezra G. Baraban, Ashley Kiemen, Clayton C. Yates	Pathology, Johns Hopkins University School of Medicine, Baltimore, MD	AI-guided spatial multi-omics integration reveals immune and stromal heterogeneity underlying population disparities in prostate cancer. 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Visium
6214	Gaurav N. Joshi, Nicholas Sciascia, Michael Yang, Brenna Fearey, Junya Yoshioka, Fumiki Yanagawa	Nikon Bioimaging Lab, Nikon Instruments Inc, Lexington, MA	Mapping the tumor landscape: spatial multiomics reveals immune and stromal heterogeneity across early and late-stage NSCLC 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	Visium
6216	Amanda Janesick, McKenzi Toh, Syrus Mohabbat, Stephanie Kravitz, 10X Genomics Development Team	10x Genomics, Inc., Pleasanton, CA	Novel whole transcriptome spatial transcriptomics technology reveals CAF/TAM-mediated basement membrane remodeling at the invasive front 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	-
6447	Serena Zheng, Jason Link, Alykhan Premji, Michael Srienc, McKensie Hammons, Shineui Kim, David Dawson, Zev Wainberg, Timothy Donahue	Surgery, UCLA Medical Center, Los Angeles, CA | UCLA David Geffen School of Medicine, Los Angeles, CA | Pathology, UCLA Medical Center, Los Angeles, CA | Medicine, UCLA Medical Center, Los Angeles, CA	FOLFIRINOX plus nivolumab promotes plasma cell production from intra-tumoral lymphoid aggregates in borderline resectable pancreatic adenocarcinoma 4/21/2026 2:00:00 PM | Biostatistics in Clinical Trials / Surgical Oncology Open abstract	Xenium
6455	Naoki Mizutani, Shloka Shukla, Nicholas Fidelman, Bridget P. Keenan, David Y. Oh, Kira Chan, Li Zhang, Emily K. Bergsland, Thomas Hope, Lawrence Fong	Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA | University of California San Francisco, San Francisco, CA	Cytotoxic T-cell signatures underlie therapeutic response to 177Lu-DOTATATE plus pembrolizumab in well-differentiated gastroenteric neuroendocrine tumors 4/21/2026 2:00:00 PM | Clinical Correlates of Immunotherapy Open abstract	-
6463	Yiyun Chen, Kun-Wei Song, Moksha H. Desai, Ying-Wen Huang, Nadya Iswari, Zachary J. Ehlinger, Hossein Daghagh, Maximilian R. A. Koch, Kevin Reynolds, Kelvin C. Mo, Kristin C. Y. Tsui, Skyler Rietberg, Mark P. Hamilton, Snehit Prabhu, Sonia Partap, Jasia Mahdi, Emily Egeler, Steven A. Feldman, Sabine Heitzeneder, Sean A. Yamada-Hunter, Elena Sotillo, Bita Sahaf, Zinaida Good, Michelle Monje, Sneha Ramakrishna, Crystal L. Mackall	Stanford Cancer Institute, Stanford, CA	Longitudinal single-cell atlas of GD2-CAR T cell therapy in H3K27M-mutant diffuse midline glioma identifies humoral and cellular anti-CAR immunity 4/21/2026 2:00:00 PM | Clinical Correlates of Immunotherapy Open abstract	-
6573	Paula O. Cooper, Laila N. Scroggins, Sally Elsamanoudi, Amina Ali, Picabo Binette, Beatriz German Falcon, Leigh Ellis, Gregory T. Chesnut, Shyh-Han Tan, Cara C. Schafer	Surgery, Center for Prostate Disease Research, Bethesda, MD	Assessment of the T cell receptor repertoire in racially diverse prostate cancer patients 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	Xenium
6576	Chih-Hung Chung, Han-Hsun Yu, Muh-Hwa Yang	National Yang Ming Chiao Tung University, Taipei, Taiwan	Integrative spatial transcriptomics reveals EMT-driven immune regulatory programs underlying metastasis in HNSCC 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	Xenium; Visium; GeoMx
6660	Daniel Jimenez-Sanchez, Brian J. Lane, Matthew H. Ingalls, Charles Eldon Jackson, Steven T. Lott, Adam Northcutt, Arne Christians, Anke Brix, Jennifer Brooks, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO | Bruker Spatial Biology, Hanover, Germany	CellScape Quality Control (CSQC): A tissue- and protein-agnostic platform for spatial proteomics quality assessment 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	CellScape
6662	Maryam Ranjpour, Mohamed Omar	Cedars-Sinai Medical Center, Los Angeles, CA	Spatial genomics reveals microenvironmental programs associated with organ-specific metastatic propensity in prostate cancer 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	Xenium
6681	Hiroshi M. Sasaki, Seayar H. Mohabbet, Ian T. Fiddes, Francesca Meschi, 10x Genomics Development Team	Spatial Biology, 10x Genomics, Inc., Pleasanton, CA | Histopathology Core, 10x Genomics, Inc., Pleasanton, CA | Computational Biology, 10x Genomics, Inc., Pleasanton, CA	Innovative 10x Genomics technologies enable clinical-scale cancer research and AI-driven biomarker discovery 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	-
6718	Abraham A. Hakim, Lisa Kenney, Nivedita Mohan Ratnam, Jared J. Gartner, Ian S. Goldlust, Aarushi Bhasin, Brian Bui, Nicholas D. Klemen, Steven A. Rosenberg, Frank J. Lowery	NIH-NCI, Bethesda, MD | Laboratory of Integrative Cancer Immunology (LICI), Center for Cancer Research, Bethesda, MD | National Cancer Institute, Bethesda, MD | National Institutes for Health, Bethesda, MD | Surgery Branch, NIH-NCI, Bethesda, MD | Surgery Branch, National Cancer Institute, Bethesda, MD	Identifying new cell surface markers of T-cell reactivity through single cell transcriptomic analysis 4/21/2026 2:00:00 PM | Vaccines and Other Immunomodulatory Agents Open abstract	Chromium
6740	S. Punekar, A. J. Schoenfeld, E. B. Garon, S. Y. Kim, K. He, J. Marks, B. S. Henick, S. V. Liu, N. Seetharamu, A. Spira, J. Gainor, T. Larson, T. A. Leal, C. Oswalt, B. Izar, A. Marangoz-Stager, V. Danh, G. Lunardi, K. Bach, N. A. Rizvi, A. Azrilevich, A. Mehta-Damani, M. Oft; NYU, New York, NY, Memorial Sloan Kettering Cancer Center, New York, NY, University of California (UCLA), Santa Monica, CA, Yale, New Haven, CT, The Ohio State University Wexner Medical Ctr., Columbus, OH, DFCI, Boston, MA, Columbia University, New York, NY, Georgetown University, Washington, DC, Northwell Health, Great Neck, NY, Virginia Cancer Specialists, Fairfax, VA, Mass General Hospital, Boston, MA, HealthPartners, Minneapolis, MN, Emory University, Atlanta, GA, Duke University, Durham, NC, Columbia University Irving Medical Center, New York, NY, Synthekine, Menlo Park, CA		Selective immune activation of antigen activated T cells with STK-012, an a/b IL-2 receptor biased partial agonist, with pembrolizumab and chemotherapy in 1L PD-L1 negative non-squamous NSCLC 4/21/2026 2:35:00 PM | Immunotherapy: Mechanisms and Responses Open abstract	-
6759	P. Kerwin, L. Zanella, A. Califano; Columbia University, New York, NY		High-throughput drug screening and single-cell network analysis identify rational combination therapies in IDH-mutant glioma 4/21/2026 2:50:00 PM | Targeted Therapy: Data Driven Approaches and Novel Drugs Open abstract	Xenium
6796	Y. Wang, J. Chen, O. Cope, A. Mehta, D. Fleifel, C. Gutierrez-Ford, P. Behnamie, S. Haase, S. Gulec, T. C. Elston, P. M. Spanheimer, C. Tomblin, A. Rojas, T. Tate, J. E. Purvis, J. Wang, J. M. Dahl, S. Wolff, J. Cook, E. C. Brunk; University of North Carolina at Chapel Hill, Chapel Hill, NC, UNC School of Medicine, Chapel Hill, NC, Bioskryb Genomics, Durham, NC, UNC School of Medicine, NC		AI enabled imaging and single cell multiomics reveal how gene amplification architecture shapes gene expression 4/21/2026 3:20:00 PM | Genomic Approaches to Understanding Tumor Evolution Open abstract	-
6797	M. Wang, A. Sabet, S. Rakhade, E. Spanos, L. Morrill Gavarró, R. Giri, P. Manoj, H. A. Yu, A. Quintanal-Villalonga, J. T. Poirier, E. Redin, D. Pe'er, C. M. Rudin, J. M. Chan; Memorial Sloan Kettering Cancer Center, New York, NY, Herbert Irving Comprehensive Cancer Ctr., New York, NY, NYU Langone Health Perlmutter Cancer Ctr., Brooklyn, NY		Basal-state origins and genotype-specific trajectories of neuroendocrine plasticity in lung cancer 4/21/2026 3:35:00 PM | Genomic Approaches to Understanding Tumor Evolution Open abstract	Xenium
6877	Lucio R. Queiroz, Shreyas Rajaram, Karnika Singh, Angelo Corso Faini, Erika Minonne, Nicola Barbaro, Scarfó Federico, Pushpita Roy, Wikum Dinalankara, Luigi Marchionni	Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY | Università di Torino, Torino, Italy | Università San Raffaele, Milano, Italy	Chromatin networks inform the development of prognostic gene expression signatures in human cancers 4/22/2026 9:00:00 AM | Network Biology and Precision Medicine Open abstract	-
6895	Yufeng He, Yanping Zhao, Rui Zhang, Heli Yang, Zhaode Bu, Yuan Luo, Deng Pan, Zexian Zeng	Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China | Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China | Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Peking University, Beijing, China | Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL | Tsinghua-Peking Center for Life Sciences, Department of Basic Medical Sciences, Tsinghua University, Beijing, China	DISSECT integrates cytological images and spatial transcriptomics for cell segmentation 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	Xenium; Visium; CosMx
6982	Alexander Lim, Wei Tian, Zhuoning Li, Mara Monetti, Alexander Noor Shoushtari, James Smithy, Samuel Tischfield, Mark Donoghue, David A. Scheinberg, Chenyang Zhan	Memorial Sloan Kettering Cancer Center, New York, NY	Patient-derived uveal melanoma organoids reveal HLA-I-restricted tumor antigens and tumor-reactive T cells 4/22/2026 9:00:00 AM | Novel Models of Immunotherapy Response Open abstract	-
7012	Qianyun Luo, Rebecca LaRue, Enoc Granados Centeno, Kyra Bergerud, Michael Farrar, Sean Tracy	University of Minnesota, Minneapolis, MN	Single-cell multi-omics identifies MRD-associated Tr1-like CD4 cells in B-ALL 4/22/2026 9:00:00 AM | Tumor-induced Immune Suppression Open abstract	Chromium
7027	Benjamin B. Morris, Monique B. Nilsson, Ethan Earlie, Eric E. Gardner, Hong Chen, Santiago G. Trevino, Alexa J. Halliday, Yuanxin Xi, Jing Wang, Natalie Vokes, Don Gibbons, Jianjun Zhang, Ashley M. Laughney, Yasir Y. Elamin, Xiuning Le, John V. Heymach	Thoracic/Head and Neck Medical Oncology, UT MD Anderson Cancer Center, Houston, TX | Department of Systems and Computational Biomedicine, Weill Cornell Medicine, New York, NY | Weill Cornell Medicine, New York, NY | UT MD Anderson Cancer Center, Houston, TX	Multi-lineage evolution of drug resistance via a novel keratin 17+ drug tolerant persister population in EGFR-mutant NSCLC 4/22/2026 9:00:00 AM | Drug Resistance 2: Tyrosine Kinase Inhibitors Open abstract	-
7399	Haley du Bois, Alberto Chaves, Ryan Bishop, Dina Atta, Jeremy Steven Frieling, Karl Nyman, Tao Li, Mostafa Nasr, Conor C. Lynch	Moffitt Cancer Center, Tampa, FL | College of Engineering, University of South Florida, Tampa, FL | H. Lee Moffitt Cancer Center and Research Institute and the University of South Florida, Tampa, FL | Tumor Microenvironment & Metastasis, Moffitt Cancer Center, Tampa, FL	Eosinophils promote an immunosuppressive bone marrow microenvironment in multiple myeloma 4/22/2026 9:00:00 AM | Functional and Spatial Regulation of Immune Evasion and Anti-Tumor Immunity Open abstract	Visium
7412	Minyeop Kim, Youwon Lee, Seung Yeon Oh, Eun Ji Lee, Ji Ae Ko, Jihyoung Mun, Byoung Chul Cho, Mi Ran Yun	Yonsei University College of Medicine, Seoul, Korea, Republic of | Yonsei University College of Medicine SBSI, Seoul, Korea, Republic of	ANXA1 and MYADM regulate CD4+T cell differentiation and exhaustion in non-small cell lung cancer (NSCLC) 4/22/2026 9:00:00 AM | Functional and Spatial Regulation of Immune Evasion and Anti-Tumor Immunity Open abstract	-
7436	Kathryn H. Gessner, Jeffrey S. Damrauer, Siyao Liu, Mi Zhou, David Corcoran, Sara E. Wobker, William Kim	UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC	Dissecting the spatial architecture of plasmacytoid urothelial carcinoma to inform therapeutic strategies 4/22/2026 9:00:00 AM | Microenvironmental Determinants of Therapy Response and Resistance 2 Open abstract	Xenium
7451	Jaber H. Jaradat, Zaid Alwarawrah, Laith Alomari, Anwaar Saeed, Azhar Saeed	Faculty of Medicine, Mutah University, Al-Karak, Jordan | Griffin Hospital, Derby, CT | Department of Medicine, Jefferson Einstein Philadelphia Hospital, Philadelphia, PA | UPMC Hillman Cancer Center, Pittsburgh, PA | University of Vermont Medical Center, Colchester, VT	Integrated bulk and single cell transcriptomics reveal PARL as a mitochondrial regulator associated with immunometabolic reprogramming and favorable prognosis in lung squamous cell carcinoma 4/22/2026 9:00:00 AM | Therapeutic Modulation of the Tumor Microenvironment: New Targets and Approaches 2 Open abstract	-
7500	Felix A. Radtke, Bijay S. Jaiswal, Gonzalo Lopez, Junfei Zhao, Sagnik Banerjee, Daiane Hemerich Brennan, Yilin Zhao, Verena Körber, Marlen Metzner, Rachel Moore, Bilyana Stoilova, Batchimeg Usukhbayar, David Cruz Hernandez, Maria Ortiz Estevez, Aimee O’Donohue, Daniel Lopes de Menezes, Rajasekhar NVS Suragani, Anita K. Gandhi, Paresh Vyas	MRC Molecular Haematology Unit, Radcliffe Department of Medicine, Weatherall Institute of Medicine, University of Oxford, Oxford, United Kingdom | Translational Development, Bristol Myers Squibb, Brisbane, CA | Informatics and Predictive Sciences, Bristol Myers Squibb, Cambridge, MA | Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, NJ | Informatics and Predictive Sciences, Bristol Myers Squibb, San Diego, CA | Informatics and Predictive Sciences, Bristol Myers Squibb, Seattle, WA | Informatics and Predictive Sciences, Bristol Myers Squibb, Sevilla, Spain | Translational Development, Bristol Myers Squibb, Summit, NJ | Translational Development, Bristol Myers Squibb, Cambridge, MA	Dependent lineage regulatory programs in TP53-mutated acute myeloid leukemia revealed through deep single-cell multi-omic profiling of patient samples 4/22/2026 9:00:00 AM | Tumor Heterogeneity Open abstract	-
7732	Maria F. Mercogliano, Nadine Schrode, Kristin Beaumont, Roxana Schillaci	Laboratorio de Inmunología Tumoral, Instituto de Biología y Medicina Experimental, Buenos Aires, Argentina | Center for Advanced Genomics Technology, Icahn School of Medicine at Mount Sinai, New York, NY | Icahn School of Medicine at Mount Sinai, New York, NY | Laboratorio de Inmunología Tumoral, Instituto de Biología y Medicina Experimental, Buenos Aires, Argentina	A stromal-immune spatial transcriptomic signature associated with MUC4 identifies potential biomarkers of trastuzumab resistance in HER2-positive breast cancer 4/22/2026 9:00:00 AM | Biomarkers Predictive of Therapeutic Benefit 6 Open abstract	Visium
7751	Zihui Zhao, Xiaohang Long, Siyuan HUANG, Yan Liu, Alfred S. l. Cheng	School of Biomedical Science, Chinese University of Hong Kong (CUHK), Hong Kong, Hong Kong | CUHK, NT, Hong Kong | The Chinese University of Hong Kong, Shatin, NT | Chinese University of Hong Kong (CUHK), Hong Kong, Hong Kong	Integrative multi-omics and spatial transcriptomics reveal novel immunotherapy targets in hepatocellular carcinoma 4/22/2026 9:00:00 AM | Immune Response to Therapies Open abstract	-
7767	Sophia A. Paxton, Corinne H. Strawser, Lakshmi Prakruthi Rao Venkata, Elizabeth A. R. Garfinkle, James M. Markert, Katherine E. Miller, Kevin A. Cassady, Elaine R. Mardis	The Steve and Cindy Rasmussen Institute for Genomic Medicine, The Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH | Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL | Center for Childhood Cancer Research, The Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH	Spatial profiling of the tumor immune microenvironment following oncolytic herpes simplex virus treatment in glioblastoma 4/22/2026 9:00:00 AM | Immune Response to Therapies Open abstract	Visium
	Andrew Shaver. 10x Genomics, Pleasanton, NJ		Witness the impossible with 10x genomics 4/19/2026 1:30:00 PM | Witness the Impossible with 10x Genomics Open abstract	-
LB122	Grégoire Marret, Jinsu An, Farnoosh Abbas Aghababazadeh, Kewei Ni, Lucas Penny, Martin Hyrcza, Ben X. Wang, Enrique Sanz-Garcia, Anna Spreafico, Giselle Boukhaled, Simone Stone, Aaron R. Hansen, Troy Ketela, Benjamin Haibe-Kains, Scott V. Bratman, Pinaki Bose, Lillian L. Siu	Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, Canada | Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada | Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, Canada | Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada | Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada	Dynamic interactions of spatially organized tumor, stromal and immune cellular niches predict outcome to immune checkpoint blockade (ICB) in recurrent or metastatic head and neck squamous cell carcinoma (RM-HNSCC) 4/20/2026 9:00:00 AM | Late-Breaking Research: Clinical Research 2 Open abstract	Visium
LB123	Anna Vila-Escoda, Marta Piqué-Gili, Marta Casado-Pelaez, Roser Pinyol, Ana Hernández de Sande, Verónica Davalos, Albert Gris-Oliver, Carla Montironi, Judit Peix, Daniela Grases, Ezequiel Mauro, Guillem Cano-Segarra, Sarah Cappuyns, Igor Figueiredo, Giorgio Ioannou, Edgar Gonzalez-Kozlova, Tim Meyer, Anja Lachenmayer, Jens U Marquardt, Helen L Reeves, Julien Edeline, Fabian Finkelmeier, Jörg Trojan, Sacha Gnjatic, Jean-Frederic Blanc, Richard A Hubner, Matthias Pinter, Tom Luedde, Arndt Vogel, Daniela Sia, Vincenzo Mazzaferro, Manel Esteller, Jeroen Dekervel, Eduard Porta-Pardo, Josep M Llovet	Liver Cancer Translational Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona. Mount Sinai Liver Cancer Program, Divisions of Liver Diseases, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY | Cancer Epigenetics Group, Josep Carreras Leukaemia Research Institute (IJC), IJC Building, Germans Trias I Pujol, Barcelona, Spain | Liver Cancer Translational Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona, Spain | Liver Cancer Translational Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic; Pathology Department and Molecular Biology Core, Hospital Clínic of Barcelona, Barcelona, Spain | Josep Carreras Leukemia Research Institute (IJC), Barcelona, Spain | Liver Cancer Translational Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Barcelona, Spain | Digestive Oncology, Department of Gastroenterology, University Hospitals Leuven, Leuven, Belgium | Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY | Research Department of Oncology, UCL Cancer Institute, University College London, Royal Free Hospital, London, United Kingdom | Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland | Department of Medicine I, University Medical Center Schleswig Holstein Campus Lübeck, Lübeck, Germany | Newcastle University Translational Research Institute, Newcastle upon Tyne NHS Foundation Trust, and NIHR Newcastle Biomedical Research Centre, Newcastle, United Kingdom | Department of Medical Oncology, Centre Eugène Marquis, Rennes, France | Department of Gastroenterology, University Liver and Cancer Centre, Frankfurt, Germany | Department of Hepatogastroenterology and Medical Oncology, CHU de Bordeaux Hôpital Haut-Lévêque, Pessac, France | Department of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester, United Kingdom | Division of Gastroenterology and Hepatology, Department of Medicine, Medical University of Vienna, Vienna, Austria | Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Dusseldorf, Medical Faculty at Heinrich Heine University Dusseldorf, Dusseldorf, Germany | Hannover Medical School, Hannover, Austria | Mount Sinai Liver Cancer Program, Divisions of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY | Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy; HPB Surgery, Hepatology and Liver Transplantation, Fondazione IRCCS Istituto Nazionale Tumori di Milano, Milan, Italy | Josep Carreras Leukemia Research Institute (IJC).Centro de Investigacion Biomedica en Red Cancer. Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain | Department of Gastroenterology and Hepatology, University Hospitals KU Leuven, Leuven, Belgium | Josep Carreras Leukemia Research Institute (IJC). Barcelona Supercomputing Center (BSC), Barcelona, Spain	Spatial immune architecture at single-cell resolution predicts response to atezolizumab plus bevacizumab in advanced HCC 4/20/2026 9:00:00 AM | Late-Breaking Research: Clinical Research 2 Open abstract	Xenium
LB163	Dor Simkin, Thomas F. Barrett, Lingling Zhang, Michael J. Moore, Alissa R. Greenwald, Noam G. Darnell, Michael Mints, Salma Ramadan, Victoria Yu, Riley DZ Mullins, Jesse Zaretsky, Porter Bischoff, Douglas Adkins, Wade L. Thorstad, Sana D. Karam, Randall C. Paniello, Jason T. Rich, Ryan S. Jackson, Patrik Pipkorn, Paul A. Zolkind, Guangyong Peng, R. Alex Harbison, Rebecca Chernock, Anuraag S. Parikh, Sidharth V. Puram, Itay Tirosh	Weizmann Institute of Science, Rehovot, Israel | Washington University School of Medicine, St. Louis, MO | Columbia University Irving Medical Center, New York, NY	Spatial analysis of head and neck cancer reveals two ecosystems with distinct modes of epithelial-to-mesenchymal transition 4/20/2026 9:00:00 AM | Late-Breaking Research: Bioinformatics, Computational Biology, Systems Biology, and Convergent Science 1 Open abstract	Visium
LB191	Jiaqian Luo, Sizhi P. Gao, Jacob E. Tallman, Fengshen Kuo, Merve Basar, Cansu Yol, Syed M. Alam, Hui Jiang, Xinran Tang, Alejandra Lopez Rojas, Ecenur Turkay, Jonathan E. Rosenberg, Iyer Gopakumar, Eugene J. Pietzak, David B. Solit, Hikmat Al-Ahmadie	Memorial Sloan Kettering Cancer Center, New York, NY	Decoding metastasis and therapy resistance in sarcomatoid bladder cancer 4/20/2026 2:00:00 PM | Late-Breaking Research: Experimental and Molecular Therapeutics 2 Open abstract	Visium
LB237	Wei Zhao, Aaron Rozeboom, Phuc H. Hoang, Tam-Anh Tran, Maria Teresa Landi	National Cancer Inst. Div. of Cancer Epidemiology & Genetics, Bethesda, MD | Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD	High-resolution spatial transcriptomics identifies unique spatial programs in lung adenocarcinoma from never smokers 4/20/2026 2:00:00 PM | Late-Breaking Research: Tumor Biology 1 Open abstract	Xenium; Visium
LB238	Danyelle Hill, Yuxin Jin, Javier Arias-Stella, Joseph Carlson, David Craig, Rania Bassiouni, John Carpten	Beckman Research Institute of The City of Hope, Duarte, CA | The City of Hope, Duarte, CA	Spatial transcriptomics identifies distinct molecular and immune pathways in endometrial cancer in African American women 4/20/2026 2:00:00 PM | Late-Breaking Research: Tumor Biology 1 Open abstract	Visium
LB283	Andrew E. Evans, Ariana A. Entezari, Adi Caspi, Jasmine A. Alvarez, Adam E. Snook, Scott A. Waldman	Thomas Jefferson University Hospital, Philadelphia, PA	Oncogenic WNT/β-catenin signaling reduces MAPK signaling to suppress broad gene expression and promote colorectal cancer progression 4/21/2026 9:00:00 AM | Late-Breaking Research: Molecular/Cellular Biology and Genetics 2 Open abstract	-
LB302	Eva Zhao, Isam Adam, Angela Lincy Prem Antony Samy, Jacob Insua-Rodríguez, Pascal Naef, Sharmila Mallya, Jenny Wu, Delia F. Tifrea, Robert A. Edwards, Ahmed Mohyeldin, Devon A. Lawson	University of California, Irvine, Irvine, CA	Investigation of the immune microenvironment of breast cancer brain metastasis using single-cell spatial genomics 4/21/2026 9:00:00 AM | Late-Breaking Research: Tumor Biology 2 Open abstract	Xenium
LB306	Sylvia Burris, Gurdeep Singh	George Mason University, Fairfax, VA | University of New Mexico Health Sciences Center, Albuquerque, NM	Spatial transcriptomics reveals primary-site endothelial EMT reprogramming that drives immunosuppression in metastatic uveal melanoma and predicts poor survival 4/21/2026 9:00:00 AM | Late-Breaking Research: Tumor Biology 2 Open abstract	Visium
LB425	Traci Hilton, Ryan Meng, Guo Hui Gan, Tarsem Moudgil, Christopher Paustian, Noah Simons, Venkatesh Rajamanickam, Shawn M. Jensen, Elie Adwani, Sierra J. Smith, Matthew H. Taylor, Olivier Fesneau, Thomas M. Duhen, Irene Shih, Myungkyu Jang, Annie Long, Abigail Staeck, Tijana Jovanovic, Brady Bernard, Christie Tanisha, Noriko Iwamoto, Yuriko Minegishi, Koji Ueda, William L. Redmod, Lessli M. Rushforth, Takashi Shimada, Patrick Rethwisch, Carlo B. Bifulco, Hong-ming Hu, Walter J. Urba, Yoshinobu Koguchi, Marcus A. Couey, Richard B. Bell, Jianguo Huang, Eric Tran, Brian Piening, Rom Leidner, Bernard A. Fox	UbiVac, Portland, OR | Earle A. Chiles Research Institute, Portland, OR | Shimadzu Corporation, Kyoto, Japan | Japanese Foundation for Cancer Research, Tokyo, Japan | Ohio State University, Portland, OR | Boston University, Boston, MA	Search for targets of anti-cancer immunity in patients receiving an off-the-shelf cancer’s dark matter vaccine, DPV-001, combined with anti-PD-1 +/- anti-GITR in head and neck squamous cell cancer (HNSCC) 4/22/2026 9:00:00 AM | Late-Breaking Research: Clinical Research 4 Open abstract	-

Abstract #	Authors	Affiliation	Title / Session	Products
65	Luke McNickle, Assya Legrini, Yoana Doncheva, Mari-Claire McGuigan, Ghazal Latifi, Claire Kennedy Dietrich, Molly McKenzie, Phimmada Hatthakarnkul, Tom Wright, Leonor Patricia Schubert Santana, Emma McCargow, Cong Chen, Henry M. Wood, Jon Laye, Gemma Hemmings, Caroline Cartlidge, Derek Magee, Phil Quirke, Joanne Edwards, Nigel Jamieson	School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom | Genomics England Limited, London, United Kingdom | Division of Pathology and Data Analytics, University of Leeds, Leeds, United Kingdom | School of Computer Science, University of Leeds, Leeds, United Kingdom	Integrating spatial transcriptomics and digital pathology with whole-genome data from Genomics England to characterise the tumour and it's microenvironment in colorectal cancer 4/19/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 1 Open abstract	CosMx
687	Amanda Lindberg, Bartosz Sobocki, Patrick Micke, Carina Strell	Immunology, genetics and pathology, Uppsala University, Uppsala, Sweden | Department of Oncology and Radiotherapy, Medical University of Gdańsk, Gdańsk, Poland	In situ KRAS-mapping and spatial -omics characterization in lung premalignancy 4/19/2026 2:00:00 PM | Methods to Measure Tumor Evolution and Heterogeneity Open abstract	CosMx
808	Margaret L. Hoang, Rachel Liu, Dan McGuire, Ashley Heck, Kimberly Young, Megan Vandenberg, Claire Williams, Martin Shelton, Prajan Divakar, Patrick Danaher, Erin Piazza, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Single cell spatial multiomics of TCR and BCR repertoires using CosMx® SMI to characterize immune cell dynamics in PBMCs and tumors 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	CosMx
809	Yi Cui, Claire Williams, Chia-Ying Lee, Chi Phan, Sierra Mckinzie, Shanshan He, Ashley Heck, Kimberley Young, Lidan Wu, John Lyssand, PRAJAN DIVAKAR, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA	Spatially resolved multiomics profiling of glioblastoma reveals molecular signatures of neuropathology and immuno-oncology architecture using CosMx SMI 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	CosMx
1201	Yunhe Liu, Idania Carolina Lubo Julio, Wei Lu, Alejandra G. Serrano, Jean R. Clemenceau, Amber Famiglietti, Karen Colbert, Yibo Dai, Yang Liu, Jun Wang, Jeremy L. Davis, Mingyao Li, Paul F. Mansfield, Tae Hyun Hwang, Luisa M. Solis-Soto, Linghua Wang	Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Surgery, Vanderbilt University Medical Center, Nashville, TN | National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD | Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX | BioChemistry&Molecular Biology, University of Maryland School of Medicine, Baltimore, MD | University of Pennsylvania, Philadelphia, PA | Vice President, Acute Care Services, UT MD Anderson Cancer Ctr., Houston, TX | Department of Translational Molecular Pathology, the university of MD Anderson cancer center, Houston, TX	Spatial 3D and multi-omics mapping of diffuse gastric cancer evolution from preinvasive to invasive lesions in CDH1 mutation carriers 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium; CosMx; GeoMx; G4X
1361	Shilpa S. Dhar, Johnson Amoah, Ferhad Mongal, Liyong Zeng, Aryana S. Bhati, Xueshuai Han, Fang Cao, Tanaya Alexander Washington, MelissaPizzi Pizzi, Bansi Vanparia, Calena J. Brown, Gengyi Zou, Min Gyu Lee, Linghua Wang, Jaffer A. Ajani	GI Medical Oncology, UT MD Anderson Cancer Center, Houston, TX | UT MD Anderson Cancer Center, Houston, TX | University of Houston, Houston, TX | Genome Medicine, UT MD Anderson Cancer Center, Houston, TX | Peking University Health Science Center, Beijing, China | Dept. of Molec. & Cellular Onc., UT MD Anderson Cancer Center, Houston, TX	KDM2A-driven epigenetic reprogramming promotes barrett’s esophagus progression to adenocarcinoma 4/19/2026 4:20:00 PM | Advances in Cancer Epigenetics Open abstract	CosMx
1476	Steven Yan, Limin Jiang, Yan Guo	University of Miami Miller School of Medicine, Miami, FL | University of Miami, Miami, FL	Improve spatial transcriptomic data with integrated hybrid transformer and graph convolutional networks 4/20/2026 9:00:00 AM | Integrative Computational Approaches 1 Open abstract	Xenium; Visium; CosMx
2044	Rachel Liu, Joe Phan, Rustem Khafizov, Kimberly Young, Ashley Heck, Dwayne Dunaway, Sayani Bhattacharjee, Courtney Anderson, Mirko Corselli, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Single-cell spatial profiling microRNA in human colon cancer tissue using high-plex multiomic Spatial Molecular Imaging (SMI) 4/20/2026 9:00:00 AM | MicroRNAs as Cancer Biomarkers, Therapeutic Targets, and Modulators of Treatment Response Open abstract	CosMx
2436	Wenbo Zhu, Hongru Shen, Huijun Wang, Ben Liu, Xiangchun Li, Kexin Chen	Tianjin Medical University Cancer Institute and Hospital, Tianjin, China	Gastric cancer-derived tertiary lymphoid structure score from single-cell spatial transcriptomics with pan-cancer validation for immunotherapy response 4/20/2026 9:00:00 AM | Biomarkers Predictive of Therapeutic Benefit 3 Open abstract	CosMx
2687	Mari-Claire McGuigan, Luke McNickle, Assya Legrini, Ghazal Latifi, Claire Kennedy-Dietrich, Hannah Morgan, Olivia McCabe, Fraser Duthie, Tengyu Zhang, Michail Doukas, Andrea Gonzelz Cisar, Yoana Doncheva, Josefina Martinez Vasquez, Yi Cui, Sanghamithra korukonda, Ashley Heck, Kim Young, Joanne Edwards, Joseph Beechem, Nigel Jamieson	Jamieson Spatial Laboratory, The University of Glasgow, Glasgow, United Kingdom | Glasgow Tissue Research Facility, The University of Glasgow, Glasgow, United Kingdom | Department of Pathology, The Queen Elizabeth University Hospital, Glasgow, United Kingdom | Pathology and Clinical Bioinformatics, Erasmus MC, Rotterdam, Netherlands | R&D, Bruker Spatial Biology, Seattle, WA | Translational Cancer Pathology (Edwards Lab), The University of Glasgow, Glasgow, United Kingdom	First single slide spatially resolved multiomic integration of pancreatic cancer: High-plex proteomic and whole transcriptome analysis 4/20/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 3 Open abstract	CosMx
2708	Robert F. Gruener, Weijie Zhang, Lilin Wang, Adam M. Lee, R. Stephanie Huang	University of Minnesota, College of Pharmacy, Minneapolis, MN | University of Minnesota, Minneapolis, MN | Asst. Professor, Dept. of Medicine, University of Minnesota, Minneapolis, MN	Revealing fibroblast-mediated impacts to therapy response through spatially resolved drug response prediction in lung cancer 4/20/2026 2:00:00 PM | Integration of Clinical and Research Data Open abstract	Xenium; CosMx
3443	Seongyeol Park, Manon de Graaf, Artem Lomakin, Zhicheng Ma, Noah F. Greenwald, Lise Mangiante, Clemens L. Weiss, Brennan Geti Simon, Michael Angelo, Marleen Kok, Christina Curtis	Stanford University School of Medicine, Stanford, CA | The Netherlands Cancer Institute, Amsterdam, Netherlands | Stanford University, Palo Alto, CA	Tumor and microenvironmental co-evolution in metastatic triple-negative breast cancer during immunotherapy 4/20/2026 2:00:00 PM | Microenvironmental Determinants of Therapy Response and Resistance 1 Open abstract	CosMx
3444	Wesley V. Wilson, MacLean P. Nasrallah, Nakial Cross, Yael A. Day, Vanessa Gonzalez, Rachel M. Leskowitz, Amy Marshall, Julie K. Jadlowsky, Gabriela Plesa, Donald L. Siegel, Elizabeth O. Hexner, Joseph A. Fraietta, Carl H. June, Stephen J. Bagley, Donald O’Rourke, Zev Binder, Andrew J. Rech	Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada | Penn Medicine, Philadelphia, PA | Perelman School of Medicine Univ. of Pennsylvania, Philadelphia, PA | CCI, Penn Medicine, Philadelphia, PA | University of Pennsylvania, Philadelphia, PA | Program Director of Translational Research, Abramson Family Cancer Research Inst, University of Pennsylvania, Philadelphia, PA	Spatial profiling of recurrent glioblastoma in a Phase I clinical trial reveals favorable immune remodeling induced by intracerebroventricular CAR T therapy 4/20/2026 2:00:00 PM | Microenvironmental Determinants of Therapy Response and Resistance 1 Open abstract	Visium; CosMx; GeoMx
3943	Shaomiao Xia, Yvonne Xinyi Lim, Min Liu, Bailey Grab, Siddhi Patil, Shiting Li, Laura Rozek, Nisha J. D'silva, Maureen A. Sartor	Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI | University of Michigan School of Dentistry, Ann Arbor, MI | Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI | Georgetown University, Washington, DC | Oncology Department, School of Medicine, Georgetown University, Washington, DC | Assistant Professor, Dept. of Bioinformatics, University of Michigan Medical School, Ann Arbor, MI	Morphology-derived spindle-cell gene signature in HPV+ HNSCC is linked to pEMT, molecular subtype, HPV integration, and recurrence-free survival 4/20/2026 2:00:00 PM | Prognostic Biomarkers 2 Open abstract	CosMx
3951	Assya Legrini, Tengyu Zhang, Mari-Claire McGuigan, Colin Wood, Luke McNickle, Claire Kennedy-Dietrich, Ghazal Latifi, Yoana Doncheva, Josefina Vasquez, Hannah Morgan, Pamela McCall, Michail Doukas, Joanne Edwards, Nigel Jamieson	Univ. of Glasgow, Glasgow, United Kingdom | Glasgow Tissue Research Facility, Univ. of Glasgow, Glasgow, United Kingdom | Erasmus MC, Rotterdam, Netherlands	Spatial mapping of B7-H3 mediated cellular plasticity in treatment naive pancreatic cancer 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx; GeoMx
3953	Matt Lastrapes, Eleanor A. Fallon, Brenda Melendez, Bharat B. Singh, Davis Ingram, Khalida M. Wani, Lon W. Fong, Ashish Damania, Vivian Orellana, Nadim J. Ajami, Jillian Losh, Alexander Lazar, Kanwal Pratap Singh Raghav, John P. Shen, Melissa Taggart, Jennifer A. Wargo, Beth A. Helmink, Paul A. Scheet, Michael Geoffrey White	UT MD Anderson Cancer Center, Houston, TX | Roswell Park Comprehensive Cancer Center, Buffalo, NY	Assessing the role of immune aggregates as potential biomarkers of immunotherapy response in appendiceal adenocarcinoma (AA) using spatial proteomics 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx
3956	Oliver J. De Sa, Megan Hopkins, Angel Arnaout, Arif Awan, Gregory Pond, Jane Bayani, Melanie Spears	Ontario Institute for Cancer Research, Toronto, ON, Canada | Ottawa Hospital Research Institute, Ottawa, ON, Canada | Assistant Professor, Dept. of Oncology, Department of Oncology, McMaster University, Hamilton, ON, Canada	Spatial transcriptomic mapping of ER-positive breast tumors reveals immune pathway remodeling and resistance mechanisms following anti-PD-1 therapy 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx
3966	Megan Hopkins, Oliver De Sa, Dan Dion, Vida Talebian, Jane Bayani, Melanie Spears	Diagnostic Development, Ontario Institute for Cancer Research, Toronto, ON, Canada | Ontario Institute for Cancer Research, Toronto, ON, Canada	In situ spatial multiomic profiling of breast cancer tissue utilizing the CosMx Spatial Molecular Imager 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx
3967	Megan Hopkins, Oliver De Sa, Dan Dion, Vida Talebian, Jane Bayani, Melanie Spears	Ontario Institute for Cancer Research, Toronto, ON, Canada	Spatial whole transcriptomic profiling of breast cancer tissue with CosMx Spatial Molecular Imager 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx
3973	Tim Schunk, Tim Mandelkow, Shida Xiong, Jonas Raedler, Rodler Severin, Philipp Nuhn, Anne Letsch, Marion van Macklenbergh, Jan Weitkamp, Jakob Kohler, Arne Christians, Oliver Braubach, Steve Lott, Micaela Mathiak, Gavin Gordon, Björn Konukiewitz, Christoph Rocken, Niclas Christian Blessin	Universitätsklinikum Schleswig-Holstein, Kiel, Germany | Bruker Spatial Biology | Canopy Biosciences, St. Louis, CA | Bruker Spatial Biology, St. Louis, CA | Professor, Dept. of Pathology, Christian-Albrechts-University, Kiel, Germany	A framework for antibody validation via spatial proteo-transcriptomics using the CellScape platform 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx; CellScape
3974	Claire Williams, Patrick Danaher, Megan Vandenberg, Martin Shelton, Mirko Corselli, Christine Kang, John Lyssand, Joseph Beechem	Bruker Spatial Biology, Seattle, WA	Decoding cancer hallmarks through single-cell whole transcriptome imaging in invasive ductal carcinoma 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx
4795	Michael Emilio Patrick, Wei Yang, Liang Zhang, Isabel Lee, Stefan-Laural Rogers, Shanshan He, Christina Bailey, John Lyssand, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA	Investigating HER2+ tumor cell motility and angiogenesis in FFPE breast cancer in space and at scale with CosMx and nCounter multiomics 4/21/2026 9:00:00 AM | Angiogenesis Open abstract	CosMx; nCounter
4946	Patrick Czabala, Yang Zhao, John Klement, Dafeng Yang, Dakota Poschel, Kendra Fick, Zainab Tiamiyu, Martina Zoccheddu, Kristen Carver, Priscilla Redd, Patricia Schoenlein, Jennifer Waller, Huidong Shi, Kebin Liu	Biochemistry and Molecular Biology, Augusta University, Augusta, GA | Biostatistics, Data Science, and Epidemiology, School of Public Health, Augusta University, Augusta, GA	Osteopontin spatially rewires tumor-immune niches to promote colon cancer liver metastasis 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	CosMx
4948	Chuyan Liu, Hang Yin, Joon Sang Lee, Julien Tessier, Junbum Kim, Donald Jackson, Angela Hadjipanayis, Olivier Elemento	Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY | Department of Systems and Computational Biomedicine, Weill Cornell Medicine, New York, NY | Precision Oncology, Sanofi, Cambridge, MA | Precision Medicine and Computational Biology, Sanofi, Cambridge, MA | Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY	Spatial architectures of colorectal cancer microenvironment underlying immune checkpoint inhibitor response 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	CosMx
4961	Samarth Singhal, Amber Rockson, Hanina Hibshoosh, Parin Shah, Fatemeh Derakhshan, Diane Chen, Alireza Salem, Benjamin Izar, Kevin L. Gardner, Coral O. Omene, Daniel Fernandez, Adrienne L. Castillo, Emma Armstrong, Ijeamaka Anyene Fumagalli, Elizabeth M. Cespedes Feliciano, Sandeep K. Singhal, Adana A. M. Llanos	University of North Dakota | Epidemiology, Columbia University Mailman School of Public Health, New York, NY | Columbia University Irving Medical Center, New York, NY | Vagelos College of Physicians & Surgeons, New York, NY | Clinical Instructor, Dept. of Medicine, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ | Kaiser Permanente Northern California, Oakland, CA | Kaiser Permanente, Oakland, CA | University of North Dakota, Grand Forks, ND	Cell type-specific adipokine signaling networks in the breast tumor microenvironment uncovered by high-plex spatial imaging 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	CosMx
4984	Joseph Zenga, Musaddiq Awan, Fumou Sun, Stuart J. Wong, Abdullah Memon, Tyce Kearl, Ean Norenberg, Margaret L. Hoang, Joseph M. Beechem, Eric Hobbs, Ashley Heck, Rachel Liu, Daniel McGuire, Erin Piazza, Peiman Hematti, Heather Himburg	Medical College of Wisconsin, Milwaukee, WI | Bruker Spatial Biology, Seattle, WA | Bruker Spatial Biology, Piedmont, CA | Bruker Cellular Analysis, Emeryville, CA	Dissociative, spatial, and functional single-cell profiling reveals antigen-driven exhaustion and chemotactic failure of tumor-reactive T cells in HPV-negative HNSCC 4/21/2026 9:00:00 AM | Tumor-Immune Crosstalk Open abstract	CosMx; Beacon
5499	Xiyu Peng, James Smithy, Mohammad Yosofvand, Caroline Kostrzewa, Fiona Ehrich, MaryLena Bleile, Jasme Lee, Michael A. Postow, Margaret K. Callahan, Katherine Panageas, Ronglai Shen	Texas A&M University, College Station, TX | Memorial Sloan Kettering Cancer Center, New York, NY | Univ. of Connecticut School of Medicine, Farmington, CT	SpatialTopic exploring tumor ecosystem in 3D multiplexed imaging of melanoma 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; CosMx
5524	Mary Goldman, Brian Craft, Cally Lin, Jingchun Zhu, David Haussler	UC Santa Cruz Genomics Institute, Santa Cruz, CA | Stanford University, San Francisco, CA | Investigator/Distinguished Professor, Ctr. For Bio. Sci. & Eng., UC Santa Cruz, Santa Cruz, CA	Visualization and analysis of cancer genomics data using UCSC Xena 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; Visium; Chromium; CosMx; MerFISH
5616	Cole W. Peters, Miriam Valenzuela Cardenas, Moe Kawakami, Jaden Nguyen, Allison Flores, Andrew Dinh, Stephen Ma, Daniel G. Chen, Valerie Rezek, Scott Kitchen, Katie M. Campbell, Melissa Lechner, Theodore Scott Nowicki	UCLA - University of California Los Angeles, Los Angeles, CA | Pediatric Oncology, University of California, Los Angeles, Los Angeles, CA | University of California, Los Angeles, Los Angeles, CA	Tumor necrosis factor-alpha armed TCR-T and CAR-T cells for solid tumors provide superior anticancer activity in the absence of toxicity 4/21/2026 2:00:00 PM | TCR and Autologous T Cell Therapies Open abstract	CosMx
5923	Yi Cui, Marena I. Trinidad, Nurel Arriaran, Isabel Lee, Chia-Ying Lee, Shanshan He, Timothy Riordan, Joseph Beechem, Alexander E. Ehrenberg, Hanqin Li	Bruker Spatial Biology, Seattle, WA | Innovative Genomics Institute, Berkeley, CA	Optical pooled CRISPR screening coupling multiplexed guide RNA detection and single-cell spatial multi-omics 4/21/2026 2:00:00 PM | Genetic and Transcriptomic Dissection of Cancer Evolution Open abstract	CosMx
5953	Michael Patrick, Liang Zhang, Isabel Lee, Shanshan He, Martin Shelton, John Lyssand, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA	Unlocking new frontiers in mouse research by exploring the whole-transcriptome in space and time with mouse embryo stages E11 - E14 4/21/2026 2:00:00 PM | Mechanisms and Dynamics of Gene Expression Open abstract	CosMx
6113	Yufei Wang, Jae-Won Cho, Yasmin Nabil Laimon, Wenxin Xu, Kun Huang, Aseman Bagheri Sheshdeh, Nithyassree Murugan, Hsien-Chi Yuan, Jon Wee, David Alexander Braun, Toni K. Choueiri, Catherine J. Wu, Sabina Signoretti, Gordon J. Freeman, Martin Hemberg, Wayne A. Marasco	Dana-Farber Cancer Institute, Boston, MA | Brigham and Women's Hospital, Boston, MA | Yale School of Medicine, New Haven, CT | Associate Professor, Dana-Farber Cancer Institute, Boston, MA	ccRCC lung metastases harbor cancer associated fibroblast lymphocyte exclusion sites that form a confined TME as revealed by single cell and spatial multi-omics 4/21/2026 2:00:00 PM | Metastasis and Organ-Specific Microenvironmental Evolution Open abstract	Xenium; CosMx
6115	Tae Hee Hong, Hansoll Na, Chung Lee, Young Ho Yang, Ha Eun Kim, Byung Jo Park, Min Hee Hong, Hye Ryun Kim, Hyun Ki Kim, Dae Joon Kim	Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of | Department of Pathology, Yonsei University College of Medicine, Seoul, Korea, Republic of | Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea, Republic of	Deciphering tumor microenvironment dynamics in tumorigenesis and lymph node metastasis of esophageal squamous cell carcinoma using single-cell and spatial transcriptomics 4/21/2026 2:00:00 PM | Metastasis and Organ-Specific Microenvironmental Evolution Open abstract	CosMx
6198	Shaocheng Wu, Eric Lee, Anne-Sophie Fratzscher, Andrew Lytle, Spencer D. Martin, David G. Huntsman, David W. Scott, Christian Steidl, Andrew Roth	BC Cancer Agency, Vancouver, BC, Canada | University of British Columbia, Vancouver, BC, Canada	Single cell spatial multi-omic characterization of the tumor microenvironment in transformed follicular lymphoma 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	CosMx
6199	Tengyu Zhang, Assya Legrini, Mari-Claire McGuigan, Stephan B. Dreyer, Ghazal Latifi, Claire Kennedy Dietrich, Hannah Morgan, Eva Verkolf, Virginia Padoan, Yoana Doncheva, Joao Da Silva Filho, Michail Doukas, Bas Groot Koerkamp, Joanne Edwards, Nigel Jamieson	School of Cancer Science, Univ. of Glasgow, Glasgow, United Kingdom | Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands | School of Infection and Immunity, Univ. of Glasgow, Glasgow, United Kingdom | Pathology and Clinical Bioinformatics, Erasmus Medical Centre, Rotterdam, Netherlands	Spatially revealed malignant and microenvironment ecosystems in PanIN- and IPMN-derived PDAC 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	CosMx
6206	Dexter Wing Lun Lee, Kaiyan Xu, Parker Li, Joshua Jing Xi Li, Wei Dai, Karrie Kiang, Gilberto Ka-Kit Leung, Aya El Helali	Department of Clinical Oncology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, Hong Kong | Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong, Hong Kong | School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong | Department of Pathology, School of Clinical Medicine,, The University of Hong Kong, Hong Kong, Hong Kong | Department of Surgery, School of Clinical Medicine, The University of Hong Kong, Hong Kong, Hong Kong	Spatially resolved cell-cell architecture in WHO grade 4 IDH-wildtype glioblastoma revealed by CosMx 6K discovery panel 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	CosMx
6208	Liang Zhang, Isabel Lee, Shanshan He, Martin Shelton, Owen J. Sansom, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA | Cancer Research UK Scotland Institute, Glasgow, United Kingdom	Subcellular imaging of murine models of metastatic colorectal cancer using a whole transcriptome spatial molecular imaging panel 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	CosMx
6470	Nakial C. W. Cross, Yael A. Day, Sonia Ndeupen, Vanessa E. Gonzalez, Zhen Miao, Sam I. Kim, Rachel M. Leskowitz, Amy Marshall, Julie K. Jadlowsky, Gabriela Plesa, Donald L. Siegel, Elizabeth O. Hexner, Jakub Svoboda, Stephen J. Schuster, Nancy R. Zhang, Joseph A. Fraietta, Andrew J. Rech, Carl H. June	Perelman School of Medicine Univ. of Pennsylvania, Philadelphia, PA | Statistics & Data Analysis, Wharton School Univ. of Pennsylvania, Philadelphia, PA	Spatial remodeling of the tumor microenvironment by IL-18-armored CD19 CAR T cells is associated with durable remission in relapsed or refractory lymphoma 4/21/2026 2:00:00 PM | Clinical Correlates of Immunotherapy Open abstract	CosMx; GeoMx
6549	Yi Cui, Moumita Nath, Michael Emilio Patrick, Claire Williams, Daniel McGuire, Jobin K. Paul, Kowshik Jaganathan, Biswajit Das, Mohit Malhotra, Shanshan He, Joseph M. Beechem, Satish Sankaran	Bruker Spatial Biology, Seattle, WA | Farcast Biosciences India, Bengaluru, India	Integrating functional biosignatures and same-cell spatial multiomics to predict synergistic benefit of combination checkpoint therapy in head and neck cancer 4/21/2026 2:00:00 PM | Immune Checkpoint Blockade Open abstract	CosMx; nCounter
6591	Daniel Jimenez-Sanchez, Matthew H. Ingalls, Sanghamithra korukonda, Brian J. Lane, Isabella Marie Peshek, Patrick Danaher, Prajan Divakar, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO | Bruker Spatial Biology, Seattle, WA | Division of Gastroenterology, Northwestern University, Chicago, IL	Cross platform same slide multi-omics reveals Treg heterogeneity and links to spatial niche variability in pre-cancerous colonic inflammation 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	CosMx; CellScape
6755	M. Dhainaut, L. Zhang, M. Meister, A. Mavropoulos, A. Benz, I. Lee, S. McKinzie, D. Millman, D. Tran, D. Ovando, L. Cavalcante, K. Mitchell, E. Margalit, D. Antonio, A. Mahajan, A. Salm, E. Siefkas, F. Fernandez, H. Kaplan, H. Winters, J. Schmidt, J. Tea, J. Decalf, L. Ryan, M. Zolanvari, N. Snell, R. Schiemann, R. Collins, R. Huang, Y. Xie, Y. Falanga, S. Virani, L. Padron, E. Corse, S. He, D. Bear, J. M. Beechem, R. W. Alfa; Noetik, San Francisco, CA, Bruker Spatial Biology, Seattle, WA		Unbiased phenotyping of CRISPR-edited tumors with Perturb-map and subcellular imaging of the mouse whole transcriptome (22,000-plex) 4/21/2026 4:05:00 PM | Spatial Biomarkers at Single-Cell Resolution: Mapping Tumor Ecosystems with Proteomics, Transcriptomics, and AI Open abstract	CosMx
6895	Yufeng He, Yanping Zhao, Rui Zhang, Heli Yang, Zhaode Bu, Yuan Luo, Deng Pan, Zexian Zeng	Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China | Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China | Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Peking University, Beijing, China | Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL | Tsinghua-Peking Center for Life Sciences, Department of Basic Medical Sciences, Tsinghua University, Beijing, China	DISSECT integrates cytological images and spatial transcriptomics for cell segmentation 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	Xenium; Visium; CosMx
7235	Yi Cui, Huy Nguyen, Andrea Floris, David King, Serdar Tulu, David Castillo, Shanshan He, Shyamtanu Chattoraj, Jude Dunne, Mirko Corselli, John Lyssand, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA | Bruker Spatial Genomics, San Jose, CA	Integrated spatial multiomic profiling of 3D genome architecture and transcriptome-wide gene expression in breast cancer models 4/22/2026 9:00:00 AM | Chromatin Architecture and Regulatory Landscapes Open abstract	CosMx; PaintScape
CT111	Phuong A. Nguyen, Peter M. Szabo, Joseph Kotler, Simon Chow, Bijal Kakrecha, Nnamdi Onochie, Fanni Santa, Michaela Bowden, Oliver Jonas, Matthew Mossanen, Evisa Gjini	Flare Therapeutics, Cambridge, MA | Mass General Brigham, Boston, MA | Dana-Farber Cancer Institute, Boston, MA | Kibur Medical, Boston, MA	Phase 0 intratumoral microdevice study of FX-909 in bladder cancer demonstrates on-target anti-tumor activity and immune modulation, enhanced in combination with anti-PD-1 4/20/2026 2:00:00 PM | Phase 0 and First-in-Human Phase I Clinical Trials Open abstract	CosMx
LB009	Ugonna Ezuma-Igwe, Xi Sun, Abigail G. Branch, Sangmin Kim, Rohan Kanakamedala, Payton Stevens, Jiang Wang, Syed A. Ahmad, Davendra Sohal, Petros G. Nikolinakos, James Griffin, Yana Zavros	University of Georgia School of Medicine, Athens, GA | Medical College of Georgia, Augusta University/University of Georgia Medical Partnership, Athens, GA | Miami University, Department of Biological Sciences, Oxford, OH | Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH | Department of Surgery, Division of Surgical Oncology, University of Cincinnati, Cincinnati, OH | Hematology and Medical Oncology, University of Cincinnati, Cincinnati, OH | University Cancer and Blood Center, Athens, GA	Mapping the spatiotemporal dynamics of CD44v9 reveals a senescent cell therapy-resistant niche in pancreatic cancer 4/19/2026 2:00:00 PM | Late-Breaking Research: Clinical Research 1 Open abstract	CosMx
LB017	Xi Sun, Ugonna Ezuma-Igwe, Abigail G. Branch, Jiang Wang, Juanita L. Merchant, Syed A. Ahmad, Davendra Sohal, Petros G. Nikolinankos, James Griffin, Yana Zavros	University of Georgia, Athens, GA | Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH | Division of Gastroenterology and Hepatology, College of Medicine, University of Arizona, Tucson, AZ | Department of Surgery, Division of Surgical Oncology, University of Cincinnati, Cincinnati, OH | Hematology and Medical Oncology, University of Cincinnati, Cincinnati, OH | University Cancer and Blood Center, Athens, GA	Cluster of differentiation 44 variant isoform 9 defines cancer stem cell reservoirs in pancreatic intraepithelial neoplastic spatial niches 4/19/2026 2:00:00 PM | Late-Breaking Research: Clinical Research 1 Open abstract	CosMx
LB124	Abigail G. Branch, Xi Sun, Arturo A. Lujan, Jia-Ren Lin, Yi-Chien Wu, Jennifer Eschbacher, Beth Hermes, Andrew S. Little, Yoshie Umemura, Sandro Santagata, Yana Zavros	University of Georgia, Athens, GA | University of Arizona College of Medicine, Tucson, AZ | Brigham and Women's Hospital, Harvard Medical School Department of Pathology, Boston, MA | Brigham and Women's Hospital, Harvard Medical School Department of Pa-thology, Boston, MA | Department of Neuropathology, Barrow Neurological Institute, Pheonix, AZ | Department of Neuropathology, Barrow Neurological Institute, Phoenix, AZ | Department of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ | Department of Neuro-oncology, Barrow Neurological Institute, Phoenix, AZ	Patient-derived organoid-immune cell co-cultures and spatial biology support a CD44v9 cancer stem cell-directed therapeutic strategy for adamantinomatous craniopharyngioma 4/20/2026 9:00:00 AM | Late-Breaking Research: Clinical Research 2 Open abstract	CosMx
LB234	Jayati Chakrabarti, Saptarshi Mallick, Xi Sun, Ugonna Ezuma-Igwe, Abigail G. Branch, Jiang Wang, Sangmin Kim, Rohan Kanakamedala, Syed A. Ahmad, Davendra Sohal, Rachna Shroff, Yana Zavros	University of Arizona College of Medicine, Tucson, AZ | University of Georgia, Athens, GA | Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH | Medical College of Georgia, Augusta University/University of Georgia Medical Partnership, Athens, GA | Department of Surgery, Division of Surgical Oncology, University of Cincinnati, Cincinnati, OH | Hematology and Medical Oncology, University of Cincinnati, Cincinnati, OH | Division of Hematology and Oncology, University of Arizona, College of Medicine, Tucson, AZ	Cabozantinib remodels the pancreatic tumor microenvironment to potentiate immunotherapy 4/20/2026 2:00:00 PM | Late-Breaking Research: Tumor Biology 1 Open abstract	CosMx
LB427	Giovanni Medico, Giorgia Zanetti, Giorgio Bertolazzi, Francesco Vallania, Paul Zumbo, Maider Amiama, Doron Betel, Maria Cacciapuoti, Abigail Taylor, Clarisse Kayembe, Sanjay Patel, Arvin Ruiz, Jennifer Ziello, Jason Weirather, Gulpreet Kaur, Luca Cappelli, Luca Paruzzo, Marco Ruella, Zhenyuan Dong, Larry Kwak, Nicolás Di Siervi, Maria Revuelta, Claudio Tripodo, Leandro Cerchietti, Giorgio Inghirami	Weill Cornell Medicine, New York, NY | Columbia University, New York, NY | Kore University of Enna, Enna, Italy | immunoLogic inc., San Francisco, CA | Cell Signaling Technology, Beverly, MA | Elucidate Bio, Medford, MA | Sapienza University of Rome, Rome, Italy | Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA | City of Hope Comprehensive Cancer Center, Duarte, CA | IFOM ETS-The AIRC Institute of Molecular Oncology, Milan, Italy	Humanized PDX models uncover drug-reversible epigenetic immune exclusion governing T-cell therapy response in DLBCL, captured in patients by EPICORE stratifier 4/22/2026 9:00:00 AM | Late-Breaking Research: Clinical Research 4 Open abstract	CosMx

Abstract #	Authors	Affiliation	Title / Session	Products
89	Vibha R. Rao, Marvin Escobar Barajas, Candice C. Black, Madhumala K. Sadanandappa, Scott M. Palisoul, Adrienne A. Workman, Todd A. MacKenzie, Louis J. Vaickus, Mary D. Chamberlin, George J. Zanazzi, Shrey S. Sukhadia	Pathology and Laboratory Medicine, Dartmouth Health, Lebanon, NH | Dartmouth College, Hanover, NH	TissueTrek: An interactive multimodal web-based platform for exploring spatial morphology-molecular relationships in cancer 4/19/2026 2:00:00 PM | Digital Pathology 1 Open abstract	GeoMx
773	KENTA MANABE, Atsushi Matsuoka, Kazuhiko Shien, Shuta Tomida, Hidejiro Torigoe, Kazuya Hisamatsu, Ryota Fujiwara, Kosei Ishimura, Shunsuke Mori, Ryunosuke Fujii, Asuka Mimata, Kazuhiro Okada, Ryo Yoshichika, Mao Yoshikawa, Yuma Fukumoto, Haruchika Yamamoto, Kumi Nakajima, Shin Tanaka, Ken Suzawa, Kentaroh Miyoshi, Mikio Okazaki, Seiichiro Sugimoto, Shinichi Toyooka	Thoracic, Breast and Endocrinological Surgery, Okayama Univ. Graduate School of Med., Dentistry & Pharm. Sci., Okayama, Japan | Center for Comprehensive Genomic Medicine, Okayama University Hospital, Okayama, Japan	Single-cell and spatial transcriptomic profiling reveal fibrosis-related tumor states in lung squamous cell carcinoma associated with idiopathic pulmonary fibrosis 4/19/2026 2:00:00 PM | Physicochemical Modulation of Cancer Ecosystems: Mechanical Forces, Hypoxia, and Acidosis Open abstract	GeoMx
796	Min Qing, Qibiao Wu, Xuesong Lyu, Tao Chen, Mingxuan Xia, Joshua J. Rusbuldt, Denis Smirnov, Flora Berisha, Longen Zhou, Chia-Jui Yen	Johnson & Johnson, Shanghai, China | Johnson & Johnson, Spring House, PA | National Cheng Kung University Hospital, Taiwan, China	Digital spatial profiling reveals immune heterogeneity across tumor and stromal compartments in hepatocellular carcinoma 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	GeoMx
803	Prerana Sensharma, Huidan Zuo, Melanie Dawe, Megan Hopkins, Zeynep Baskurt, Osvaldo Espin-Garcia, Philippe L. Bedard, Melanie Spears, Susan J. Done	Medical Biophysics, University of Toronto, Toronto, ON, Canada | Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada | Princess Margaret Cancer Center, Toronto, ON, Canada | Ontario Institute for Cancer Research, Toronto, ON, Canada | Department of Biostatistics, Princess Margaret Cancer Center, Toronto, ON, Canada | UHN-Toronto General Hospital, Toronto, ON, Canada	A spatial profiling approach to evaluating the prognostic impact of heterogeneity in the triple-negative breast cancer immune microenvironment 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	GeoMx
1201	Yunhe Liu, Idania Carolina Lubo Julio, Wei Lu, Alejandra G. Serrano, Jean R. Clemenceau, Amber Famiglietti, Karen Colbert, Yibo Dai, Yang Liu, Jun Wang, Jeremy L. Davis, Mingyao Li, Paul F. Mansfield, Tae Hyun Hwang, Luisa M. Solis-Soto, Linghua Wang	Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Surgery, Vanderbilt University Medical Center, Nashville, TN | National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD | Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX | BioChemistry&Molecular Biology, University of Maryland School of Medicine, Baltimore, MD | University of Pennsylvania, Philadelphia, PA | Vice President, Acute Care Services, UT MD Anderson Cancer Ctr., Houston, TX | Department of Translational Molecular Pathology, the university of MD Anderson cancer center, Houston, TX	Spatial 3D and multi-omics mapping of diffuse gastric cancer evolution from preinvasive to invasive lesions in CDH1 mutation carriers 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium; CosMx; GeoMx; G4X
1202	Minjun Kim, Mustafa Soytas, Burge Ulukan, Tamiko Nishimura, Senthilkumar Kailasam, Ariel Madrigal, Zohreh Mehrjoo, Kate Glennon, Eleonora Scarlata, Madeleine Arseneault, Morag Park, Hamed Najafabadi, Fadi Brimo, Ozgur Sahin, Simon Tanguay, Yasser Riazalhosseini	Victor Phillip Dahdaleh Institute of Genomic Medicine, McGill University, Montréal, QC, Canada | Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of of South Carolina, Charleston, SC | Division of Urology, Department of Surgery, McGill University, Montréal, QC, Canada | Goodman Cancer Institute, McGill University, Montréal, QC, Canada | Department of Pathology, McGill University, Montréal, QC, Canada	Spatially-resolved transcriptome analysis of renal tumors with sarcomatoid/rhabdoid dedifferentiation uncovers underlying biology and new biomarkers relevant to these tumors 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	GeoMx
1220	Mengni He, Charles J. Robbins, Julia Benanto, Thazin Nwe Aung, Yalai Bai, Ian E. Krop, David L. Rimm	Yale University, New Haven, CT | Yale School of Medicine, New Haven, CT	Spatial transcriptomics revealed potential resistance and response factors of sacituzumab govitecan in metastatic breast cancer 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	GeoMx
1222	Charles J. Robbins, Mengni He, Julia Benanto, Thazin Nwe Aung, Yalai Bai, Ian E. Krop, David L. Rimm	Yale School of Medicine, New Haven, CT	Spatial transcriptomics of trastuzumab deruxtecan-treated metastatic breast cancer identifies candidate response and resistance factors 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	GeoMx
1412	Rongting Huang, Diane Libert, Arslan Kasimov, Leandra Kingsley, Sahar Nasr, Reem Al-Humadi, Lindsey A. Finch, Elisabeth Diver, Ravali A. Reddy, Babak Litkouhi, Kristin Bixel, Sizun Jiang, Brooke Howitt	Stanford University, Stanford, CA | The University of Texas MD Anderson Cancer Center, Houston, TX | Harvard Medical School, Boston, MA	Informatics-driven spatial-omics for cancer immunotherapy discovery in gynecologic cancers 4/20/2026 9:00:00 AM | Application of Bioinformatics to Cancer Biology 2 Open abstract	GeoMx
1589	Marika Viatore, Rebecca Polidori, Anna Rita Putignano, Arturo Bonometti, Silvia Uccella, Silvia Bozzarelli, Gianluca Basso, Marco Erreni, Capretti Giovanni, Vincenzo Corbo, Alberto Mantovani, Massimo Locati, Federica Marchesi	University of Milan, Milan, Italy | IRCCS Humanitas Research Hospital, Rozzano, Italy | Dept of Immunology and Inflammation, Humanitas Clinical and Research Center, Milano, Italy | University of Verona, Verona, Italy | IRCCS Istituto Clinico Humanitas, Pieve Emanuele, Italy	Spatial and molecular profiling of multinucleated giant macrophages in pancreatic ductal adenocarcinoma 4/20/2026 9:00:00 AM | Innate Immunity in Cancer Open abstract	GeoMx
2089	Yasmine Ilkhani, Sirine Bouabda-Barc, Rachel Chevalier, Orlando Yuan, Jose Joao Mansure, Madhuri Koti, Wassim Kassouf, Éva Michaud	Urologic Oncology Research Division, Cancer Research Program, Research Institute of the McGill University Health Center, Montréal, QC, Canada | Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada | Department of Surgery, Division of Surgery, Cancer Research Program, McGill University, Montréal, QC, Canada	Sex-specific IgA secretion in muscle-invasive bladder cancer: A preliminary study 4/20/2026 9:00:00 AM | Aging and Host Determinants of Tumor Progression: The Macroenvironmental Axis Open abstract	GeoMx
2217	Shoko Kure, Giorgia Brambilla Pisoni, Saba Tabasum, Xiaoyu Li, Jingjing Li, Yao Yu Yeo, Sizun Jiang, Harrison Olszewski, Nicholas C. Weaver, Kathleen L. Pfaff, Jason L. Weirather, Ian D. Dryg, Scott J. Rodig, Frank S. Hodi	Medical Oncology, Dana-Farber Cancer Institute, Boston, MA | Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA | Tissue Biomarker Lab, Dana-Farber Cancer Institute, Boston, MA | Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA | Department of Pathology, Brigham & Women's Hospital, Boston, MA	Immune-active and mesenchymal endothelial programs define TLS presence in the tumor microenvironment 4/20/2026 9:00:00 AM | Tertiary Lymphoid Structures in Cancer Open abstract	GeoMx
2220	Zhihan Liang, Ada Junquera, Hanna Elomaa, Joona Sarkkinen, Iga Niemiec, Ziqi Kang, Oskari Lehtonen, Lina Maltrovsky, Saundarya Shah, Aleksandra Shabanova, Matilda Salko, Ulla-Maija Haltia, Eliisa Kekäläinen, Anni Virtanen, Anniina Farkkila	Research Program in Systems Oncology, University of Helsinki, Helsinki, Finland | Translational Immunology Research Program, University of Helsinki and Helsinki University Hospital, Helsinki, Finland | Department of Obstetrics and Gynecology, and Clinical Trials Unit, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland | Department of Pathology, University of Helsinki and HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland	A spatially resolved multi-omics atlas of tertiary lymphoid structures in ovarian cancer 4/20/2026 9:00:00 AM | Tertiary Lymphoid Structures in Cancer Open abstract	GeoMx
2298	Rhitajit Sarkar, Shilpa Thakur, Gus Fridell, Elijah Edmondson, Sonam Kumari, Joanna KLUBO-GWIEZDZINSKA	Metabolic Diseases Branch, NIH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Bethesda, MD | National Institutes of Health, Bethesda, MD | Johns Hopkins University, Baltimore, MD | National Institutes of Health, Reston, VA	Spatial immune profiling reveals varying tumor microenvironments in papillary thyroid microcarcinoma 4/20/2026 9:00:00 AM | Hormone Receptor Signaling and Therapeutic Targeting Open abstract	GeoMx; nCounter
2564	Fatima Inigo, Jose Mansure, Eva Michaud, Brian Meehan, Tanner Connell, Ciriaco Piccirillo, Wassim Kassouf	Cancer Research Program, McGill University Health Centre, Montréal, QC, Canada | Cancer and Angiogenesis, McGill University Health Centre, Montréal, QC, Canada | Medical Physics Unit, McGill University Health Centre, Montréal, QC, Canada | Microbiology and Immunology, McGill University Health Centre, Montréal, QC, Canada | Surgery, Division of Adult Urology, McGill University Health Centre, Montréal, QC, Canada	Investigating the combination of natural killer immunotherapy with radiation therapy for muscle invasive bladder cancer 4/20/2026 9:00:00 AM | Immunomodulatory Effects of Targeted Therapies Open abstract	GeoMx
3444	Wesley V. Wilson, MacLean P. Nasrallah, Nakial Cross, Yael A. Day, Vanessa Gonzalez, Rachel M. Leskowitz, Amy Marshall, Julie K. Jadlowsky, Gabriela Plesa, Donald L. Siegel, Elizabeth O. Hexner, Joseph A. Fraietta, Carl H. June, Stephen J. Bagley, Donald O’Rourke, Zev Binder, Andrew J. Rech	Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada | Penn Medicine, Philadelphia, PA | Perelman School of Medicine Univ. of Pennsylvania, Philadelphia, PA | CCI, Penn Medicine, Philadelphia, PA | University of Pennsylvania, Philadelphia, PA | Program Director of Translational Research, Abramson Family Cancer Research Inst, University of Pennsylvania, Philadelphia, PA	Spatial profiling of recurrent glioblastoma in a Phase I clinical trial reveals favorable immune remodeling induced by intracerebroventricular CAR T therapy 4/20/2026 2:00:00 PM | Microenvironmental Determinants of Therapy Response and Resistance 1 Open abstract	Visium; CosMx; GeoMx
3886	Yu Jin Kim, Jeongman Park, Woo Young Kwon, Jaejoon Lim, Sung Hwan Lee	Department of Biomedical Science, College of Life Science, CHA University, Seongnam-si, Korea, Republic of | Department of Medicine, Hallym University, Chuncheon-si, Korea, Republic of | CHA University, Seoul, Korea, Republic of | 2Department of Neurosurgery, Bundang CHA Medical Center, Seongnam-si, Korea, Republic of | CHA University, Seongnam-si, Korea, Republic of	A novel glioblastoma subtype classification using hallmark gene set signatures: Association between poor prognosis and TP53 downstream pathway 4/20/2026 2:00:00 PM | Molecular Classification and Tumor Biology in Cancer Open abstract	GeoMx
3951	Assya Legrini, Tengyu Zhang, Mari-Claire McGuigan, Colin Wood, Luke McNickle, Claire Kennedy-Dietrich, Ghazal Latifi, Yoana Doncheva, Josefina Vasquez, Hannah Morgan, Pamela McCall, Michail Doukas, Joanne Edwards, Nigel Jamieson	Univ. of Glasgow, Glasgow, United Kingdom | Glasgow Tissue Research Facility, Univ. of Glasgow, Glasgow, United Kingdom | Erasmus MC, Rotterdam, Netherlands	Spatial mapping of B7-H3 mediated cellular plasticity in treatment naive pancreatic cancer 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx; GeoMx
3960	Yeseul Kim, Yoseob Lee, Harim Oh, You-Na Sung, Yoo Jin Lee, Yona Kim, Inho Park, Jinhyuk Bhin, Su-Jin Shin	Department of pathology, Korea University Anam Hospital, Seoul, Korea, Republic of | Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Korea, Republic of | Department of pathology, Gangnam Severance Hospital, Seoul, Korea, Republic of	Spatially resolved transcriptomic signatures of gallbladder carcinogenesis from precursor to undifferentiated stages 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	GeoMx
4018	M. Dehankar, L. A. Boardman, D. O'Brien, E. A. Thompson, J. M. Kachergus, J. Shi, A. Abyzov, M. Suvakov, R. P. Graham, C. Wang; Mayo Clinic, Rochester, MN, Ambry Genetics, Aliso Viejo, CA, Mayo Clinic, Jacksonville, FL		Stromal immune composition significantly contributes to adenomatous polyp recurrence or progression to cancer 4/20/2026 3:20:00 PM | Biomarkers That Change Management: Predicting Therapy Benefit, Progression, and Metastatic Risk Open abstract	GeoMx
4146	Ziyin Huang, Kristen E. Rhodin, Rami Al-Rohil, Viviana Geron, Arul M. Chinnaiyan, Margaret H. O'Connor, Christina Vadala Angeles, Smita K. Nair, Georgia M. Beasley, Matthew K. Iyer	University of Michigan, Ann Arbor, MI | Duke University, Durham, NC | University North Carolina, Chapel Hill, NC	Melanocytic transcriptional state is an independent marker of survival in metastatic melanoma 4/21/2026 9:00:00 AM | Application of Bioinformatics to Cancer Biology 4 Open abstract	GeoMx
4166	Ryunosuke Fujii, Kousei Ishimura, Kazuhiko Shien, Shuta Tomida, Kenta Manabe, Shunsuke Mori, Kazuya Hisamatsu, Ryota Fujiwara, Atsushi Matsuoka, Ryo Yoshichika, Kazuhiro Okada, Yuma Fukumoto, Haruchika Yamamoto, Kumi Nakajima, Shin Tanaka, Hidejiro Torigoe, Ken Suzawa, Kentaroh Miyoshi, Mikio Okazaki, Seiichiro Sugimoto, Hirofumi Inoue, Kosei Takagi, Hidetaka Yamamoto, Shinichi Toyooka	Thoracic, Breast and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan | Center for Comprehensive Genomic Medicine, Okayama University Hospital, Okayama, Japan | Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan | Pathology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan	Molecular diagnosis of lung tumors with a history of pancreatic cancer: Spatial profiling-based differential markers and functional insights into invasive mucinous adenocarcinoma 4/21/2026 9:00:00 AM | Digital Pathology 3 Open abstract	GeoMx
4951	Sanha Hwang	Seoul National University, Seoul, Korea, Republic of	Unraveling the role of APOE/APOC1/SPP1/TREM2‑positive lipid‑Associated macrophages in destructive venous invasion and metastasis of colorectal cancer 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	Xenium; GeoMx
4970	Mohamed M. Haq, Curtis Benson, Meik Kunz, Elim Cheung	HCA Houston Healthcare Southeast, Pasadena, TX | The Bioinformatics CRO, Sanford, FL | BioChain Institute Inc., Newark, CA	Transcriptomic analysis reveals myoepithelial cell reprogramming in invasive breast cancer 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	GeoMx
4971	Chia-Ying Lee, Arya Bahrami, Yi Cui, Megan Vandenberg, Michael McKenna, Shanshan He, Mirko Corselli, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA	Integrated spatial multiomic mapping of glioblastoma microenvironments via proteomic and transcriptomic profiling 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	GeoMx
4972	Jean-Philippe Guegan, Jean-Michel Coindre, Carine Ngo, Antoine Bougoüin, Christophe Rey, Catherine SAUTÈS-FRIDMAN, Wolf Herve Fridman, Armelle Dufresne, Alban Bessede, Antoine Italiano	Immunospot, Cleveland, OH | Institute Bergonié, Bordeaux, France | Carine Ngo (Individual) | Sorbonne University, Paris, France | ImmuSmol, Pessac, France | INSERM U1138 (Centre de Recherche des Cordeliers), Paris, France | Léon Bérard Center, Lyon, France | Institute Bergonié, Bordeaux cedex, France	KIT exon 9 versus exon 11 mutations imprint distinct spatial and phenotypic immune microenvironments in gastrointestinal stromal tumors 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	GeoMx
5082	Benecia Jackson, Zahra Mesrizadeh, Robert Lou, Yate-Ching Yuan, Daniel Schmolze, Rania Bakkar, Jerneja Tomsic, Cristal Resto, Nancy Sanchez, Padmashree Rida, Shankar Subramaniam, Lucio Miele, Victoria Seewaldt, Nikita Jinna	Department of Population Sciences, Beckman Research Institute of The City of Hope, Duarte, CA | UC San Diego, La Jolla, CA | Carrigent, Covina, CA | Division of Translational Bioinformatics, City of Hope Comprehensive Cancer Center, Duarte, CA | Department of Pathology, City of Hope Comprehensive Cancer Center, Duarte, CA | Department of Science, Rowland Hall, Salt Lake City, UT | Departments of Cellular & Molecular Medicine, Computer Science & Engineering, and Data Science, University of California San Diego, La Jolla, CA | LSU Health New Orleans, New Orleans, LA	Loss of androgen receptor expression in triple negative breast cancer upregulates kinesin family member C1 (KIFC1) via increased β-catenin/TCF4 signaling 4/21/2026 9:00:00 AM | Etiology and Molecular Epidemiology Approaches to Decipher Cancer Disparities Open abstract	GeoMx
6046	Giulia Petroni, Simone Romagnoli, Daniele Lavacchi, Giulia Massaro, Francesca Rizzo, Elena Alexandrova, Costanza Winchler, Alfonso Carleo, Gian Luca Grazi, Daniele Rossini, Luca Messerini, Matteo Benelli, Serena Pillozzi, Lorenzo Antonuzzo	Department of Experimental and Clinical Medicine, Università degli Studi di Firenze - UniFI (University of Florence), Firenze, Italy | Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', Università degli Studi di Firenze - UniFI (University of Florence), Firenze, Italy | Clinical Oncology Unit, Careggi University Hospital, Firenze, Italy | Department of Medicine, Surgery and Dentistry "Scuola Medica, Salernitana", University of Salerno, Salerno, Italy | Department of Experimental and Clinical Medicine, Pathology Unit, Università degli Studi di Firenze - UniFI (University of Florence), Firenze, Italy	Spatial transcriptomic profiling of cancer-associated fibroblast niches in extrahepatic cholangiocarcinoma 4/21/2026 2:00:00 PM | Fibroblasts as Architects of the Tumor Microenvironment Open abstract	GeoMx
6122	Jian Ye, Colt A. Egelston, Chongkai Wang, Marwan Fakih	Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA | Department of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, CA | City of Hope National Medical Center, Department of Medical Oncology and Therapeutics Re, CA | City of Hope National Medical Center, Duarte, CA	Organ-specific immune and metabolic programs shape spatial microenvironments in MSS colorectal cancer metastases 4/21/2026 2:00:00 PM | Metastasis and Organ-Specific Microenvironmental Evolution Open abstract	GeoMx
6470	Nakial C. W. Cross, Yael A. Day, Sonia Ndeupen, Vanessa E. Gonzalez, Zhen Miao, Sam I. Kim, Rachel M. Leskowitz, Amy Marshall, Julie K. Jadlowsky, Gabriela Plesa, Donald L. Siegel, Elizabeth O. Hexner, Jakub Svoboda, Stephen J. Schuster, Nancy R. Zhang, Joseph A. Fraietta, Andrew J. Rech, Carl H. June	Perelman School of Medicine Univ. of Pennsylvania, Philadelphia, PA | Statistics & Data Analysis, Wharton School Univ. of Pennsylvania, Philadelphia, PA	Spatial remodeling of the tumor microenvironment by IL-18-armored CD19 CAR T cells is associated with durable remission in relapsed or refractory lymphoma 4/21/2026 2:00:00 PM | Clinical Correlates of Immunotherapy Open abstract	CosMx; GeoMx
6576	Chih-Hung Chung, Han-Hsun Yu, Muh-Hwa Yang	National Yang Ming Chiao Tung University, Taipei, Taiwan	Integrative spatial transcriptomics reveals EMT-driven immune regulatory programs underlying metastasis in HNSCC 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	Xenium; Visium; GeoMx
6664	Terence C. Theisen, Alexa E. Lasley, Giang Ong, Megan Vandenberg, Brian Filanoski, Lori Hamanishi, Erin Piazza, Sayani Bhattacharjee, Courtney Anderson, Mirko Corselli, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Single-cell spatial proteomics of 1200+ protein targets in tumor microenvironments from diverse cancers using GeoMx Discovery Proteome Atlas 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	GeoMx
6684	Navneet Kaur, Wadih Issa, Ze Yu, Hua Zhong, Aleksandra Weronika Nielsen, Jay Jasti, Shahed Abdullah, Libin Yan, Damla Gunenc, Qinhan Zhou, Andrew DeVilbiss, Satwik Rajaram, Payal Kapur, Chao Xing, Liwei Jia, Andrew Z. Wang, Tian Zhang	Department of Internal Medicine (Division of Hematology-Oncology), Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX | Eugene McDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, TX | Department of Pathology, UT Southwestern Medical Center, Dallas, TX | Lyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX | Lyda Hill Department of Bioinformatics; O'Donnell School of Public Health, Eugene McDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, TX | Department of Radiation Oncology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX	Spatial multi-omics profiling of clear cell renal cell carcinoma (ccRCC) pre-and post-immunotherapy identifies new druggable targets 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	GeoMx
6749	G. Chang, D. Redwood, A. L. Koehne, M. Fitzgibbon, C. Qu, H. Yin, E. Donato, M. Lin, C. Yeung, J. J. Tiesinga, S. Thomas, L. Hsu, C. I. Li, T. K. Thomas, R. Peters, J. Huyghe; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, Alaska Native Tribal Health Consortium, Anchorage, AK, Genomics and Bioinformatics, Fred Hutchinson Cancer Center, Seattle, WA, Department of Medicine, Massachusetts General Hospital, Boston, MA		Spatial transcriptomics profiling of colorectal cancer tumors in Alaska Native peoples: Discovery of prognostic biomarkers 4/21/2026 2:35:00 PM | Spatial Biomarkers at Single-Cell Resolution: Mapping Tumor Ecosystems with Proteomics, Transcriptomics, and AI Open abstract	GeoMx
7443	Vidya Prasad Nimbalkar, Snijesh V P, Anupama CE, Mahalakshmi S, Annie Alexander, Rakesh Ramesh, Srinath BS, Jyothi S. Prabhu	Division of Molecular Medicine, St. John's Research Institute, Bangalore, India | Department of Surgical Oncology, St. John's Medical College and Hospital, Bangalore, India | Department of Surgical Oncology, Sri Shankara Cancer Hospital and Research Centre, Bangalore, India	Low hypoxia microenvironment and impaired T cell maturation drive immunotherapy resistance in premenopausal triple negative breast cancer 4/22/2026 9:00:00 AM | Microenvironmental Determinants of Therapy Response and Resistance 2 Open abstract	GeoMx

Abstract #	Authors	Affiliation	Title / Session	Products
21	Harihara Muralidharan, Cheng-Yi Chen, Friedrich Preusser, Ruben Cardenes, Kenny Workman, Hannah Le, Alfredo Andere, Lorenz Rognoni	LatchBio, San Francisco, CA | Vizgen, Cambridge, MA	AI analysis agent to accelerate end-to-end spatial biology analysis for MERSCOPE 4/19/2026 2:00:00 PM | Agentic AI in Cancer Open abstract	MerFISH
851	Davey (Cheng Zhe) Li, Michael Luo, Phuong U. Le, Maryam Safisamghabadi, Tuong V. Kieu, Andy Nkili, Paul Wambo, Rozica Bolovan, Javad Nadaf, Kevin Petrecca	Department of Neurology and Neurosurgery, Montreal Neurological Insitute-Hospital, McGill University, Montréal, QC, Canada	BMP inhibition is an effective treatment for targeting stem-like glioblastoma cell states 4/19/2026 2:00:00 PM | Stem Cell Plasticity and Lineage Reprogramming in Cancer Open abstract	MerFISH
5524	Mary Goldman, Brian Craft, Cally Lin, Jingchun Zhu, David Haussler	UC Santa Cruz Genomics Institute, Santa Cruz, CA | Stanford University, San Francisco, CA | Investigator/Distinguished Professor, Ctr. For Bio. Sci. & Eng., UC Santa Cruz, Santa Cruz, CA	Visualization and analysis of cancer genomics data using UCSC Xena 4/21/2026 2:00:00 PM | New Software Tools for Data Analysis Open abstract	Xenium; Visium; Chromium; CosMx; MerFISH
6564	Zichao Liu, Xiaofei (Sophia) Song, Jodi A. Balasi, Wei-Shen Chen, Jiang He, Justin He, Jonathan Nguyen, Carlos M. Morán-Segura, Joseph O. Johnson, Chaomei Zhang, Jane L. Messina, Zena Sayegh, Douglas C. Marchion, Sean J. Yoder, Vernon K. Sondak, Jeffrey H. Chuang, Pei-Ling Chen	The Jackson Laboratory, Farmington, CT | Moffitt Cancer Center, Tampa, FL | University of South Florida, Tampa, FL | Vizgen, Cambridge, MA | Research Scientist, Moffitt Cancer Center, Tampa, FL	Spatially resolved immunologic hallmarks of response to neoadjuvant immune checkpoint blockade in metastatic melanoma 4/21/2026 2:00:00 PM | Immune Checkpoint Blockade Open abstract	MerFISH
6673	Renchao Chen, Bin Wang, Bing Yang, Manisha Ray, Justin He, Timothy Wiggin, Lizi Maziashvili, Alexander Genshaft, Peter Reinhold, Angela Vasaturo, Jiang He	Vizgen, Cambridge, MA	MERFISH 2.0 enables high-sensitivity, customizable spatial transcriptomics for resolving immune and tumor programs in human cancers 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	MerFISH
6679	Bin Wang, Kevin Hwang, Yijia Sun, Cassandra Kysilovsky, Angela Vasaturo, Jiang He	Vizgen, Cambridge, MA	Decoding immune and tumor niches through high-plex spatial multi-omics in human cancer tissues 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	MerFISH
7440	Diego Armando Pedroza, Sung Wook Kang, Xiang H.-F. Zhang, Bora Lim, Hyun-Sung Lee, Jeffrey M. Rosen	Baylor College of Medicine, Houston, TX | UT MD Anderson Cancer Center, Houston, TX	Characterization of the metastatic TIME via spatial transcriptomics reveals unique cellular phenotypes post anti-CSF-1R and immuno-chemotherapy 4/22/2026 9:00:00 AM | Microenvironmental Determinants of Therapy Response and Resistance 2 Open abstract	MerFISH

Abstract #	Authors	Affiliation	Title / Session	Products
192	Jhe-Cyuan Guo, Yen-Lin Huang, Chia-Lang Hsu, Tsung-Che (Nathan) Wu, Chien-Huai Chuang, Ta-Chen Huang, Wen-Lun Wang, Chih-Hung Hsu	National Taiwan University Cancer Center (NTUCC), Taipei City, Taiwan | National Chung Hsing University, Taichung, Taiwan | National Taiwan University Hospital, Taipei, Taiwan | Department of Internal Medicine,E-Da Hospital/I-Shou University, Kaohsiung, Taiwan, Institute of Clinical Medicine,National Cheng Kung University Hospital, College of Medicine, Nationa, Kaohsiung City, Taiwan	Chronological evolution of immune tumor microenvironment (TME) from esophageal dysplasia (ED) to esophageal squamous cell carcinoma (ESCC) 4/19/2026 2:00:00 PM | Inflammation and Cancer Progression Open abstract	nCounter
1106	Lakshmi Chandramohan, Kirsteen Maclean, Quratul Ain, Brigitte Lovell, Lisa Duncan, Sergio Hernandez, Christina Bailey, Michael Bailey, Patrick Danaher, Wei Yang, Shanshen He, Joseph M. Beechem	NeoGenomics, Fort Myers, FL | Bruker Spatial Biology, Bothell, WA	Rapid identification of comprehensive multi-omic protein and RNA biomarkers on a single FFPE tissue section using a novel integrated nCounter® workflow 4/19/2026 2:00:00 PM | Early Detection Biomarkers 1 Open abstract	nCounter
1132	Elba Marin, Silvia Garcia-Roman, Cristina Aguado, Marta Vives, Sonia Rodríguez, Susana Muñoz, Noelia Armiger, Alejandro Martínez-Bueno, Maria Gonzalez-Cao, Ana Velasco, Serafin Morales, Reyes Roxana, Ekaterina Meshoulam, Andrés Aguilar, Clara Mayo de las Casas, Miguel Ángel Molina-Vila	Pangaea Oncology, Hospital Universitari Dexeus, Barcelona, Spain | Instituto Oncológico Dr. Rosell, Hospital Universitari Dexeus, Barcelona, Spain | Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, Spain | Hospital Universitari Arnau de Vilanova, Lleida, Spain | Instituto Oncológico Dr. Rosell, Hospital Teknon, Barcelona, Spain	Malignant effusions for cfDNA/RNA genotyping and drug testing: Turning malignant fluids into personalized cancer models 4/19/2026 2:00:00 PM | Liquid Biopsies: Circulating Nucleic Acids 1 Open abstract	nCounter
2048	Carmen M. Ortiz-Sanchez, Jarline Encarnacion, Stephanie Montalvo, Shakira Abad, Gabriela Castro, Lenin Godoy, Ralphdy Vergne, Jong Y. Park, Gilberto Ruiz-Deya	Ponce Health Sciences University, Ponce, Puerto Rico | University of Puerto Rico at Mayaguez, Mayaguez, Puerto Rico | Pontificia Universidad Católica de Puerto Rico, Ponce, Puerto Rico | Moffitt Cancer Center, Tampa, FL	Exosomal micrornas as epigenetic biomarkers of disease progression in Hispanic men with metastatic castration-resistant prostate cancer 4/20/2026 9:00:00 AM | MicroRNAs as Cancer Biomarkers, Therapeutic Targets, and Modulators of Treatment Response Open abstract	nCounter
2298	Rhitajit Sarkar, Shilpa Thakur, Gus Fridell, Elijah Edmondson, Sonam Kumari, Joanna KLUBO-GWIEZDZINSKA	Metabolic Diseases Branch, NIH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Bethesda, MD | National Institutes of Health, Bethesda, MD | Johns Hopkins University, Baltimore, MD | National Institutes of Health, Reston, VA	Spatial immune profiling reveals varying tumor microenvironments in papillary thyroid microcarcinoma 4/20/2026 9:00:00 AM | Hormone Receptor Signaling and Therapeutic Targeting Open abstract	GeoMx; nCounter
2321	Lenora W. M. Loo, Yuqing Li, Kami K. White, Jose A. Aparicio, Veronica Wendy Setiawan, Brenda Y. Hernandez, Anna H. Wu, Christopher Haiman, Loic Le Marchand, Lynne R. Wilkens, Iona Cheng	Cancer Biology Program, University of Hawai'i Cancer Center, Honolulu, HI | Department of Epidemiology and Biostatistics, School of Medicine, University of California San Francisco, San Francisco, CA | Population Sciences of the Pacific, University of Hawai'i Cancer Center, Honolulu, HI | Department of Population and Public Health Sciences, University of Southern California, Keck School of Medicine, Los Angeles, CA | USC Norris Comprehensive Cancer Center, Los Angeles, CA	Expression of 27-hydroxycholesterol metabolizing enzymes and breast cancer clinicopathological characteristics: The Multiethnic Cohort Study 4/20/2026 9:00:00 AM | Biomarkers of Endogenous or Exogenous Exposures, Early Detection, Biological Effects, and Prognosis Open abstract	nCounter
2487	Luis del Pozo Yauner, Maha Babker, Rosetta Campbell, Veronica Ramirez-Alcantara, Huseyin Kilic, Elba Turbat-Herrera, Hector Chavarria Bernal, Bahaaeldin Youssef, Ateeqa Mujeeb Ullah, Wei Yang, Guillermo A. Herrera, Ajay Pratap Singh	Pathology, University of South Alabama College of Medicine, Mobile, AL | USA Health Biobank and Histology Service, University of South Alabama College of Medicine, Mobile, AL | Bruker Spatial Biology, Seattle, WA | SOM-Cell and Molecular Biology, School of Medicine at the University of Mississippi Medical Center, Jackson, MS	Integrating clinical and multiomics data to characterize ethnic disparities in breast cancer on the gulf coast 4/20/2026 9:00:00 AM | Community-Engaged Approaches to Equity Across the Cancer Journey: From Prevention to Trial Design Open abstract	nCounter
2490	Ritam Adhikari, Chiranjeev Dash, Rabindra Roy	The Quarry Lane School, Dublin, CA | Dept. of Oncology, Georgetown Lombardi Comp. Cancer Center, Washington | Georgetown Lombardi Comprehensive Cancer Ctr., Washington	Systemic molecular disparities in Black vs. White breast cancer survivors: Beyond socioeconomic determinants 4/20/2026 9:00:00 AM | Community-Engaged Approaches to Equity Across the Cancer Journey: From Prevention to Trial Design Open abstract	nCounter
2905	Maksymilian Jan Pilecki, Shannon M. Wallet, Robert Maile, Gerik Tushoski- Alemán, Song Han, Steven J. Hughes	Department of Surgery, University of Florida College of Medicine, Gainesville, FL	Pancreatic adenocarcinoma immune tumor microenvironment is shaped by differential miRNA expression 4/20/2026 2:00:00 PM | Modifiers of Inflammation and the Tumor Microenvironment Open abstract	nCounter
3299	Tat San Lau, Yi Shun Wong, Maciej Jakub Trybull, Kit Ying Loucia Chan, Ho Sze Jacqueline Lee, Chi Chiu Wang, Joseph Kwong	Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, Hong Kong | School of Medicine, Keele University, Keele, United Kingdom	Autocrine lymphotoxin signalling promotes ovarian tumor growth through CD74 4/20/2026 2:00:00 PM | RTK-ERBB-PI3K and New Targets in Therapeutic Resistance Open abstract	nCounter
4323	Colette R. Worcester, Amrita Mitra, Harsh B. Pathak, Shane R. Stecklein	Cancer Biology, University of Kansas Medical Center, Kansas City, KS | Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS | Radiation Oncology, Orlando Health Cancer Institute, Orlando, FL	The SPHK2 inhibitor opaganib potentiates tumor-intrinsic STING activation in triple-negative breast cancer in vitro 4/21/2026 9:00:00 AM | Immunomodulatory Agents Open abstract	nCounter
4795	Michael Emilio Patrick, Wei Yang, Liang Zhang, Isabel Lee, Stefan-Laural Rogers, Shanshan He, Christina Bailey, John Lyssand, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA	Investigating HER2+ tumor cell motility and angiogenesis in FFPE breast cancer in space and at scale with CosMx and nCounter multiomics 4/21/2026 9:00:00 AM | Angiogenesis Open abstract	CosMx; nCounter
6549	Yi Cui, Moumita Nath, Michael Emilio Patrick, Claire Williams, Daniel McGuire, Jobin K. Paul, Kowshik Jaganathan, Biswajit Das, Mohit Malhotra, Shanshan He, Joseph M. Beechem, Satish Sankaran	Bruker Spatial Biology, Seattle, WA | Farcast Biosciences India, Bengaluru, India	Integrating functional biosignatures and same-cell spatial multiomics to predict synergistic benefit of combination checkpoint therapy in head and neck cancer 4/21/2026 2:00:00 PM | Immune Checkpoint Blockade Open abstract	CosMx; nCounter
6674	Lakshmi Chandramohan, Kirsteen Maclean, Sergio Hernandez, Brigitte Lovell, Courtney Todorov, Harry Nunns, Jiong Fei, Judy Kuo, Erinn A. Parnell, Qingyan Au	NeoGenomics, Fort Myers, FL	Metabolic reprogramming in advanced renal tumors contributes to a dysfunctional immune response and immune exhaustion within the tumor microenvironment 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	nCounter
7311	LUIS DEL POZO-YAUNER, Veronica Ramirez-Alcantara, Elba A. Turbat-Herrera, Hector Chavarria Bernal, Maha Babker, Huseyin Kilic, Rosetta Campbell, Bahaaeldin Youssef, Ajay Singh, Julio Isael Perez-Carreon, Wei Yang, Guillermo A. Herrera	Pathology, University of South Alabama College of Medicine, Mobile, AL | USA Health Mitchell Cancer Institute, Mobile, AL | University of South Alabama College of Medicine, Mobile, AL | SOM-Cell and Molecular Biology, University of Mississippi Medical Center and Cancer Center and Research Institute, Jackson, MS | National Institute of Genomic Medicine, Mexico City, Mexico | Bruker Spatial Biology, Seattle, WA	Characterization of PERK-positive polyploid-like breast cancer cells and their association with unfolded protein response signatures 4/22/2026 9:00:00 AM | Hypoxic and Proteotoxic Stress Response Open abstract	nCounter
7422	Tsung-Hao Liu, Li-Chun Lu, Yu-Yun Shao, Shu-Han Yang, Chi-Yuan Yao, Chia-Lang Hsu, Ying-Chun Shen, Ann-Lii A. Cheng, Chih-Hung Hsu	National Taiwan University Hospital, Taipei, Taiwan | National Taiwan University, Taipei, Taiwan | Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan | National Taiwan University Cancer Center (NTUCC), Taipei, Taiwan | Professor, Dept. of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan	Investigation of acquired resistance to atezolizumab-bevacizumab in hepatocellular carcinoma: Paired tumor microenvironment analysis in a mouse model and human subjects 4/22/2026 9:00:00 AM | Microenvironmental Determinants of Therapy Response and Resistance 2 Open abstract	nCounter
7606	Li Feng, Amber N. Hurson, Shahin Sayed, Hela Koka, Viviane Oluoch, Veronica Ngundo, Alfred Mburu Githuka, Zaitun Ajuoga, Shaoqi Fan, Kristine Jones, Belynda Hicks, Amy Hutchinson, Maria Brown, Petra Lenz, Aaron M. Rozeboom, Difei Wang, Francis Makokha, Stefan Ambs, Jonine D. Figueroa, Ruth M. Pfeiffer, Xiaohong Rose Yang	Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD | Aga Khan University Hospital, Nairobi, Kenya | Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD | Mount Kenya University, Nairobi, Kenya | Center for Cancer Research, National Cancer Institute, Bethesda, MD	Tumor and Host Determinants of the Breast Tumor Immune Microenvironment in Kenyan Breast Cancer Women 4/22/2026 9:00:00 AM | Risk Prediction Modeling, Screening, Early Detection, and Preneoplastic and Tumor Markers Open abstract	nCounter
7661	Brian Filanoski, Lori Hamanishi, Giang Ong, Terence C. Theisen, Erin Piazza, Christina Bailey, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Integrated multiomics profiling of lysates using nCounter® protein and RNA panels for comprehensive oncology insights 4/22/2026 9:00:00 AM | Multi-Omics, Systems Biology, and Biological Mass Spectrometry Open abstract	nCounter
7665	Giang Ong, Terence C. Theisen, Brian Filanoski, Lori Hamanishi, Erin Piazza, Christina Bailey, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Multi-step antibody validation for nCounter high-plex multiomics panels 4/22/2026 9:00:00 AM | Multi-Omics, Systems Biology, and Biological Mass Spectrometry Open abstract	nCounter
7907	Barbara Cardinali, Alice Stella, Chiara Molinelli, Marco Bruzzone, Yanina Lizet Castillo, Francesca Pitto, Barbara Massa, Simona Pigozzi, Andrea Sciutto, Giorgia Anselmi, Maria Dono, Virna Maltoni, Benedetta Conte, Giulia Buzzatti, Davide Soldato, Gaia Griguolo, Valentina Guarneri, Mario Giuliano, Caterina Marchiò, Fabio Puglisi, Lorenzo Gerratana, Francesca Poggio, Lucia Del Mastro	IRCCS Ospedale Policlinico San Martino, Genova, Italy | University of Genova, Genova, Italy | University of Piemonte Orientale, Novara, Italy | Institute of Oncology IOV-IRCCS, Padova, Italy | University of Naples "Federico II", Naples, Italy | FPO Istituto Candiolo (IRCCS), Candiolo, Italy | Centro di Riferimento Oncologico IRCCS, Aviano, Italy	Genomic, immune, and clinical characterization of estrogen receptor-positive, HER2-low breast cancer: The NextGIM trial latest updates 4/22/2026 9:00:00 AM | Translational Biomarkers and Emerging Molecular Approaches Open abstract	nCounter

Abstract #	Authors	Affiliation	Title / Session	Products
806	Yesul Jeong, Se Jun Park, Sung Hak Lee*, Younghoon Kim*	Department of Hospital Pathology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of | Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul, Korea, Republic of | Department of Hospital Pathology, Seoul St. Mary’s Hospital, Seoul, Korea, Republic of	Tumor microenvironment of ampulla of Vater cancer reveals distinct spatial niche of CAF, TIL, and TAM and their correlation with clinicopathologic features 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	CellScape
3973	Tim Schunk, Tim Mandelkow, Shida Xiong, Jonas Raedler, Rodler Severin, Philipp Nuhn, Anne Letsch, Marion van Macklenbergh, Jan Weitkamp, Jakob Kohler, Arne Christians, Oliver Braubach, Steve Lott, Micaela Mathiak, Gavin Gordon, Björn Konukiewitz, Christoph Rocken, Niclas Christian Blessin	Universitätsklinikum Schleswig-Holstein, Kiel, Germany | Bruker Spatial Biology | Canopy Biosciences, St. Louis, CA | Bruker Spatial Biology, St. Louis, CA | Professor, Dept. of Pathology, Christian-Albrechts-University, Kiel, Germany	A framework for antibody validation via spatial proteo-transcriptomics using the CellScape platform 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx; CellScape
6591	Daniel Jimenez-Sanchez, Matthew H. Ingalls, Sanghamithra korukonda, Brian J. Lane, Isabella Marie Peshek, Patrick Danaher, Prajan Divakar, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO | Bruker Spatial Biology, Seattle, WA | Division of Gastroenterology, Northwestern University, Chicago, IL	Cross platform same slide multi-omics reveals Treg heterogeneity and links to spatial niche variability in pre-cancerous colonic inflammation 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	CosMx; CellScape
6660	Daniel Jimenez-Sanchez, Brian J. Lane, Matthew H. Ingalls, Charles Eldon Jackson, Steven T. Lott, Adam Northcutt, Arne Christians, Anke Brix, Jennifer Brooks, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO | Bruker Spatial Biology, Hanover, Germany	CellScape Quality Control (CSQC): A tissue- and protein-agnostic platform for spatial proteomics quality assessment 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	CellScape
6672	Thore Boettke, Jannik Boog, Charles Eldon Jackson, Matthew H. Ingalls, Arne Christians, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO	Expanding the boundaries of spatial proteomics with a universal antibody labeling strategy and EpicIF™ multiplexing chemistry 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	CellScape
6678	Arne Christians, Thore Boettke, Jannik Boog, Charles Eldon Jackson, Matt Ingalls, Brian J. Lane, Daniel Jimenez Sanchez, Christoph Rocken, Niclas Christian Blessin, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO | Dept. of Pathology, University Medical Center Schleswig-Holstein, Kiel, Germany	Ultra-high-plex immunofluorescence analysis of the tumor-immune microenvironment with EpicIF technology on the CellScape platform 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	CellScape

Abstract #	Authors	Affiliation	Title / Session	Products
789	Shyamtanu Chattoraj, Pamela Flatley, Stacy Elliott, David Castillo, Kenny Chung, Doug Werner, Jude Dunne, Huy Nguyen	Research and Development, Bruker Spatial Genomics, San Jose, CA	PaintScapeTM enables in situ, single cell spatial multiomic visualization of 3D genome organization in fresh frozen colorectal carcinoma tissue in spatially resolved tissue microenvironments 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	PaintScape
6201	Matija Snuderl, Yuxiu Wang, Neha Dhasmana, Pamela Flatley, Stacy Elliott, Douglas Werner, Jude Dunne, Huy Nguyen, Shyamtanu Chattoraj	NYU Langone Health, New York, NY | Bruker Spatial Genomics, San Jose, CA	PaintScapeTM enables multiomic in-situ direct visualization of spatial 3D genome architecture of single cells in intact fresh frozen Glioblastoma tissue in native tumor microenvironments 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	PaintScape
7235	Yi Cui, Huy Nguyen, Andrea Floris, David King, Serdar Tulu, David Castillo, Shanshan He, Shyamtanu Chattoraj, Jude Dunne, Mirko Corselli, John Lyssand, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA | Bruker Spatial Genomics, San Jose, CA	Integrated spatial multiomic profiling of 3D genome architecture and transcriptome-wide gene expression in breast cancer models 4/22/2026 9:00:00 AM | Chromatin Architecture and Regulatory Landscapes Open abstract	CosMx; PaintScape
7243	Huy Nguyen, Sophie Pribus, Zhicheng Ma, David King, Johnson Huynh, Serdar Tulu, Marc Glazer, Brian Smart, David Castillo, Kenny Chung, Shyamtanu Chattoraj, Jude Dunne, Doug Werner, Christina Curtis, Mark Munch	Bruker Spatial Genomics, San Jose, CA | Stanford University, Stanford, CA	In-situ direct single-cell visualization of 3D genome architecture in ER+ and HER2+ breast cancer cell lines using PaintScapeTM system 4/22/2026 9:00:00 AM | Chromatin Architecture and Regulatory Landscapes Open abstract	PaintScape

Abstract #	Authors	Affiliation	Title / Session	Products
70	Jiwoon Park, Ryan Shultzaberger, Braulio Banuelos, McKenzie Pavlich, Sabrina Shore, Daan Witters, Kyung-A Kim, Taeyul K. Kim, Minsun Jung, Han Sang Kim, Christopher E. Mason	Weill Cornell Medicine, New York, NY | Singular Genomics, San Diego, CA | Yonsei University, Seoul, Korea, Republic of	SPOT-Met: Spatially decoding organotropism and immunotherapy response in colorectal cancer from 1,000 multi-omic tumors 4/19/2026 2:00:00 PM | Digital Pathology 1 Open abstract	G4X
1201	Yunhe Liu, Idania Carolina Lubo Julio, Wei Lu, Alejandra G. Serrano, Jean R. Clemenceau, Amber Famiglietti, Karen Colbert, Yibo Dai, Yang Liu, Jun Wang, Jeremy L. Davis, Mingyao Li, Paul F. Mansfield, Tae Hyun Hwang, Luisa M. Solis-Soto, Linghua Wang	Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX | Department of Surgery, Vanderbilt University Medical Center, Nashville, TN | National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD | Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX | BioChemistry&Molecular Biology, University of Maryland School of Medicine, Baltimore, MD | University of Pennsylvania, Philadelphia, PA | Vice President, Acute Care Services, UT MD Anderson Cancer Ctr., Houston, TX | Department of Translational Molecular Pathology, the university of MD Anderson cancer center, Houston, TX	Spatial 3D and multi-omics mapping of diffuse gastric cancer evolution from preinvasive to invasive lesions in CDH1 mutation carriers 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	Xenium; Visium; CosMx; GeoMx; G4X
2201	Maria Moozhiyil Korah, James P. Agolia, Biren Reddy, Renceh A. B. Flojo, Amanda Gonçalves, Lilin Wang, Rosyli F. Reveron-Thornton, Chuner Guo, Beatrice Sun, Amanda R. Kirane, George Poultsides, Deshka Foster, R. Stephanie Huang, Gregory W. Charville, Michael T. Longaker, Daniel Delitto	Stanford University, Stanford, CA | University of Minnesota, Minneapolis, MN | Asst. Professor, Dept. of Medicine, University of Minnesota, Minneapolis, MN	Multidimensional transcriptomic alas of recurrent uterine leiomyosarcomas uncovers stem-like hormonal cells with high drug sensitivity and improved patient outcomes 4/20/2026 9:00:00 AM | Metabolic and Transcriptional Control of Cancer Stem Cell Plasticity Open abstract	G4X
2222	James P. Agolia, Chuner Guo, Rosyli F. Reveron-Thornton, Xiaomo Li, Maria Moozhiyil Korah, Angela Tabora, Byrne Lee, Amanda R. Kirane, George Poultsides, Brendan Visser, Gregory W. Charville, Michael T. Longaker, Deshka S. Foster, Daniel Delitto	Surgery, Stanford University, Stanford, CA | Pathology, Stanford University, Stanford, CA	Mapping lymphoid responses to tumor growth and lymph node metastasis: multiomic spatial analysis of pancreatic ductal adenocarcinoma reveals tertiary lymph node structures 4/20/2026 9:00:00 AM | Tertiary Lymphoid Structures in Cancer Open abstract	G4X
2254	Eric Sha, Seock-Jin Chung, Jean R. Clemenceau, Sunho Park, Minji Kim, Inyeop Jang, Youngwon Cho, Seunghyi Kook, Soonyoung Lee, Jongseong Jang, Eunyoung Choi, Tae Hyun Hwang	Vanderbilt University, Nashville, TN | Vanderbilt University Medical Center, Nashville, TN | LG AI Research, Seoul, Korea, Republic of	3D multimodal spatial profiling of pre-gastric cancer progression using same-slide RNA-protein and fluorescent H&E 4/20/2026 9:00:00 AM | Tumorigenesis and Early Microenvironmental Trajectories Open abstract	G4X
4179	Inyeop Jang, Soyoung Im, Minji Kim, Seok-Jin Chung, Minsoo Lee, Soonyoung Lee, Jongseong Jang, Tae Hyun Hwang	Vanderbilt University Medical Center, Nashville, TN | LG AI Research, Seoul, Korea, Republic of	Three-dimensional spatial multi-omics of gastric tumor sections reveal hidden features beyond 2D analyses 4/21/2026 9:00:00 AM | Integrative Computational Approaches 2 Open abstract	G4X
4218	Minji Kim, Sunho Park, Seock-Jin Chung, Inyeop Jang, Jean R. Clemenceau, Soyoung Im, Eric Sha, Hwanil Choi, Soonyoung Lee, Jongseong Jang, Sam C. Wang, Tae Hyun Hwang	Section Surgical Research, Vanderbilt University Medical Center, Nashville, TN | Surgical Section Research, Vanderbilt University Medical Center, Nashville, TN | College of medicine, The Catholic University, Suwon, Korea, Republic of | LG AI Research, Seoul, Korea, Republic of | University of Texas Southwestern Medical Center, Dallas, TX	ProteoBridge: Bridging skipped sections via histology-based protein prediction 4/21/2026 9:00:00 AM | Machine Learning Approaches for Cancer Prediction Open abstract	G4X
4235	I-Chuang Liao, Minh-Khang Le, Vivek Pujara, Haley Jun, Devanshi Pratiher, Jane C. Figueiredo, Nathalie Nguyen, Chintda Santiskulvong, Angie Laguna, Yi Zhang, Keluo Yao, Joshua Jay Levy	Cedars-Sinai Medical Center, Los Angeles, CA | Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA	Cell-level spatial transcriptomics detection of microenvironmental STAT1-expressing plasma cells in colorectal cancer recurrence by G4X 4/21/2026 9:00:00 AM | Adaptive Immunity in Cancer Open abstract	G4X
6202	Biren Reddy, Maria Korah, James P. Agolia, Rosyli Reveron-Thornton, Maggie Lam, Deshka Foster, Michael T. Longaker, Daniel Delitto	Stanford University, Stanford, CA	Integrated multiomic atlas of pancreatic solid pseudopapillary neoplasms suggests acinar cells as a potential cell-of-origin 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	G4X
6685	Michael Lawson, Kenneth Gouin, Sabrina Shore, Yuji Ishitsuka, Richard Que, Eli Glezer, Daan Witters	Singular Genomics, San Diego, CA | Singular Genomics, LA JOLLA, CA	Integrated high-throughput multimodal spatial profiling of RNA, protein, and morphology in FFPE sections with the G4X™ Spatial Sequencer 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	G4X
6686	Michael Lawson, Tung T. Le, Ryan Shultzaberger, Ashley Tsue, Zane Hiatt, Nathan Ing, Kenneth Gouin, Eli Glezer, Daan Witters	Singular Genomics, San Diego, CA | Singular Genomics, LA JOLLA, CA	Direct-Seq™ enables spatially resolved in situ sequencing of IgH and TCRβ transcripts in FFPE tissue at subcellular resolution 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	G4X
6890	Jean R. Clemenceau, Yunhe Liu, Idania Carolina Lubo Julio, Soyoung Im, Seock-Jin Chung, Sam C. Wang, Paul F. Mansfield, Luisa Maren Solis Soto, Linghua Wang, Tae Hyun Hwang	Section of Surgical Research, Vanderbilt University Medical Center, Nashville, TN | UT MD Anderson Cancer Center, Houston, TX | Department of Translational Molecular Pathology, UT MD Anderson Cancer Center, Houston, TX | Department of Pathology, The Catholic University of Korea St. Vincent's Hospital, Suwon, Korea, Republic of | Department of Surgery, UT Southwestern Medical Center, Dallas, TX | Department of Surgical Oncology, UT MD Anderson Cancer Center, Houston, TX	Subcellular 3D multi-omic models of CDH1-mutant diffuse gastric cancer improve recapitulation of tumor microenvironment structure and reveal precancer signature niches 4/22/2026 9:00:00 AM | New Algorithms and Computational Methods Open abstract	G4X

Abstract #	Authors	Affiliation	Title / Session	Products
478	Marie-Claire Phélipot, Eric Chabrol, Julie Lichière, Alice Aymard, alexandre Baagnolini, Nadjiba Marès, Cécile Lemoigne, Matthieu Tassa, Sophie Mesnard, Caroline Huber, Ester Morgado, Marion Seillier, Jacques Fieschi	Mimabs, Marseille, France	Implementation of single B-cell screening to select antibodies in one day based on affinity and multiple binding properties 4/19/2026 2:00:00 PM | RNA, Gene and Cell Therapies, and Enabling Assay Technologies Open abstract	Beacon
4403	Eric Chabrol, Marie-Claire Phélipot, Cécile Lemoigne, Julie Lichière, Nadjiba Marès, Alice Aymard, Alexandre Bagnolini, Sophie Mesnard, Caroline Huber, Matthieu Tassa, Ester Morgado, Jacques Fieschi	Mimabs, Marseille, France	A fast and robust development process providing new highly internalized anti-hHER2 antibody-drug conjugates 4/21/2026 9:00:00 AM | Antibody Technologies and Platforms 2 Open abstract	Beacon
4984	Joseph Zenga, Musaddiq Awan, Fumou Sun, Stuart J. Wong, Abdullah Memon, Tyce Kearl, Ean Norenberg, Margaret L. Hoang, Joseph M. Beechem, Eric Hobbs, Ashley Heck, Rachel Liu, Daniel McGuire, Erin Piazza, Peiman Hematti, Heather Himburg	Medical College of Wisconsin, Milwaukee, WI | Bruker Spatial Biology, Seattle, WA | Bruker Spatial Biology, Piedmont, CA | Bruker Cellular Analysis, Emeryville, CA	Dissociative, spatial, and functional single-cell profiling reveals antigen-driven exhaustion and chemotactic failure of tumor-reactive T cells in HPV-negative HNSCC 4/21/2026 9:00:00 AM | Tumor-Immune Crosstalk Open abstract	CosMx; Beacon

Abstract #	Authors	Affiliation	Title / Session	Products
65	Luke McNickle, Assya Legrini, Yoana Doncheva, Mari-Claire McGuigan, Ghazal Latifi, Claire Kennedy Dietrich, Molly McKenzie, Phimmada Hatthakarnkul, Tom Wright, Leonor Patricia Schubert Santana, Emma McCargow, Cong Chen, Henry M. Wood, Jon Laye, Gemma Hemmings, Caroline Cartlidge, Derek Magee, Phil Quirke, Joanne Edwards, Nigel Jamieson	School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom | Genomics England Limited, London, United Kingdom | Division of Pathology and Data Analytics, University of Leeds, Leeds, United Kingdom | School of Computer Science, University of Leeds, Leeds, United Kingdom	Integrating spatial transcriptomics and digital pathology with whole-genome data from Genomics England to characterise the tumour and it's microenvironment in colorectal cancer 4/19/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 1 Open abstract	CosMx
478	Marie-Claire Phélipot, Eric Chabrol, Julie Lichière, Alice Aymard, alexandre Baagnolini, Nadjiba Marès, Cécile Lemoigne, Matthieu Tassa, Sophie Mesnard, Caroline Huber, Ester Morgado, Marion Seillier, Jacques Fieschi	Mimabs, Marseille, France	Implementation of single B-cell screening to select antibodies in one day based on affinity and multiple binding properties 4/19/2026 2:00:00 PM | RNA, Gene and Cell Therapies, and Enabling Assay Technologies Open abstract	Beacon
622	Alexandra Prosser-Dombrowski, Irina Pushel, Priyanka Prem Kumar, Thomas Gremminger, Michaella Rekowski, Midhat S. Farooqi, Michael Washburn, Jay L. Vivian, John M. Perry	Children's Mercy Kansas City, Kansas City, MO | The University of Kansas Medical Center, Kansas City, MO | Children's Mercy Research Institute, Kansas City, MO	Infant KMT2A::AFF1 acute lymphoblastic leukemia stem cell model reveals early impact on the proteome 4/19/2026 2:00:00 PM | Developmental Origins, Drivers, and Heterogeneity in Pediatric Cancer Open abstract	-
687	Amanda Lindberg, Bartosz Sobocki, Patrick Micke, Carina Strell	Immunology, genetics and pathology, Uppsala University, Uppsala, Sweden | Department of Oncology and Radiotherapy, Medical University of Gdańsk, Gdańsk, Poland	In situ KRAS-mapping and spatial -omics characterization in lung premalignancy 4/19/2026 2:00:00 PM | Methods to Measure Tumor Evolution and Heterogeneity Open abstract	CosMx
718	Janny Kim, Noha Sinno, Michael Milosevic, Catherine Coolens	University of Toronto, Toronto, ON, Canada | Princess Margaret Cancer Centre, Toronto, ON, Canada	Novel characterization of tumor transport dynamics using Cross-Voxel eXchange Model and DCE-MRI 4/19/2026 2:00:00 PM | Molecular Pathology Open abstract	-
789	Shyamtanu Chattoraj, Pamela Flatley, Stacy Elliott, David Castillo, Kenny Chung, Doug Werner, Jude Dunne, Huy Nguyen	Research and Development, Bruker Spatial Genomics, San Jose, CA	PaintScapeTM enables in situ, single cell spatial multiomic visualization of 3D genome organization in fresh frozen colorectal carcinoma tissue in spatially resolved tissue microenvironments 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	PaintScape
805	Adele-Asia Ponzoni, Evangelos Liapis, Lea Anne T. Maristela, Elizabeth E. Ginalis, Linda Szymanski, Kar Fai Chow, Kangmin Lee, George J. Kaptain, Claire L. Carter	Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ | Department of Neurosurgery, Rutgers New Jersey Medical School, Newark, NJ | Department of Pathology, Hackensack University Medical Center, Hackensack, NJ | Biorepository, Hackensack University Medical Center, Hackensack, NJ | Department of Neurosurgery, Hackensack University Medical Center, Hackensack, NJ | Department of Pathology, Hackensack Meridian School of Medicine, Nutley, NJ	Fluorescence-guided multi-sampling and spatial multi-omics reveal functional lipid vulnerabilities in glioblastoma 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	-
808	Margaret L. Hoang, Rachel Liu, Dan McGuire, Ashley Heck, Kimberly Young, Megan Vandenberg, Claire Williams, Martin Shelton, Prajan Divakar, Patrick Danaher, Erin Piazza, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Single cell spatial multiomics of TCR and BCR repertoires using CosMx® SMI to characterize immune cell dynamics in PBMCs and tumors 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	CosMx
809	Yi Cui, Claire Williams, Chia-Ying Lee, Chi Phan, Sierra Mckinzie, Shanshan He, Ashley Heck, Kimberley Young, Lidan Wu, John Lyssand, PRAJAN DIVAKAR, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA	Spatially resolved multiomics profiling of glioblastoma reveals molecular signatures of neuropathology and immuno-oncology architecture using CosMx SMI 4/19/2026 2:00:00 PM | Spatial Protein Profiling and Multi-Modal Mapping of Tumor and Circulating Ecosystems Open abstract	CosMx
1106	Lakshmi Chandramohan, Kirsteen Maclean, Quratul Ain, Brigitte Lovell, Lisa Duncan, Sergio Hernandez, Christina Bailey, Michael Bailey, Patrick Danaher, Wei Yang, Shanshen He, Joseph M. Beechem	NeoGenomics, Fort Myers, FL | Bruker Spatial Biology, Bothell, WA	Rapid identification of comprehensive multi-omic protein and RNA biomarkers on a single FFPE tissue section using a novel integrated nCounter® workflow 4/19/2026 2:00:00 PM | Early Detection Biomarkers 1 Open abstract	nCounter
1169	Irina Pushel, Thomas Gremminger, Lisa Lansdon, Michaella Rekowski, Midhat S. Farooqi, Michael Washburn, Keith August	Children's Mercy Kansas City, Kansas City, MO | University of Kansas Medical Center, Kansas City, KS	Global proteomic analysis of pediatric T-cell acute lymphoblastic leukemia patient samples reveals distinct protein upregulation signature 4/19/2026 2:00:00 PM | Mechanistic Insights for Targeted Therapies in Pediatric Cancer Open abstract	-
1214	Mengwei Hu, Yi Cui, Qianhui Huang, Khoi Chu, Sierra McKinzie, Michael Patrick, Sharanya Iyengar, Maerjianghan Abuduli, Marianne Spatz, Nandita Joshi, Brendan Miller, Shams Vellarikkal, Timothy Riordan, Danny Bitton, Jan Lubojacky, Iya Khalil, Federica Piccioni, Michael Rhodes, Alex Tamburino, Shanshan He, Joseph Beechem, Vanessa Peterson	Merck & Co., Inc, Cambridge, MA | Bruker Spatial Biology, Seattle, WA | MSD, Prague, Czech Republic	SPACE: Spatially resolved multiomic analysis for high-throughput CRISPR screening in 3D models 4/19/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 1 Open abstract	-
1476	Steven Yan, Limin Jiang, Yan Guo	University of Miami Miller School of Medicine, Miami, FL | University of Miami, Miami, FL	Improve spatial transcriptomic data with integrated hybrid transformer and graph convolutional networks 4/20/2026 9:00:00 AM | Integrative Computational Approaches 1 Open abstract	Xenium; Visium; CosMx
2044	Rachel Liu, Joe Phan, Rustem Khafizov, Kimberly Young, Ashley Heck, Dwayne Dunaway, Sayani Bhattacharjee, Courtney Anderson, Mirko Corselli, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Single-cell spatial profiling microRNA in human colon cancer tissue using high-plex multiomic Spatial Molecular Imaging (SMI) 4/20/2026 9:00:00 AM | MicroRNAs as Cancer Biomarkers, Therapeutic Targets, and Modulators of Treatment Response Open abstract	CosMx
2207	Rachel B. Sidebottom, Antonia E. Sajche Sapon, Yamhilette Licon-Munoz, Christian A. Bowers, Sara G.m. Piccirillo	Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM | Neurosurgery, University of New Mexico Health Sciences Center, Albuquerque, NM	The impact of tumor treating fields (TTFields) on the transcriptome and the secretome of cancer stem-like cells isolated from the sub-ventricular zone of glioblastoma patients 4/20/2026 9:00:00 AM | Metabolic and Transcriptional Control of Cancer Stem Cell Plasticity Open abstract	-
2298	Rhitajit Sarkar, Shilpa Thakur, Gus Fridell, Elijah Edmondson, Sonam Kumari, Joanna KLUBO-GWIEZDZINSKA	Metabolic Diseases Branch, NIH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Bethesda, MD | National Institutes of Health, Bethesda, MD | Johns Hopkins University, Baltimore, MD | National Institutes of Health, Reston, VA	Spatial immune profiling reveals varying tumor microenvironments in papillary thyroid microcarcinoma 4/20/2026 9:00:00 AM | Hormone Receptor Signaling and Therapeutic Targeting Open abstract	GeoMx; nCounter
2487	Luis del Pozo Yauner, Maha Babker, Rosetta Campbell, Veronica Ramirez-Alcantara, Huseyin Kilic, Elba Turbat-Herrera, Hector Chavarria Bernal, Bahaaeldin Youssef, Ateeqa Mujeeb Ullah, Wei Yang, Guillermo A. Herrera, Ajay Pratap Singh	Pathology, University of South Alabama College of Medicine, Mobile, AL | USA Health Biobank and Histology Service, University of South Alabama College of Medicine, Mobile, AL | Bruker Spatial Biology, Seattle, WA | SOM-Cell and Molecular Biology, School of Medicine at the University of Mississippi Medical Center, Jackson, MS	Integrating clinical and multiomics data to characterize ethnic disparities in breast cancer on the gulf coast 4/20/2026 9:00:00 AM | Community-Engaged Approaches to Equity Across the Cancer Journey: From Prevention to Trial Design Open abstract	nCounter
2687	Mari-Claire McGuigan, Luke McNickle, Assya Legrini, Ghazal Latifi, Claire Kennedy-Dietrich, Hannah Morgan, Olivia McCabe, Fraser Duthie, Tengyu Zhang, Michail Doukas, Andrea Gonzelz Cisar, Yoana Doncheva, Josefina Martinez Vasquez, Yi Cui, Sanghamithra korukonda, Ashley Heck, Kim Young, Joanne Edwards, Joseph Beechem, Nigel Jamieson	Jamieson Spatial Laboratory, The University of Glasgow, Glasgow, United Kingdom | Glasgow Tissue Research Facility, The University of Glasgow, Glasgow, United Kingdom | Department of Pathology, The Queen Elizabeth University Hospital, Glasgow, United Kingdom | Pathology and Clinical Bioinformatics, Erasmus MC, Rotterdam, Netherlands | R&D, Bruker Spatial Biology, Seattle, WA | Translational Cancer Pathology (Edwards Lab), The University of Glasgow, Glasgow, United Kingdom	First single slide spatially resolved multiomic integration of pancreatic cancer: High-plex proteomic and whole transcriptome analysis 4/20/2026 2:00:00 PM | Application of Bioinformatics to Cancer Biology 3 Open abstract	CosMx
2757	Evelyn R. Metzger, Patrick Danaher, Nicole Ortogero, Sayani Bhattacharjee, Prajan Divakar, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA | Bruker Spatial Biology, Piedmont, CA	Scale meets Speed: A transcriptome-wide spatial analysis that runs a rapid and interactive hypothesis-driven workflow with AtoMx® SIP 4/20/2026 2:00:00 PM | Large Language Models in the Clinic Open abstract	-
3951	Assya Legrini, Tengyu Zhang, Mari-Claire McGuigan, Colin Wood, Luke McNickle, Claire Kennedy-Dietrich, Ghazal Latifi, Yoana Doncheva, Josefina Vasquez, Hannah Morgan, Pamela McCall, Michail Doukas, Joanne Edwards, Nigel Jamieson	Univ. of Glasgow, Glasgow, United Kingdom | Glasgow Tissue Research Facility, Univ. of Glasgow, Glasgow, United Kingdom | Erasmus MC, Rotterdam, Netherlands	Spatial mapping of B7-H3 mediated cellular plasticity in treatment naive pancreatic cancer 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx; GeoMx
3973	Tim Schunk, Tim Mandelkow, Shida Xiong, Jonas Raedler, Rodler Severin, Philipp Nuhn, Anne Letsch, Marion van Macklenbergh, Jan Weitkamp, Jakob Kohler, Arne Christians, Oliver Braubach, Steve Lott, Micaela Mathiak, Gavin Gordon, Björn Konukiewitz, Christoph Rocken, Niclas Christian Blessin	Universitätsklinikum Schleswig-Holstein, Kiel, Germany | Bruker Spatial Biology | Canopy Biosciences, St. Louis, CA | Bruker Spatial Biology, St. Louis, CA | Professor, Dept. of Pathology, Christian-Albrechts-University, Kiel, Germany	A framework for antibody validation via spatial proteo-transcriptomics using the CellScape platform 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx; CellScape
3974	Claire Williams, Patrick Danaher, Megan Vandenberg, Martin Shelton, Mirko Corselli, Christine Kang, John Lyssand, Joseph Beechem	Bruker Spatial Biology, Seattle, WA	Decoding cancer hallmarks through single-cell whole transcriptome imaging in invasive ductal carcinoma 4/20/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 2 Open abstract	CosMx
4403	Eric Chabrol, Marie-Claire Phélipot, Cécile Lemoigne, Julie Lichière, Nadjiba Marès, Alice Aymard, Alexandre Bagnolini, Sophie Mesnard, Caroline Huber, Matthieu Tassa, Ester Morgado, Jacques Fieschi	Mimabs, Marseille, France	A fast and robust development process providing new highly internalized anti-hHER2 antibody-drug conjugates 4/21/2026 9:00:00 AM | Antibody Technologies and Platforms 2 Open abstract	Beacon
4705	Cheryl Davis, Liz Bailey, Mollie McArthur, Melissa Tran, Ben Hoerner, Victoria Caruso, Helen Ketteringham, Corrine Silvio, Shannan Paul, Delaney McCormick, Jocelyn Saurbaugh, Chris Holding, Aliccia Koznecki, Dawn Lusk, Shorena Nadaraia-Hoke, Kathleen Hutchinson	Reaction Biology Europe GmbH, Freiburg im Breisgau, Germany | Reaction Biology Corp, Boston, MA | Reaction Biology Corp, Malvern, PA | Reaction Biology Corp, Hummelstown, PA | Reaction Biology Corp, Lancaster, PA | Reaction Biology Corp, Hershey, PA	A clearer picture of cachexia: Leveraging body composition imaging in C26 tumored mice 4/21/2026 9:00:00 AM | Metabolic Alterations in Colorectal and Gastrointestinal Cancers Open abstract	-
4795	Michael Emilio Patrick, Wei Yang, Liang Zhang, Isabel Lee, Stefan-Laural Rogers, Shanshan He, Christina Bailey, John Lyssand, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA	Investigating HER2+ tumor cell motility and angiogenesis in FFPE breast cancer in space and at scale with CosMx and nCounter multiomics 4/21/2026 9:00:00 AM | Angiogenesis Open abstract	CosMx; nCounter
4971	Chia-Ying Lee, Arya Bahrami, Yi Cui, Megan Vandenberg, Michael McKenna, Shanshan He, Mirko Corselli, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA	Integrated spatial multiomic mapping of glioblastoma microenvironments via proteomic and transcriptomic profiling 4/21/2026 9:00:00 AM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 1 Open abstract	GeoMx
4984	Joseph Zenga, Musaddiq Awan, Fumou Sun, Stuart J. Wong, Abdullah Memon, Tyce Kearl, Ean Norenberg, Margaret L. Hoang, Joseph M. Beechem, Eric Hobbs, Ashley Heck, Rachel Liu, Daniel McGuire, Erin Piazza, Peiman Hematti, Heather Himburg	Medical College of Wisconsin, Milwaukee, WI | Bruker Spatial Biology, Seattle, WA | Bruker Spatial Biology, Piedmont, CA | Bruker Cellular Analysis, Emeryville, CA	Dissociative, spatial, and functional single-cell profiling reveals antigen-driven exhaustion and chemotactic failure of tumor-reactive T cells in HPV-negative HNSCC 4/21/2026 9:00:00 AM | Tumor-Immune Crosstalk Open abstract	CosMx; Beacon
5197	Maliha Munir, Madison Moore, Silvia Tiberti, Rafet Basar, Byron Jia, Leen Kheirbek, Nadima Uprety, Francia Reyes Silva, Rejeena Shrestha, Ana K. Nunez Cortes, Mayra Shanley, Sunil Acharya, Jeong-Min Park, Bin Liu, Pinaki Banerjee, Paul Lin, Donghai Xiong, Enli Liu, Alia Ghrayeb, Eyal Gottlieb, Elizabeth Joan Shpall, Katayoun Rezvani, May Daher	UT MD Anderson Cancer Center, Houston, TX | Molecular and Cellular Oncology, UT MD Anderson Cancer Center, Houston, TX | Professor of Medicine, Dept. of Stem Cell Transplant & Cell Therapy, UT MD Anderson Cancer Center, Houston, TX	Metabolically supercharged NK cells engineered with adenoviral E4ORF-1 4/21/2026 9:00:00 AM | Adoptive Cell Therapy 2 Open abstract	-
5733	Davin Pan, Shiori Fukutome, Diego De Luna Moran, Chunli Yan, Diego Alejandro Velarde, Whitaker Cohn, Ite A. Offringa	USC Norris Comprehensive Cancer Center, Los Angeles, CA | Department of Clinical Pharmacy, USC Mann School of Pharmacy, Los Angeles, CA	Decoding ELAVL4 isoaspartylation in SCLC using engineered PCMT1: A strategy for uncovering immune triggers 4/21/2026 2:00:00 PM | Molecular Targets 2 Open abstract	-
5923	Yi Cui, Marena I. Trinidad, Nurel Arriaran, Isabel Lee, Chia-Ying Lee, Shanshan He, Timothy Riordan, Joseph Beechem, Alexander E. Ehrenberg, Hanqin Li	Bruker Spatial Biology, Seattle, WA | Innovative Genomics Institute, Berkeley, CA	Optical pooled CRISPR screening coupling multiplexed guide RNA detection and single-cell spatial multi-omics 4/21/2026 2:00:00 PM | Genetic and Transcriptomic Dissection of Cancer Evolution Open abstract	CosMx
5953	Michael Patrick, Liang Zhang, Isabel Lee, Shanshan He, Martin Shelton, John Lyssand, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA	Unlocking new frontiers in mouse research by exploring the whole-transcriptome in space and time with mouse embryo stages E11 - E14 4/21/2026 2:00:00 PM | Mechanisms and Dynamics of Gene Expression Open abstract	CosMx
6199	Tengyu Zhang, Assya Legrini, Mari-Claire McGuigan, Stephan B. Dreyer, Ghazal Latifi, Claire Kennedy Dietrich, Hannah Morgan, Eva Verkolf, Virginia Padoan, Yoana Doncheva, Joao Da Silva Filho, Michail Doukas, Bas Groot Koerkamp, Joanne Edwards, Nigel Jamieson	School of Cancer Science, Univ. of Glasgow, Glasgow, United Kingdom | Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands | School of Infection and Immunity, Univ. of Glasgow, Glasgow, United Kingdom | Pathology and Clinical Bioinformatics, Erasmus Medical Centre, Rotterdam, Netherlands	Spatially revealed malignant and microenvironment ecosystems in PanIN- and IPMN-derived PDAC 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	CosMx
6201	Matija Snuderl, Yuxiu Wang, Neha Dhasmana, Pamela Flatley, Stacy Elliott, Douglas Werner, Jude Dunne, Huy Nguyen, Shyamtanu Chattoraj	NYU Langone Health, New York, NY | Bruker Spatial Genomics, San Jose, CA	PaintScapeTM enables multiomic in-situ direct visualization of spatial 3D genome architecture of single cells in intact fresh frozen Glioblastoma tissue in native tumor microenvironments 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	PaintScape
6208	Liang Zhang, Isabel Lee, Shanshan He, Martin Shelton, Owen J. Sansom, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA | Cancer Research UK Scotland Institute, Glasgow, United Kingdom	Subcellular imaging of murine models of metastatic colorectal cancer using a whole transcriptome spatial molecular imaging panel 4/21/2026 2:00:00 PM | Spatial Niches and Functional Boundaries within the Tumor Microenvironment 2 Open abstract	CosMx
6549	Yi Cui, Moumita Nath, Michael Emilio Patrick, Claire Williams, Daniel McGuire, Jobin K. Paul, Kowshik Jaganathan, Biswajit Das, Mohit Malhotra, Shanshan He, Joseph M. Beechem, Satish Sankaran	Bruker Spatial Biology, Seattle, WA | Farcast Biosciences India, Bengaluru, India	Integrating functional biosignatures and same-cell spatial multiomics to predict synergistic benefit of combination checkpoint therapy in head and neck cancer 4/21/2026 2:00:00 PM | Immune Checkpoint Blockade Open abstract	CosMx; nCounter
6591	Daniel Jimenez-Sanchez, Matthew H. Ingalls, Sanghamithra korukonda, Brian J. Lane, Isabella Marie Peshek, Patrick Danaher, Prajan Divakar, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO | Bruker Spatial Biology, Seattle, WA | Division of Gastroenterology, Northwestern University, Chicago, IL	Cross platform same slide multi-omics reveals Treg heterogeneity and links to spatial niche variability in pre-cancerous colonic inflammation 4/21/2026 2:00:00 PM | Inflammation, Immunity, and Cancer Open abstract	CosMx; CellScape
6659	Beatrice Wendler Awasthi, Nicole A. Lester, Deniz Guney Olgun, Yi Cui, Gabriel Francisco Pozo Mattos Pereira, Nicholas Caldwell, Mari Mino-Kenudson, Maria Ganci, Manisha Madhavan, Sierra Mckinzie, Jung Woo Bae, Xunqin Yin, Shanshan He, PRAJAN DIVAKAR, Martin Hemberg, Joe Beechem, William L. Hwang	Massachusetts General Hospital, Boston, MA | University of Virginia, Charlottesville, VA | Bruker Spatial Biology, Seattle, WA | Bruker Spatial Biology, Seattle, MA | Brigham and Women's Hospital, Boston, MA	Spatial proteo-transcriptomic profiling of pancreatic adenocarcinoma unveils distinct malignant subtype-associated immune and stromal functional states 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	-
6660	Daniel Jimenez-Sanchez, Brian J. Lane, Matthew H. Ingalls, Charles Eldon Jackson, Steven T. Lott, Adam Northcutt, Arne Christians, Anke Brix, Jennifer Brooks, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO | Bruker Spatial Biology, Hanover, Germany	CellScape Quality Control (CSQC): A tissue- and protein-agnostic platform for spatial proteomics quality assessment 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	CellScape
6664	Terence C. Theisen, Alexa E. Lasley, Giang Ong, Megan Vandenberg, Brian Filanoski, Lori Hamanishi, Erin Piazza, Sayani Bhattacharjee, Courtney Anderson, Mirko Corselli, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Single-cell spatial proteomics of 1200+ protein targets in tumor microenvironments from diverse cancers using GeoMx Discovery Proteome Atlas 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	GeoMx
6672	Thore Boettke, Jannik Boog, Charles Eldon Jackson, Matthew H. Ingalls, Arne Christians, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO	Expanding the boundaries of spatial proteomics with a universal antibody labeling strategy and EpicIF™ multiplexing chemistry 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	CellScape
6678	Arne Christians, Thore Boettke, Jannik Boog, Charles Eldon Jackson, Matt Ingalls, Brian J. Lane, Daniel Jimenez Sanchez, Christoph Rocken, Niclas Christian Blessin, Oliver Braubach	Bruker Spatial Biology, St. Louis, MO | Dept. of Pathology, University Medical Center Schleswig-Holstein, Kiel, Germany	Ultra-high-plex immunofluorescence analysis of the tumor-immune microenvironment with EpicIF technology on the CellScape platform 4/21/2026 2:00:00 PM | Spatial Proteomics and Transcriptomics 3 Open abstract	CellScape
6755	M. Dhainaut, L. Zhang, M. Meister, A. Mavropoulos, A. Benz, I. Lee, S. McKinzie, D. Millman, D. Tran, D. Ovando, L. Cavalcante, K. Mitchell, E. Margalit, D. Antonio, A. Mahajan, A. Salm, E. Siefkas, F. Fernandez, H. Kaplan, H. Winters, J. Schmidt, J. Tea, J. Decalf, L. Ryan, M. Zolanvari, N. Snell, R. Schiemann, R. Collins, R. Huang, Y. Xie, Y. Falanga, S. Virani, L. Padron, E. Corse, S. He, D. Bear, J. M. Beechem, R. W. Alfa; Noetik, San Francisco, CA, Bruker Spatial Biology, Seattle, WA		Unbiased phenotyping of CRISPR-edited tumors with Perturb-map and subcellular imaging of the mouse whole transcriptome (22,000-plex) 4/21/2026 4:05:00 PM | Spatial Biomarkers at Single-Cell Resolution: Mapping Tumor Ecosystems with Proteomics, Transcriptomics, and AI Open abstract	CosMx
7235	Yi Cui, Huy Nguyen, Andrea Floris, David King, Serdar Tulu, David Castillo, Shanshan He, Shyamtanu Chattoraj, Jude Dunne, Mirko Corselli, John Lyssand, Joseph M. Beechem	Bruker Spatial Biology, Seattle, WA | Bruker Spatial Genomics, San Jose, CA	Integrated spatial multiomic profiling of 3D genome architecture and transcriptome-wide gene expression in breast cancer models 4/22/2026 9:00:00 AM | Chromatin Architecture and Regulatory Landscapes Open abstract	CosMx; PaintScape
7243	Huy Nguyen, Sophie Pribus, Zhicheng Ma, David King, Johnson Huynh, Serdar Tulu, Marc Glazer, Brian Smart, David Castillo, Kenny Chung, Shyamtanu Chattoraj, Jude Dunne, Doug Werner, Christina Curtis, Mark Munch	Bruker Spatial Genomics, San Jose, CA | Stanford University, Stanford, CA	In-situ direct single-cell visualization of 3D genome architecture in ER+ and HER2+ breast cancer cell lines using PaintScapeTM system 4/22/2026 9:00:00 AM | Chromatin Architecture and Regulatory Landscapes Open abstract	PaintScape
7311	LUIS DEL POZO-YAUNER, Veronica Ramirez-Alcantara, Elba A. Turbat-Herrera, Hector Chavarria Bernal, Maha Babker, Huseyin Kilic, Rosetta Campbell, Bahaaeldin Youssef, Ajay Singh, Julio Isael Perez-Carreon, Wei Yang, Guillermo A. Herrera	Pathology, University of South Alabama College of Medicine, Mobile, AL | USA Health Mitchell Cancer Institute, Mobile, AL | University of South Alabama College of Medicine, Mobile, AL | SOM-Cell and Molecular Biology, University of Mississippi Medical Center and Cancer Center and Research Institute, Jackson, MS | National Institute of Genomic Medicine, Mexico City, Mexico | Bruker Spatial Biology, Seattle, WA	Characterization of PERK-positive polyploid-like breast cancer cells and their association with unfolded protein response signatures 4/22/2026 9:00:00 AM | Hypoxic and Proteotoxic Stress Response Open abstract	nCounter
7421	Meagan Marie Ybarra, Xiaoyu Yang, Siri Borra, Chia-Nung Hung, John Baer, Ramya Chengalvala, Rolando Trevino Jr, Shaye Hagler, Sung-Jen Wei, Joel Michalek, Zhao Zhang, Sukeshi A. Patel, Danielle Fritze, Glenn Halff, Zhao Lai, Yuji Ikeno, Yidong Chen, Rita Ghosh, Addanki Pratap Kumar	Molecular Medicine, UT Health Science Center at San Antonio, San Antonio, TX | UT Health Science Center at San Antonio, San Antonio, TX | Bruker Spatial Biology, St. Louis, MO | Radiation Oncology, UT Health Science Center at San Antonio, San Antonio, TX | Population Health Sciences, Mays Cancer Center, UT Health Science Center at San Antonio, San Antonio, TX | Mays Cancer Center, Medicine, UT Health Science Center at San Antonio, San Antonio, TX | Surgery, UT Health Science Center at San Antonio, San Antonio, TX | Greehey Children's Cancer, San Antonio, TX | Pathology & Laboratory Medicine, UT Health Science Center at San Antonio, San Antonio, TX | Population Health Sciences, Mays Cancer Center, Greehey Childrens Cancer Institute, UT Health Science Center at San Antonio, San Antonio, TX | Molecular Medicine, Urology, Pharmacology, UT Health Science Center at San Antonio, San Antonio, TX	Palmatine modulates tumor microenvironment and improves gemcitabine efficacy in PDAC via HOXA10-STAT3 axis suppression 4/22/2026 9:00:00 AM | Microenvironmental Determinants of Therapy Response and Resistance 2 Open abstract	-
7661	Brian Filanoski, Lori Hamanishi, Giang Ong, Terence C. Theisen, Erin Piazza, Christina Bailey, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Integrated multiomics profiling of lysates using nCounter® protein and RNA panels for comprehensive oncology insights 4/22/2026 9:00:00 AM | Multi-Omics, Systems Biology, and Biological Mass Spectrometry Open abstract	nCounter
7663	Cameron Ellis, Arhur Viodé, Anamarija Pfeiffer, Lucy Yang, Monika Pepelnjak, George Rosenberger, Polina Shichkova, Kristina Marx, Christopher Below, Roland Bruderer	PreOmics Inc., Billerica, MA | Biognosys AG, Schlieren, Switzerland | Bruker Daltonics GmbH & Co. KG, Bremen, Germany	Discovery of tumor-specific and neoantigenic peptides in cancer tissue samples using mass spectrometry-based immunopeptidomic 4/22/2026 9:00:00 AM | Multi-Omics, Systems Biology, and Biological Mass Spectrometry Open abstract	-
7665	Giang Ong, Terence C. Theisen, Brian Filanoski, Lori Hamanishi, Erin Piazza, Christina Bailey, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem	Research and Development, Bruker Spatial Biology, Seattle, WA	Multi-step antibody validation for nCounter high-plex multiomics panels 4/22/2026 9:00:00 AM | Multi-Omics, Systems Biology, and Biological Mass Spectrometry Open abstract	nCounter
7698	Cameron Ellis, Katharina Limm, Sandra Schär, Roland Bruderer, Nils Kulak	PreOmics Inc., Billerica, MA | PreOmics GmbH, Planegg/Martinsried, Germany | Biognosys AG, Zurich, Switzerland	Advancing plasma proteomics: A next-generation nanoparticle enrichment workflow for deep and quantitative biomarker discovery in colorectal cancer 4/22/2026 9:00:00 AM | Proteomics: Biomarker Discovery and Signaling Networks Open abstract	-
7700	Antolize Deetlefs, Charne Scully, Hafiza Parkar, Andrea Ellero, Amy van Graan, Melissa Vorster, Justin Jordaan, Previn Naicker	Department of Pharmacology, University of Pretoria, Pretoria, South Africa | ReSyn Biosciences, Pretoria, South Africa	Secretomic profiling of triple-negative breast cancer media using Mag-Net™ HP 4/22/2026 9:00:00 AM | Proteomics: Biomarker Discovery and Signaling Networks Open abstract	-
	Thomas Campbell. Bruker Spatial Biology, St. Louis, MO		Resolving cancer across its biological layers with single-cell and spatial biology 4/20/2026 10:00:00 AM | Resolving Cancer Across Its Biological Layers with Single-Cell and Spatial Biology Open abstract	-
	Jude Dunne. Bruker Spatial Genomics, Menlo Park, CA		Resolving cancer across its biological layers with single-cell and spatial biology 4/20/2026 10:00:00 AM | Resolving Cancer Across Its Biological Layers with Single-Cell and Spatial Biology Open abstract	-
	Joseph M. Beechem. Bruker Spatial Biology, Piedmont, CA		Resolving cancer across its biological layers with single-cell and spatial biology 4/20/2026 10:00:00 AM | Resolving Cancer Across Its Biological Layers with Single-Cell and Spatial Biology Open abstract	-